Exploration of evidence-based medicine curriculum reform in the information age_Chinese Journal of Evidence-Based Medicine

Authors：

XU Jiayue ^1,2,3 , WANG Yuning ^1,2,3 , SUN Xin ^1,2,3,4 ,  WANG Wen ^1,2,3

1. Chinese Evidence-based Medicine Center, West China Hospital, Sichuan University, Chengdu 610041, P. R. China;
2. NMPA Key Laboratory for Real World Data Research and Evaluation in Hainan, Chengdu 610041, P. R. China;
3. Sichuan Center of Technology Innovation for Real World Data, Chengdu 610041, P. R. China;
4. West China School of Public Health, Sichuan University, Chengdu 610041, P. R. China;

Corresponding author：

WANG Wen, Email: wangwen83@outlook.com

Keywords：

Evidence-based medicine; Course reform; Interdisciplinarity; Real-world data; Artificial intelligence; Bioinformatics

DOI：

10.7507/1672-2531.202401168

Video：

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Evidence-based medicine is the methodology of modern clinical research and plays an important role in guiding clinical practice. It has become an integral part of medical education. In the digital age, evidence-based medicine has evolved to incorporate innovative research models that utilize multimodal clinical big data and artificial intelligence methods. These advancements aim to address the challenges posed by diverse research questions, data methods, and evidence sources. However, the current teaching content in medical schools often fails to keep pace with the rapidly evolving disciplines, impeding students' comprehensive understanding of the discipline's knowledge system, cutting-edge theories, and development directions. In this regard, this article takes the opportunity of graduate curriculum reform to incorporate real-world data research, artificial intelligence, and bioinformatics into the existing evidence-based medicine curriculum, and explores the reform of evidence-based medicine teaching in the information age. The aim is to enable students to truly understand the role and value of evidence-based medicine in the development of medicine, while possessing a solid theoretical foundation, a broad international perspective, and a keen research sense, in order to cultivate talents for the development of the evidence-based medicine discipline.

Citation： XU Jiayue, WANG Yuning, SUN Xin, WANG Wen. Exploration of evidence-based medicine curriculum reform in the information age. Chinese Journal of Evidence-Based Medicine, 2024, 24(5): 612-616. doi: 10.7507/1672-2531.202401168 Copy

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2.	Evidence-Based Medicine Working Group. Evidence-based medicine. A new approach to teaching the practice of medicine. JAMA, 1992, 268(17): 2420-2425.
3.	Marshall J, Ross S, Buchanan P, et al. Providing effective evidence based support for breastfeeding women in primary care. BMJ, 2021, 375: e065927.
4.	Peng L, Zhang K, Li Y, et al. Real-world evidence of traditional Chinese medicine (TCM) treatment on cancer: a literature-based review. Evid Based Complement Alternat Med, 2022, 2022: 7770380.
5.	Zeng L, Walsh M, Guyatt GH, et al. Plasma exchange and glucocorticoid dosing for patients with ANCA-associated vasculitis: a clinical practice guideline. BMJ, 2022, 376: e064597.
6.	Carson JL, Stanworth SJ, Guyatt G, et al. Red blood cell transfusion: 2023 AABB international guidelines. JAMA, 2023, 330(19): 1892-1902.
7.	Harris E. CDC introduces hospital sepsis program guidelines. JAMA, 2023, 330(12): 1128.
8.	Gilbert R, Salanti G, Harden M, et al. Infant sleeping position and the sudden infant death syndrome: systematic review of observational studies and historical review of recommendations from 1940 to 2002. Int J Epidemiol, 2005, 34(4): 874-887.
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12.	Dorsch JL, Aiyer MK, Meyer LE. Impact of an evidence-based medicine curriculum on medical students' attitudes and skills. J Med Libr Assoc, 2004, 92(4): 397-406.
13.	Psaty BM, Siscovick DS. Minimizing bias due to confounding by indication in comparative effectiveness research: the importance of restriction. JAMA, 2010, 304(8): 897-898.
14.	Lund JL, Richardson DB, Stürmer T. The active comparator, new user study design in pharmacoepidemiology: historical foundations and contemporary application. Curr Epidemiol Rep, 2015, 2(4): 221-228.
15.	Yoshida K, Solomon DH, Kim SC. Active-comparator design and new-user design in observational studies. Nat Rev Rheumatol, 2015, 11(7): 437-441.
16.	复旦大学. 中国大学MOOC(慕课): 循证医学. 2023.
17.	张维璐, 邵中军, 苏海霞, 等. 医学院校硕士研究生科研素养提升教学模式探讨—以《临床流行病学与循证医学》课程为例. 医学教育研究与实践, 2023, 31(5): 552-556.
18.	刘智洁, 郑紫薇, 肖元梅, 等. 医学研究生循证能力的表现形式及培养方式. 医学教育管理, 2023, 9(5): 599-604.
19.	Thomas A, Chin-Yee B, Mercuri M. Thirty years of teaching evidence-based medicine: have we been getting it all wrong. Adv Health Sci Educ Theory Pract, 2022, 27(1): 263-276.
20.	Subbiah V. The next generation of evidence-based medicine. Nat Med, 2023, 29(1): 49-58.
21.	Luo J, Wu M, Gopukumar D, et al. Big data application in biomedical research and health care: a literature review. Biomed Inform Insights, 2016, 8: 1-10.
22.	Djulbegovic B, Guyatt GH. Progress in evidence-based medicine: a quarter century on. Lancet, 2017, 390(10092): 415-423.
23.	Siemieniuk RA, Agoritsas T, Macdonald H, et al. Introduction to BMJ rapid recommendations. BMJ, 2016, 354: i5191.

1. Sackett DL, Rosenberg WM, Gray JA, et al. Evidence based medicine: what it is and what it isn't. BMJ, 1996, 312(7023): 71-72.
2. Evidence-Based Medicine Working Group. Evidence-based medicine. A new approach to teaching the practice of medicine. JAMA, 1992, 268(17): 2420-2425.
3. Marshall J, Ross S, Buchanan P, et al. Providing effective evidence based support for breastfeeding women in primary care. BMJ, 2021, 375: e065927.
4. Peng L, Zhang K, Li Y, et al. Real-world evidence of traditional Chinese medicine (TCM) treatment on cancer: a literature-based review. Evid Based Complement Alternat Med, 2022, 2022: 7770380.
5. Zeng L, Walsh M, Guyatt GH, et al. Plasma exchange and glucocorticoid dosing for patients with ANCA-associated vasculitis: a clinical practice guideline. BMJ, 2022, 376: e064597.
6. Carson JL, Stanworth SJ, Guyatt G, et al. Red blood cell transfusion: 2023 AABB international guidelines. JAMA, 2023, 330(19): 1892-1902.
7. Harris E. CDC introduces hospital sepsis program guidelines. JAMA, 2023, 330(12): 1128.
8. Gilbert R, Salanti G, Harden M, et al. Infant sleeping position and the sudden infant death syndrome: systematic review of observational studies and historical review of recommendations from 1940 to 2002. Int J Epidemiol, 2005, 34(4): 874-887.
9. Tan J, Liu C, Li M, et al. A methodological framework for tackling confounding by indication when assessing the treatment effects of Chinese herbal injections in the real world. J Evid Based Med, 2022, 15(1): 64-72.
10. 樊鹏. 第四次工业革命带给世界的深刻变革. 人民论坛, 2021, (Z1): 41-45.
11. Al Shahrani AS. Development and evaluation of an evidence-based medicine module in the undergraduate medical curriculum. BMC Med Educ, 2020, 20(1): 256.
12. Dorsch JL, Aiyer MK, Meyer LE. Impact of an evidence-based medicine curriculum on medical students' attitudes and skills. J Med Libr Assoc, 2004, 92(4): 397-406.
13. Psaty BM, Siscovick DS. Minimizing bias due to confounding by indication in comparative effectiveness research: the importance of restriction. JAMA, 2010, 304(8): 897-898.
14. Lund JL, Richardson DB, Stürmer T. The active comparator, new user study design in pharmacoepidemiology: historical foundations and contemporary application. Curr Epidemiol Rep, 2015, 2(4): 221-228.
15. Yoshida K, Solomon DH, Kim SC. Active-comparator design and new-user design in observational studies. Nat Rev Rheumatol, 2015, 11(7): 437-441.
16. 复旦大学. 中国大学MOOC(慕课): 循证医学. 2023.
17. 张维璐, 邵中军, 苏海霞, 等. 医学院校硕士研究生科研素养提升教学模式探讨—以《临床流行病学与循证医学》课程为例. 医学教育研究与实践, 2023, 31(5): 552-556.
18. 刘智洁, 郑紫薇, 肖元梅, 等. 医学研究生循证能力的表现形式及培养方式. 医学教育管理, 2023, 9(5): 599-604.
19. Thomas A, Chin-Yee B, Mercuri M. Thirty years of teaching evidence-based medicine: have we been getting it all wrong. Adv Health Sci Educ Theory Pract, 2022, 27(1): 263-276.
20. Subbiah V. The next generation of evidence-based medicine. Nat Med, 2023, 29(1): 49-58.
21. Luo J, Wu M, Gopukumar D, et al. Big data application in biomedical research and health care: a literature review. Biomed Inform Insights, 2016, 8: 1-10.
22. Djulbegovic B, Guyatt GH. Progress in evidence-based medicine: a quarter century on. Lancet, 2017, 390(10092): 415-423.
23. Siemieniuk RA, Agoritsas T, Macdonald H, et al. Introduction to BMJ rapid recommendations. BMJ, 2016, 354: i5191.

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