To simplify the production process of intraocular lens (IOL) and to solve the problem of lacking adjustable ability, we proposed a novel soft IOL with large-scale adjustable ability and rigid haptics based on heat-assisted method, and gravity-assisted method. Polydimethylsiloxane (PDMS) and rigid material——polymethyl methacrylate (PMMA) were used as the materials for fabricating optical lens (PDMS) and haptics (PDMS and PMMA) through changing the weight ratio of the solution. A lens-smartphone microscopy system was established to replace the traditional digital microscopy to measure the tiny displacements and shape changes. The PDMS lens has excellent optical property through an experiment in which the maximum optical power was around 273.2 D. Experimental results indicated that the maximum optical power of PMMA IOL was 129.3 D, and that in PDMS IOL, however, was only 56.0 D. Thus, the rigid PMMA-IOL has a larger adjustable range. The production process of PDMS was mold-free, rapid, real-time, and highly repeatable and there was no need for a rigorous experimental environment either. This creative processing technology reduced the manufacturing steps from which an optical lens with high transmittance and high resolution, as well as hatics with accurate dimensions, were obtained. The rigidity of haptics affected more intensely than other factors did for improving the pre-displacement and changing the appearance of PDMS lens. Even though the rigidity of PMMA haptics is large enough for accommodating, there are many drawbacks during manufacturing. It is unavailable to rapid fabricate IOL using PMMA. Thus, further work will be required to alter the weight ratio of PDMS material, increase the rigidity, and enhance the adjustable ability of PDMS IOL.

Citation： DU Qiuyue, YU Yueqing. Fabrication and Performance Study of Polydimethylsiloxane Intraocular Lens. Journal of Biomedical Engineering, 2016, 33(5): 896-902. doi: 10.7507/1001-5515.20160145 Copy