“The international classification of retinopathy of prematurity (ROP)(The 3rd edition)”, retains current definitions such as zone, stage, and circumferential extent of disease, however, there are also many updates. Major updates include: (1) increase of the definition of posterior pole Ⅱ; (2) introduction of a new concept "notch"; (3) definition of stage 5's subcategorization; (4) recognition that a continuous spectrum of vascular abnormality exists from normal to plus disease. Updates also include the definition of “aggressive ROP” to replace “aggressive-posterior ROP”. ROP regression and reactivation are described in detail, with additional description of long-term sequelae.
Citation： Fei Ping, Zhao Peiquan. Brief interpretation of the international classification of retinopathy of prematurity (third edition). Chinese Journal of Ocular Fundus Diseases, 2021, 37(12): 915-919. doi: 10.3760/cma.j.cn511434-20210726-00395 Copy
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