Effects of scleral buckling and vitrectomy for familial exudative vitreoretinopathy_Chinese Journal of Ocular Fundus Diseases

Authors：

WangXijuan ,  LiangJianhong , YinHong , LiXiaoxin

Department of Ophthalmology, Peking University People's Hospital; Key Laboratory of Vision Loss and Restoration (Peking University), Ministry of Education; Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing 100044, China;

Corresponding author：

LiangJianhong, Email: drjianhongliang@sina.com

Keywords：

Retinal diseases/congenital; Retinal diseases/surgery; Scleral buckling; Vitrectomy

DOI：

10.3760/cma.j.issn.1005-1015.2016.01.009

Video：

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Objective To observe the surgical effects of scleral buckling and vitrectomy for familial exudative vitreoretinopathy (FEVR). Methods 34 eyes of 27 patients with FEVR who underwent either scleral buckling or vitrectomy were enrolled in this study. There are stage 2B in 2 eyes (5.88%), stage 3B in 7 eyes (20.59%), stage 4A in 1 eye (2.94%), stage 4B in 16 eyes (47.06%), stage 5 in 8 eyes (23.53%). 5 eyes associated with rhegmatogenous retinal detachment. The surgical approaches had been chosen according to the disease stage, severity, extent and morphology of the proliferative membrane. 13 eyes (stage 2B in 2 eyes, 3B in 4 eyes, and 4 in 7 eyes) underwent scleral buckling and 21 eyes (stage 3B in 3 eyes, 4 in 10eyes, and 5 in 8 eyes) underwent vitreoretinal surgery. The main outcome measurement was the anatomic status of the macula, which was recorded as attached, partially attached or remain detached. The mean follow up was (18.00±14.61) months (range 4 to 60 months). Results Among 13 eyes received scleral buckling, the macula was attached in 2 eyes with stage 2B (15.38%), partially attached in 11 eyes (84.62%) including 4 eyes with stage 3B, 1 eye with stage 4A and 6 eyes with stage 4B. Among 21 eyes received vitrectomy, the macula was attached in 8 eyes (38.10%) including 2 eyes with stage 3B, 4 eyes with stage 4 and 2 eyes with stage 5; the macula was partially attached in 9 eyes (42.86%) inducing 4 eyes with stage 4 and 5 eyes with stage 5; the macula remained detached in 4 eyes (19.05%) including 1 eye with stage 3B, 2 eyes with stage 4 and 1 eye with stage 5. Conclusion If the surgical approaches were chosen based on the stage of FEVR and the severity, extent and morphology of the proliferative membrane, the surgery is effective and beneficial to FEVR patients.

Citation： WangXijuan, LiangJianhong, YinHong, LiXiaoxin. Effects of scleral buckling and vitrectomy for familial exudative vitreoretinopathy. Chinese Journal of Ocular Fundus Diseases, 2016, 32(1): 36-39. doi: 10.3760/cma.j.issn.1005-1015.2016.01.009 Copy

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1. Yamane T, Yokoi T, Nakayama Y, et al. Surgical outcomes of progressive tractional retinal detachment associated with familial exudative vitreoretinopathy[J]. Am J Ophthalmol, 2014, 158(5):1049-1055. DOI: 10.1016/j.ajo.2014.08.009.
2. 刘丽梅, 徐雁冰, 孙英, 等.巩膜扣带手术治疗家族性渗出性玻璃体视网膜病变合并孔源性视网膜脱离的疗效观察[J].中华眼底病杂志, 2015, 31(4):384-385. DOI:10.3760/cma.j.issn.1005-1015.2015.04.018.Liu LM, Xu YB, Sun Y, et al. Efficacy of scleral buckling surgery for patients of familial exudative vitreoretinopathy with rhegmatogenous retina detachment[J]. Chin J Ocul Fundus Dis, 2015, 31(4):384-385. DOI:10.3760/cma.j.issn.1005-1015.2015.04.018.
3. Schepens C. Non-rhegmatogenous retinal detachment from other causes[M]//Schepens CL, Hirose T. Retinal detachment and allied diseases.Burlington:Butterworth Heinemann, 2000:643-648.
4. Gilmour DF. Familial exudative vitreoretinopathy and related retinopathies[J]. Eye (Lond), 2015, 29(1):1-14. DOI: 10.1038/eye.2014.70.
5. Pendergast SD, Trese MT. Familial exudative vitreoretinopathy results of surgical management[J]. Ophthalmology, 1998, 105(6): 1015-1023.
6. Trese MT. Familial exudative vitreoretinopathy//Hartenett M. Pediatric retina. Philadelphia: Lippincott Williams & Wilkins, 2005: 425-428.
7. Mammoto A, Connor KM, Mammoto T, et al. A mechanosensitive transcriptional mechanism that controls angiogenesis[J]. Nature, 2009, 457(7233): 1103-1108. DOI: 10.1038/nature07765.

Chinese Journal of Ocular Fundus Diseases

Effects of scleral buckling and vitrectomy for familial exudative vitreoretinopathy

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