Objective To evaluate the value of AccuMap multifocal visual evoked potential (mfVEP) objective perimetry in measuring visual function of macular diseases. Methods Forty-six eyes (37 patients) with macular diseases were studied. The mean mfVEP amplitudes of central visual field within radius 2.0 deg;, 5.5 deg;, 10.0 deg;, 15.5 deg; and 24.0 deg;were measured by AccuMap mfVEP objective perimetry. Automatically calculated AccuMap severity index （ASI） represented the visual field defects. Meanwhile, the mean sensitivity (MS) of central visual field within radius 2.0 deg;, 4.0 deg;, 6.0 deg;, 8.0 deg; and 10.0 deg; and mean defect (MD) of central visual field within radius 10.0 deg; were assessed by MP-1 microperimeter. The correlations among those parameters including logMAR visual acuity, mean mfVEP amplitudes, MS, ASI and MD were analyzed. Results Among 46 affected eyes, AccuMap mfVEP objective perimetry showed abnormal ASI with visual field defects in 43 eyes (93.45%), normal ASI without visual field defects in three eyes (6.55%). The mean mfVEP amplitudes value of the central visual field within radius of 2.0 deg;, 5.5 deg;, 10.0 deg;, 15.5 deg; and 24.0 deg; were (120.78 plusmn;52.91), (134.31 plusmn;54.67), (149.99 plusmn;52.42), (156.69 plusmn;48.30), (157.54 plusmn;45.07) nV respectively. The mean ASI value was 74.26 plusmn;52.43. MP1 showed that the MS values of central visual field within radius 2.0 deg;, 4.0 deg;, 6.0 deg;, 8.0 deg; and 10.0 deg; were (10.97 plusmn;5.91), (12.71 plusmn;5.13), (13.71 plusmn;4.53), (14.23 plusmn;4.18), (14.48 plusmn;3.86) dB respectively. The MD value of central visual field within radius 10 deg; was 4.49 plusmn;3.07. There was a significant correlation among ASI, the mean mfVEP amplitudes of central visual field with every radius and logMAR best corrected visual acuity （P＜0.05). The mean mfVEP amplitudes of central visual field within radius 2.0 deg;, 5.5 deg;, 10.0 deg; were positively correlated with the MS of central visual field within radius 2.0 deg;, 6.0 deg;, 10.0 deg; (r=0.477, 0.432, 0.433;P=0.001, 0.003, 0.003). Furthermore, ASI was also correlated with MD of central visual field within radius 10.0 deg;(r=0.729, P=0.000). Conclusions AccuMap mfVEP objective perimetry can reflect the changes of macular function objectively and can be used to assess the visual function of macular diseases.
Citation： 姜利斌,谢君,焦旋,周海英. Application of AccuMap multifocal visual evoked potential on visual function in macular diseases. Chinese Journal of Ocular Fundus Diseases, 2011, 27(2): 136-139. doi: Copy