Observation of the Clinical Effect of Suxiao Jiuxin Pills on Patients with Acute Coronary Syndrome_West China Medical Journal

Authors：

 ZHANGLei ¹ , LIHao ²

1. Department of Pharmacy, the First People's Hospital of Yibin, Yibin, Sichuan 644000, P. R. China;
2. Department of Neurology, the First People's Hospital of Yibin, Yibin, Sichuan 644000, P. R. China;

Corresponding author：

Keywords：

Acute coronary syndrome; Clopidogrel; Suxiao Jiuxin Pill

DOI：

10.7507/1002-0179.20140003

Video：

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Objective To observe the clinical effect of clopidogrel combined with Suxiao Jiuxin Pills on patients with acute coronary syndrome (ACS). Methods Ninety-seven patients with ACS diagnosed between January 2010 and December 2011 were divided into the treatment group (treated with clopidogrel combined with Suxiao Jiuxin Pills) (n=48) and the control group (treated with single clopidogrel) (n=49). One month was regarded as a treatment course. After one month, we observed the clinical effect, heart attacks frequency, ST segment changes and adverse reactions for the patients. Results The total effective rate was 79.2% in the treatment group and was 51.0% in the control group. There was significant difference between the two groups (P<0.05). Heart attacks frequency and ST segment were reduced significantly in both the two groups after treatment (P<0.05). The curative effect in the treatment group was significantly better than that in the control group after treatment (P<0.05). Conclusion Clopidogrel combined with Suxiao Jiuxin Pills have a better clinical effect in the treatment of ACS than single clopidogrel.

Citation： ZHANGLei, LIHao. Observation of the Clinical Effect of Suxiao Jiuxin Pills on Patients with Acute Coronary Syndrome. West China Medical Journal, 2014, 29(1): 8-10. doi: 10.7507/1002-0179.20140003 Copy

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9.	孙世仁, 黄熙, 张莉. 速效救心丸的药动-药效学及临床研究进展[J]. 中草药, 2002, 33(1):89-91.
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11.	翟丽秋. 速效救心丸与硝酸甘油片急救心绞痛110例疗效观察[J]. 中国医药导报, 2008, 5(9):165.
12.	曹生海, 燕小霞, 张嘉毅, 等. 速效救心丸短期治疗冠心病心绞痛105例疗效观察[J]. 中成药, 2007, 29(4):486-488.
13.	高云颂, 钱秋玉, 郝影霞. 速效救心丸与消心痛治疗老年冠心病心绞痛对照研[J]. 北京中医, 2006, 25(5):320-321.

1. 叶姗, 何国平, 惠静姣, 等. 血清白三烯B4水平与急性冠脉综合征发病风险和易患因素的相关性分析[J]. 江苏大学学报(医学版), 2012, 22(1):73-76.
2. Braunwald E, Antman EM, Beasley JW, et al. ACC/AHA guidelines for the management of patients with unstableangina and non-ST-segment elevation myocardial infarction:a report of the American College of ardiology/American Heart Association[J]. J Am Coll Cardiol, 2000, 36(3):970-1062.
3. 郑筱萸主编. 中药新药临床研究指导原则(试行)[M]. 北京:中国医药科技出版社, 2002:72-73.
4. 陈营清, 李宇琛. 氯吡格雷治疗不稳定型心绞痛疗效观察[J]. 华西医学, 2009, 24(2):3185-3186.
5. 施海. 速效救心丸治疗冠心病心绞痛40例[J]. 中成药, 2002, 24(1):852-854.
6. 关晶, 曲竹秋, 王莎莎. 速效救心丸对动脉粥样硬化大鼠干预作用的实验研究[J].天津中医药, 2009, 26(6):486-488.
7. 冯玲, 王阶, 陈双厚, 等. 速效救心丸对大鼠心肌梗死模型血管新生作用的影响[J]. 中国中药杂志, 2009, 34(6):748-750.
8. 尚俊枝, 刘晓红. 注射用红花黄色素联合速效救心丸治疗不稳定型心绞痛疗效观察[J]. 实用医技杂志, 2012, 19(3):241-242.
9. 孙世仁, 黄熙, 张莉. 速效救心丸的药动-药效学及临床研究进展[J]. 中草药, 2002, 33(1):89-91.
10. 段可杰, 张聪宇, 杨晓燕. 速效救心丸治疗冠心病心绞痛40例临床观察[J]. 天津中医, 2002, 19(1):20-21.
11. 翟丽秋. 速效救心丸与硝酸甘油片急救心绞痛110例疗效观察[J]. 中国医药导报, 2008, 5(9):165.
12. 曹生海, 燕小霞, 张嘉毅, 等. 速效救心丸短期治疗冠心病心绞痛105例疗效观察[J]. 中成药, 2007, 29(4):486-488.
13. 高云颂, 钱秋玉, 郝影霞. 速效救心丸与消心痛治疗老年冠心病心绞痛对照研[J]. 北京中医, 2006, 25(5):320-321.

West China Medical Journal

Observation of the Clinical Effect of Suxiao Jiuxin Pills on Patients with Acute Coronary Syndrome

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