Construct a diagnostic thinking for intraocular inflammatory diseases_Chinese Journal of Ocular Fundus Diseases

Authors：

 Zhao Mingwei , Miao Heng

Department of Ophthalmology, Peking University People’s Hospital Eye Diseases and Optometry Institute, Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases College of Optometry, Peking University Health Science Center, Beijing 100044, China;

Corresponding author：

Zhao Mingwei, Email: dr_zhaomingwei@163.com

Keywords：

Endophthalmitis/diagnosis; Editorial

DOI：

10.3760/cma.j.issn.1005-1015.2019.05.002

Video：

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Abstract Full text Figures/Tables Video References Cited by

The etiology of intraocular inflammatory disease and its diagnosis is complicated. Currently available and newly emerging systemic and ocular examinations are of important to determine etiology of intraocular inflammatory disorders. But there also exists multiple misunderstanding, and the strategy of their application is not well defined, or even exaggerated. Unprincipled or randomly selection of auxiliary examination would not help for etiology determination, but bring unnecessary pain and economic burden to patients. Establishment of diagnosis thinking of intraocular inflammatory disease is helpful to standardize the diagnosis process of the disease, improve the diagnostic efficiency, and relief patients from the pain and financial burden that caused by too many useless examinations.

Citation： Zhao Mingwei, Miao Heng. Construct a diagnostic thinking for intraocular inflammatory diseases. Chinese Journal of Ocular Fundus Diseases, 2019, 35(5): 432-434. doi: 10.3760/cma.j.issn.1005-1015.2019.05.002 Copy

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4.	Gupta V, Shoughy SS, Mahajan S, et al. Clinics of ocular tuberculosis[J]. Ocul Immunol Inflamm, 2015, 23(1): 14-24. DOI: 10.3109/09273948.2014.986582.
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6.	Hadjadj J, Dechartres A, Chapron T, et al. Relevance of diagnostic investigations in patients with uveitis: retrospective cohort study on 300 patients[J]. Autoimmun Rev, 2017, 16(5): 504-511. DOI: 10.1016/j.autrev.2017.03.006.
7.	Urzua CA, Liberman P, Abuauad S, et al. Evaluation of the accuracy of T-SPOT. TB for the diagnosis of ocular tuberculosis in a BCG-vaccinated, non-endemic population[J]. Ocul Immunol Inflamm, 2017, 25(4): 455-459. DOI: 10.3109/09273948.2015.1135965.
8.	Bhagya S, Lalitha P, Kumar AL, et al. Polymerase chain reaction and its correlation with clinical features and treatment response in tubercular uveitis[J]. Ocul Immunol Inflamm, 2018, 26(6): 845-852. DOI: 10.1080/09273948.2017.1287925.
9.	Mehta M, Rasheed RA, Duker J, et al. Vitreous evaluation: a diagnostic challenge[J]. Ophthalmology, 2015, 122(3): 531-537. DOI: 10.1016/j.ophtha.2014.09.016.
10.	de Groot-Mijnes JD, de Visser L, Zuurveen S, et al. Identification of new pathogens in the intraocular fluid of patients with uveitis[J]. Am J Ophthalmol, 2010, 150(5): 628-636. DOI: 10.1016/j.ajo.2010.05.015.
11.	Sugita S, Ogawa M, Shimizu N, et al. Use of a comprehensive polymerase chain reaction system for diagnosis of ocular infectious diseases[J]. Ophthalmology, 2013, 120(9): 1761-1768. DOI: 10.1016/j.ophtha.2013.02.020.
12.	Westeneng AC, Rothova A, de Boer JH, et al. Infectious uveitis in immunocompromised patients and the diagnostic value of polymerase chain reaction and Goldmann-Witmer coefficient in aqueous analysis[J]. Am J Ophthalmol, 2007, 144(5): 781-785. DOI: 10.1016/j.ajo.2007.06.034.
13.	Sugita S, Kamoi K, Ogawa M, et al. Detection of Candida and Aspergillus species DNA using broad-range real-time PCR for fungal endophthalmitis[J]. Graefe’s Arch Clin Exp Ophthalmol, 2012, 250(3): 391-398. DOI: 10.1007/s00417-011-1819-1.

1. Miserocchi E, Fogliato G, Modorati G, et al. Review on the worldwide epidemiology of uveitis[J]. Eur J Ophthalmol, 2013, 23(5): 705-717. DOI: 10.5301/ejo.5000278.
2. Chen EJ, Bin Ismail MA, Mi H, et al. Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) - report 1: epidemiology and classification[J]. Ocul Immunol Inflamm, 2018, 26(5): 732-746. DOI: 10.1080/09273948.2016.1249376.
3. Dutta Majumder P, Chen EJ, Shah J, et al. Ocular syphilis: an update[J]. Ocul Immunol Inflamm, 2019, 27(1): 117-125. DOI: 10.1080/09273948.2017.1371765.
4. Gupta V, Shoughy SS, Mahajan S, et al. Clinics of ocular tuberculosis[J]. Ocul Immunol Inflamm, 2015, 23(1): 14-24. DOI: 10.3109/09273948.2014.986582.
5. de Parisot A, Kodjikian L, Errera MH, et al. Randomized controlled trial evaluating a standardized strategy for uveitis etiologic diagnosis (ULISSE)[J]. Am J Ophthalmol, 2017, 178: 176-185. DOI: 10.1016/j.ajo.2017.03.029.
6. Hadjadj J, Dechartres A, Chapron T, et al. Relevance of diagnostic investigations in patients with uveitis: retrospective cohort study on 300 patients[J]. Autoimmun Rev, 2017, 16(5): 504-511. DOI: 10.1016/j.autrev.2017.03.006.
7. Urzua CA, Liberman P, Abuauad S, et al. Evaluation of the accuracy of T-SPOT. TB for the diagnosis of ocular tuberculosis in a BCG-vaccinated, non-endemic population[J]. Ocul Immunol Inflamm, 2017, 25(4): 455-459. DOI: 10.3109/09273948.2015.1135965.
8. Bhagya S, Lalitha P, Kumar AL, et al. Polymerase chain reaction and its correlation with clinical features and treatment response in tubercular uveitis[J]. Ocul Immunol Inflamm, 2018, 26(6): 845-852. DOI: 10.1080/09273948.2017.1287925.
9. Mehta M, Rasheed RA, Duker J, et al. Vitreous evaluation: a diagnostic challenge[J]. Ophthalmology, 2015, 122(3): 531-537. DOI: 10.1016/j.ophtha.2014.09.016.
10. de Groot-Mijnes JD, de Visser L, Zuurveen S, et al. Identification of new pathogens in the intraocular fluid of patients with uveitis[J]. Am J Ophthalmol, 2010, 150(5): 628-636. DOI: 10.1016/j.ajo.2010.05.015.
11. Sugita S, Ogawa M, Shimizu N, et al. Use of a comprehensive polymerase chain reaction system for diagnosis of ocular infectious diseases[J]. Ophthalmology, 2013, 120(9): 1761-1768. DOI: 10.1016/j.ophtha.2013.02.020.
12. Westeneng AC, Rothova A, de Boer JH, et al. Infectious uveitis in immunocompromised patients and the diagnostic value of polymerase chain reaction and Goldmann-Witmer coefficient in aqueous analysis[J]. Am J Ophthalmol, 2007, 144(5): 781-785. DOI: 10.1016/j.ajo.2007.06.034.
13. Sugita S, Kamoi K, Ogawa M, et al. Detection of Candida and Aspergillus species DNA using broad-range real-time PCR for fungal endophthalmitis[J]. Graefe’s Arch Clin Exp Ophthalmol, 2012, 250(3): 391-398. DOI: 10.1007/s00417-011-1819-1.

Chinese Journal of Ocular Fundus Diseases

Construct a diagnostic thinking for intraocular inflammatory diseases

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