LI Jun 1 , LIU Fei 2
  • 1. Department of Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041,China2. Department of Nephrology, West China Hospital, Sichuan University,Chengdu,610041, China;
LI Jun, Email: jundream2003@yahoo.com.cn
Nonproliferative diabetic retinopathy; Evidence-based treatment
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Objective　 To summarize the available clinical evidence on the treatment of non-proliferative diabetic retinopathy (NPDR).
Methods　 Based on the basic methods and principles of evidence-based medicine, we searched and evaluated the NPDR-related evidence from the Cochrane Library(Issue 3,2007), PubMed (1966 to June 2007) and CBM(1979 to June 2007)
Results　 We finally identified 1 systematic review and 20 randomized controlled trials. Clinical evidence showed that critical glycemic control and blood pressure control were essential in the treatment of NPDR, which might delay the progression of retinopathy. The effectiveness of other therapeutic measures needed to be further investigated.
Conclusion　 NPDR is the early stage of diabetic retinopathy (DR). Relevant systematic reviews and high-quality randomized controlled trials have confirmed the effectiveness of critical control of blood glucose and blood pressure for NPDR. The effectiveness of other therapeutic measures needs to be confirmed by systematic reviews of high quality and rigorously designed randomized, multi-center and large-scale trials.

Citation： LI Jun,LIU Fei. Clinical Evidence on the Treatment of Non-proliferative Diabetic Retinopathy. Chinese Journal of Evidence-Based Medicine, 2007, 07(12): 894-898. doi: Copy