• Department of Ophthalmology,EENT Hospital of Fuda n University, Shanghai 200031,China.;
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Objective To investigate the degree of retinal developmen t in pret erm infants and compare the electroretinograms between preterm and fullterm in fants. Methods Flash electroretinogram (ERG) were obtained wit h contact lens el ectrodes in one eye from ten preterm infants (10 eyes) and twenty full-term inf a nts (20 eyes) in seven days after birth. The rod cell, cone cell, maximal combi nation, oscillatory potentials, and 30 Hz flicker responses were recorded. Results Compared with the full-term infants, the implicit time of rod cell respon s e (t=3.216,P=0.003) was longer and the amplitudes were lower (t=6.0 50,P=0.000) in the preterm infants; the difference of implicit time of maximal response was not significant (t=0.465,P=0.650; t=1.068,P=0.295), while th e amplitudes dec reased (t=6.584, P=0.000; t=6.649, P=0.000). The a- and b-wav e implicit time of cone response was not differed much between the two groups (t=0.077, P=0.939; t=0.935,P=0.358); the amplitudes was obvious lower in preterm group (t =3 .417,P=0.002;t=6.310,P=0.000); the difference of implicit t ime of 30 Hz flic ker betw een the two groups was not significant (t=3.745,P=0.001). The difference of b/a value of maximal combination response was not obvious between the two groups ( t=0.215, P=0.831). Conclusions The development of retinal function is slower in preterm infants than that in full-term ones.

Citation: ZHOU Xiaohong,ZHAO Peiquan. Characteristics of electroretinograms in preterm infants. Chinese Journal of Ocular Fundus Diseases, 2008, 24(1): 20-22. doi: Copy