Better understanding retinal and choroidal vascular diseases with optical coherence tomography angiography_Chinese Journal of Ocular Fundus Diseases

Authors：

 WangMin

Department of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai 200031, China;

Corresponding author：

WangMin, Email: wangmin83@yahoo.com

Keywords：

Retinal diseases/diagnosis; Choroid diseases/diagnosis; Tomography,optical coherence; Editorial

DOI：

10.3760/cma.j.issn.1005-1015.2016.04.003

Video：

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Optical coherence tomography angiography (OCTA) is a new and non-invasive imaging technique that is able to detect blood flow signal in the retina and the choroid within seconds. OCTA is different from the traditional angiography methods. The major advantages of OCTA are that it can observe blood flow signal in different layers of the retina and the choroid without injecting any dye, provide blood flow information that traditional angiography cannot provide, and enrich pathophysiological knowledge of the retinal and choroidal vascular diseases., which help us to make an accurate diagnosis and efficient evaluation of these diseases. However there is a large upgrade potential either on OCTA technique itself or on clinical application of OCTA. We need to fully understand the advantage and disadvantage, and differences of OCTA and traditional angiography. We also need to know how to interpret the result of OCTA. With that we could make a fast diagnosis in a non-invasive way and improve our knowledge of the retinal and choroidal vascular diseases.

Citation： WangMin. Better understanding retinal and choroidal vascular diseases with optical coherence tomography angiography. Chinese Journal of Ocular Fundus Diseases, 2016, 32(4): 353-356. doi: 10.3760/cma.j.issn.1005-1015.2016.04.003 Copy

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6.	Yannuzzi LA, Slakter JS, Sorenson JA, et al. Digital indocyanine green videoangiography and choroidal neovascularization[J]. Retina, 1992,12(3):191-223.
7.	Novotny HR, Alvis DL. A method of photographing fluorescence in circulating blood in the human retina[J]. Circulation, 1961,24:82-86.
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9.	Kuehlewein L, Bansal M, Lenis TL, et al. Optical coherence tomography angiography of type 1 neovascularization in age-related macular degeneration[J]. Am J Ophthalmol, 2015,160(4):739-748.DOI:10.1016/j.ajo.2015.06.030.
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12.	Coscas G, Lupidi M, Coscas F, et al. Optical coherence tomography angiography during follow-up:qualitative and quantitative analysis of mixed type Ⅰ and Ⅱ choroidal neovascularization after vascular endothelial growth factor trap therapy[J]. Ophthalmic Res, 2015,54(2):57-63.DOI:10.1159/000433547.
13.	Inoue M, Balaratnasingam C, Freund KB. Optical coherence tomography angiography of polypoidal choroidal vasculopathy and polypoidal choroidal neovascularization[J]. Retina, 2015,35(11):2265-2274.DOI:10.1097/IAE.0000000000000777.
14.	Ishibazawa A, Nagaoka T, Takahashi A, et al. Optical coherence tomography angiography in diabetic retinopathy:a prospective pilot study[J]. Am J Ophthalmol, 2015,160(1):35-44.DOI:10.1016/j.ajo.2015.04.021.
15.	Couturier A, Mane V, Bonnin S, et al. Capillary plexus anomalies in diabetic retinopathy on optical coherence tomography angiography[J]. Retina, 2015,35(11):2384-2391.DOI:10.1097/IAE.0000000000000859.
16.	王敏, 叶晓峰. 视网膜血管性疾病[M]//王敏, 徐格致, 孙兴怀, 等. OCT血管成像和en face OCT图谱. 上海:复旦大学出版社, 2015:97-108.Wang M,Ye XF.Retinal vasclar disease[M]//Wang M,Xu GZ,Sun XH, et al.The atlas of OCT angiography and en face OCT.Shanghai:Fudan University Press,2015:97-108.
17.	Rispoli M, Savastano MC, Lumbroso B. Capillary network anomalies in branch retinal vein occlusion on optical coherence tomography angiography[J]. Retina, 2015,35(11):2332-2338.DOI:10.1097/IAE.0000000000000845.
18.	Suzuki N, Hirano Y, Yoshida M, et al. Microvascular abnormalities on optical coherence tomography angiography in macular edema associated with branch retinal vein occlusion[J]. Am J Ophthalmol, 2016,161:126-132.DOI:10.1016/j.ajo.2015.09.038.

1. Jia Y,Tan O,Tokayer J,et al.Split-spectrum amplitude-decorrelation angiorgraphy with optical coherence tomography[J]. Opt Express, 2012,20(4):4710-4725.DOI:10.1364/OE.20.004710.
2. Do DV, Gower EW, Cassard SD, et al. Detection of new-onset choroidal neovascularization using optical coherence tomography:the AMD DOC Study[J]. Ophthalmology, 2012,119(4):771-778. DOI:10.1016/j.ophtha.2011.10.019.
3. Kotsolis AI, Killian FA, Ladas ID, et al. Fluorescein angiography and optical coherence tomography concordance for choroidal neovascularisation in multifocal choroidtis[J]. Br J Ophthalmol, 2010,94(11):1506-1508.DOI:10.1136/bjo.2009.159913.
4. Yannuzzi LA, Rohrer KT, Tindel LJ, et al. Fluorescein angiography complication survey[J]. Ophthalmology, 1986,93(5):611-617.
5. Butner RW, McPherson AR. Adverse reactions in intravenous fluorescein angiography[J]. Ann Ophthalmol, 1983,15(11):1084-1086.
6. Yannuzzi LA, Slakter JS, Sorenson JA, et al. Digital indocyanine green videoangiography and choroidal neovascularization[J]. Retina, 1992,12(3):191-223.
7. Novotny HR, Alvis DL. A method of photographing fluorescence in circulating blood in the human retina[J]. Circulation, 1961,24:82-86.
8. Savastano MC, Lumbroso B, Rispoli M. In vivo characterization of retinal vascularization morphology using optical coherence tomography angiography[J]. Retina, 2015,35(11):2196-2203.DOI:10.1097/IAE.0000000000000635.
9. Kuehlewein L, Bansal M, Lenis TL, et al. Optical coherence tomography angiography of type 1 neovascularization in age-related macular degeneration[J]. Am J Ophthalmol, 2015,160(4):739-748.DOI:10.1016/j.ajo.2015.06.030.
10. El AA, Cohen SY, Semoun O, et al. Type 2 neovascularization secondary to age-related macular degeneration imaged by optical coherence tomography angiography[J]. Retina, 2015,35(11):2212-2218.DOI:10.1097/IAE.0000000000000773.
11. Huang D, Jia Y, Rispoli M, et al. Optical coherence tomography angiographyof time course of choroidal neovascularization in response to anti-angiogentic treatment[J]. Retina, 2015,35(11):2260-2264.DOI:10.1097/IAE.0000000000000846.
12. Coscas G, Lupidi M, Coscas F, et al. Optical coherence tomography angiography during follow-up:qualitative and quantitative analysis of mixed type Ⅰ and Ⅱ choroidal neovascularization after vascular endothelial growth factor trap therapy[J]. Ophthalmic Res, 2015,54(2):57-63.DOI:10.1159/000433547.
13. Inoue M, Balaratnasingam C, Freund KB. Optical coherence tomography angiography of polypoidal choroidal vasculopathy and polypoidal choroidal neovascularization[J]. Retina, 2015,35(11):2265-2274.DOI:10.1097/IAE.0000000000000777.
14. Ishibazawa A, Nagaoka T, Takahashi A, et al. Optical coherence tomography angiography in diabetic retinopathy:a prospective pilot study[J]. Am J Ophthalmol, 2015,160(1):35-44.DOI:10.1016/j.ajo.2015.04.021.
15. Couturier A, Mane V, Bonnin S, et al. Capillary plexus anomalies in diabetic retinopathy on optical coherence tomography angiography[J]. Retina, 2015,35(11):2384-2391.DOI:10.1097/IAE.0000000000000859.
16. 王敏, 叶晓峰. 视网膜血管性疾病[M]//王敏, 徐格致, 孙兴怀, 等. OCT血管成像和en face OCT图谱. 上海:复旦大学出版社, 2015:97-108.Wang M,Ye XF.Retinal vasclar disease[M]//Wang M,Xu GZ,Sun XH, et al.The atlas of OCT angiography and en face OCT.Shanghai:Fudan University Press,2015:97-108.
17. Rispoli M, Savastano MC, Lumbroso B. Capillary network anomalies in branch retinal vein occlusion on optical coherence tomography angiography[J]. Retina, 2015,35(11):2332-2338.DOI:10.1097/IAE.0000000000000845.
18. Suzuki N, Hirano Y, Yoshida M, et al. Microvascular abnormalities on optical coherence tomography angiography in macular edema associated with branch retinal vein occlusion[J]. Am J Ophthalmol, 2016,161:126-132.DOI:10.1016/j.ajo.2015.09.038.

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