Further Discussion on Living Donor Liver Transplantation_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

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王学浩 , 李国强

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Keywords：

肝移植; 活体; 供体; 免疫抑制剂; 急诊

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自1989年巴西医生Raia开展人类首例活体肝移植（living donor liver transplantation, LDLT）以来，LDLT受体的优良预后及供体的安全性逐步得到了公认，加之“脑死亡”供肝的严重匮乏，LDLT技术迅速发展并被公认为是缓解供肝来源匮乏最有效的方法之一［1，2］。LDLT技术的发展大致经历了三个阶段： ①成人→儿童间活体肝移植（简称儿童活体肝移植，pediatric living donor liver transplantation, PLDLT）； ②成人→成人间活体肝移植(adulttoadult living donor liver transplantation, ALDLT)； ③急诊活体肝移植(emergency or highurgency living donor liver transplantation, ELDLT )。LDLT技术发展的每一阶段均是对前一阶段技术的总结和升华，技术难度和复杂性也逐步增加。

Citation： 王学浩,李国强. Further Discussion on Living Donor Liver Transplantation. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2003, 10(4): 318-320. doi: Copy

1.	Emre S. Living donor liver transplantation: a critical review [J]. Transplant Proc, 2001; 33(7-8)∶3456.
2.	Inomata Y, Uemoto S, Asonuma K, et al. Right lobe graft in living donor liver transplantation [J]. Transplantation, 2000; 69(2)∶258.
3.	王学浩, 杜竞辉, 张峰, 等. 首例活体供肝原位部分肝移植报告 [J]. 中国实用外科杂志, 1995; 15(5)∶273.
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5.	Beavers KL, Sandler RS, Fair JH,et al. The living donor experience: donor health assessment and outcomes after living donor liver transplantation [J]. Liver Transpl, 2001; 7(11)∶943.
6.	王学浩,张峰,李相成,等.五例活体肝移植供体术后随访报告 [J].江苏医药, 2001; 27(10)∶729.
7.	王学浩,张峰,李相成,等.活体部分肝移植12例次临床报告 [J].中华医学杂志, 2002; 82(7)∶19.
8.	Marcos A. Right lobe living donor liver transplantation: a review [J]. Liver transpl， 2000; 6(1)∶3.
9.	李国强,王学浩.活体肝移植临床研究的新进展 [J].中国普外基础与临床杂志, 2002; 9(4)∶279.
10.	Fan ST, Lo CM, Liu CL, et al. Safety of donors in live donor liver transplantation using right lobe grafts [J].Arch Surg, 2000; 135(3)∶336.
11.	Marcos A, Fisher RA, Ham JM, et al. Right lobe living donor living transplantation [J].Transplantation, 1999; 68(6)∶798.
12.	Nakamura S, Suzuki S, Yokoi Y. Indications for and techniques of hepatic vein reconstruction in hepatectomy for hepatocellular carcinoma [J]. Nippon Geka Gakkai Zasshi, 2001; 102(11)∶805.
13.	Sugawara Y, Makuuchi M, Takayama T,et al. Right lateral sector graft in adult livingrelated liver transplantation [J]. Transplantation, 2002; 73(1)∶111.
14.	Sugawara Y, Makuuchi M, Takayama T,et al. Liver transplantation using a right lateral sector graft from a living donor to her granddaughter [J]. Hepatogastroenterology, 2001; 48 (37)∶261.
15.	王学浩, 李国强, 李相成, 等. 活体肝移植手术经验回顾 [J]. 中国实用外科杂志, 2002; 22(6)∶89.
16.	Kelly D, Jara P, Rodeck B, et al. Tacrolimus dual therapy versus cyclosporinmicroemulsion triple therapy in paediatric liver transplantation: results from a multicentre randomized trial [J]. Am J Transpl， 2002; 2(Suppl 3)∶351.
17.	Kumar A, Jain B, Polharna R, et al. Tacrolimus offers almost total absence of chronic rejection in pediatric liver transplant recipient: follow up of 7-10 years [J]. Am J Transpl, 2002; 2(Suppl 3)∶352.
18.	Uemoto S, Inomata Y, Sakuri T, et al. Living donor liver transplantation for fulminant hepatic failure [J].Transplantation, 2000; 70(1)∶152.
19.	Bismuth H, Samuel D, Castaing D, et al. Orthotopic liver transplantation in fulminant and subfulminant hepatitis. The Paul Brouses experience [J]. Ann Surg, 1995; 222(2)∶109.
20.	Washburn WK, Bradley J, Cosimi AB, et al. A regional experience with emergency liver transplantation [J].Transplantation,2000; 61(2)∶235.
21.	Lo CM, Fan ST, Liu CL, et al. Applicability of living donor liver transplantation to highurgency patients [J]. Transplantation,1999; 67(1)∶73.
22.	Marcos A, Ham JM, Fisher RA, et al. Emergency adult to adult living donor liver transplantation for fulminant hepatic failure [J].Transplantation, 2000; 69(10)∶2202.

1. Emre S. Living donor liver transplantation: a critical review [J]. Transplant Proc, 2001; 33(7-8)∶3456.
2. Inomata Y, Uemoto S, Asonuma K, et al. Right lobe graft in living donor liver transplantation [J]. Transplantation, 2000; 69(2)∶258.
3. 王学浩, 杜竞辉, 张峰, 等. 首例活体供肝原位部分肝移植报告 [J]. 中国实用外科杂志, 1995; 15(5)∶273.
4. Schulz KH, Hofmann C, Sander K,et al. Living organ donation vs. cadaveric donationstudy of liver transplanted children and their families [J]. Psychother Psychosom Med Psychol, 2001; 51(12)∶452.
5. Beavers KL, Sandler RS, Fair JH,et al. The living donor experience: donor health assessment and outcomes after living donor liver transplantation [J]. Liver Transpl, 2001; 7(11)∶943.
6. 王学浩,张峰,李相成,等.五例活体肝移植供体术后随访报告 [J].江苏医药, 2001; 27(10)∶729.
7. 王学浩,张峰,李相成,等.活体部分肝移植12例次临床报告 [J].中华医学杂志, 2002; 82(7)∶19.
8. Marcos A. Right lobe living donor liver transplantation: a review [J]. Liver transpl， 2000; 6(1)∶3.
9. 李国强,王学浩.活体肝移植临床研究的新进展 [J].中国普外基础与临床杂志, 2002; 9(4)∶279.
10. Fan ST, Lo CM, Liu CL, et al. Safety of donors in live donor liver transplantation using right lobe grafts [J].Arch Surg, 2000; 135(3)∶336.
11. Marcos A, Fisher RA, Ham JM, et al. Right lobe living donor living transplantation [J].Transplantation, 1999; 68(6)∶798.
12. Nakamura S, Suzuki S, Yokoi Y. Indications for and techniques of hepatic vein reconstruction in hepatectomy for hepatocellular carcinoma [J]. Nippon Geka Gakkai Zasshi, 2001; 102(11)∶805.
13. Sugawara Y, Makuuchi M, Takayama T,et al. Right lateral sector graft in adult livingrelated liver transplantation [J]. Transplantation, 2002; 73(1)∶111.
14. Sugawara Y, Makuuchi M, Takayama T,et al. Liver transplantation using a right lateral sector graft from a living donor to her granddaughter [J]. Hepatogastroenterology, 2001; 48 (37)∶261.
15. 王学浩, 李国强, 李相成, 等. 活体肝移植手术经验回顾 [J]. 中国实用外科杂志, 2002; 22(6)∶89.
16. Kelly D, Jara P, Rodeck B, et al. Tacrolimus dual therapy versus cyclosporinmicroemulsion triple therapy in paediatric liver transplantation: results from a multicentre randomized trial [J]. Am J Transpl， 2002; 2(Suppl 3)∶351.
17. Kumar A, Jain B, Polharna R, et al. Tacrolimus offers almost total absence of chronic rejection in pediatric liver transplant recipient: follow up of 7-10 years [J]. Am J Transpl, 2002; 2(Suppl 3)∶352.
18. Uemoto S, Inomata Y, Sakuri T, et al. Living donor liver transplantation for fulminant hepatic failure [J].Transplantation, 2000; 70(1)∶152.
19. Bismuth H, Samuel D, Castaing D, et al. Orthotopic liver transplantation in fulminant and subfulminant hepatitis. The Paul Brouses experience [J]. Ann Surg, 1995; 222(2)∶109.
20. Washburn WK, Bradley J, Cosimi AB, et al. A regional experience with emergency liver transplantation [J].Transplantation,2000; 61(2)∶235.
21. Lo CM, Fan ST, Liu CL, et al. Applicability of living donor liver transplantation to highurgency patients [J]. Transplantation,1999; 67(1)∶73.
22. Marcos A, Ham JM, Fisher RA, et al. Emergency adult to adult living donor liver transplantation for fulminant hepatic failure [J].Transplantation, 2000; 69(10)∶2202.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Further Discussion on Living Donor Liver Transplantation

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