Development of Automatic Preparation Device of Sclerosing Foam Based on Tessari Method_Journal of Biomedical Engineering

Authors：

WANHao ¹ , BAITaoping ² , JIANGWentao ² , HUANGXuejin ² ,  ZHAOWu ¹

1. School of Manufacturing Science and Engineering, Sichuan University, Chengdu 610065, China;
2. Department of Engineering Mechanics, Biomechanical Engineering Laboratory, Sichuan University, Chengdu 610065, China;

Corresponding author：

ZHAOWu, Email: zhaowu@scu.edu.cn

Keywords：

sclerosing foam; Tessari method; automatic preparation device; pushing speed

DOI：

10.7507/1001-5515.20160188

Video：

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Based on the principle of manual preparation of sclerosing foam with Tessari method, using the analysis of user requirements and combining it with theory of mechanics, we designed an automatic equipment. The device could be used to replace the manual operation, and could overcome the shortcomings of manual sclerosing foam preparation, such as the difficulty in controlling of pushing speed and stroke and poor reproducibility. This automatic device has the functions of adjustable pushing speed, pushing frequency, pushing stroke and is suitable for a variety of different types of syringes. It can not only provide quantitative parameters for the study of foam properties, but also be used for the standardization of clinical sclerosing foam. The experimental study on "the effect of pushing speed on the stability of foam" was carried out with using the device, and the experimental results were quite satisfactory.

Citation： WANHao, BAITaoping, JIANGWentao, HUANGXuejin, ZHAOWu. Development of Automatic Preparation Device of Sclerosing Foam Based on Tessari Method. Journal of Biomedical Engineering, 2016, 33(6): 1191-1195. doi: 10.7507/1001-5515.20160188 Copy

1.	BREU F X, GUGGENBICHLER S. European consensus meeting on foam sclerotherapy, April, 4-6, 2003, tegernsee, Germany[J]. Dermatol Surg, 2004, 30(5): 709-717; discussion 717.
2.	BERGAN J. Sclerotherapy: a truly minimally invasive technique[J]. Perspect Vasc Surg Endovasc Ther, 2008, 20(1): 70-72.
3.	TESSARI L, CAVEZZI A, FRULLINI A. Preliminary experience with a new sclerosing foam in the treatment of varicose veins[J]. Dermatol Surg, 2001, 27(1): 58-60.
4.	BREU F X, GUGGENBICHLER S, WOLLMANN J C. 2nd European consensus meeting on foam sclerotherapy, 28-30 April 2006,Tegernsee,Germany[J]. Vasa, 2008. 37 Suppl 71: 1-29.
5.	GLOVICZKI P, COMEROTA A J, DALSING M C, et al. The care of patients with varicose veins and associated chronic venous diseases: clinical practice guidelines of the Society for Vascular Surgery and the American Venous Forum[J]. J Vasc Surg, 2011, 53(5 Suppl): 2S-48S.
6.	JIA X, MOWATT G, BURR J M, et al. Systematic review of foam sclerotherapy for varicose veins[J]. Br J Surg, 2007, 94(8): 925-936.
7.	WEITZ-TUORETMAA A, RAUTIO R, VALKILA J, et al. Efficacy of OK-432 sclerotherapy in treatment of lymphatic malformations: long-term follow-up results[J]. Eur Arch Otorhinolaryngol, 2014, 271(2): 385-390.
8.	RIAL R, HERVAS L S, MONUX G, et al. Polidocanol foam stability in terms of its association with glycerin[J]. Phlebology, 2014, 29(5): 304-309.
9.	CEULEN R, JAGTMAN E A, SOMMER A, et al. Blocking the saphenofemoral junction during Ultrasound-Guided foam sclerotherapy-assessment of a presumed safety-measure procedure[J]. Eur J Vasc Endovasc Surg, 2010, 40(6): 772-776.
10.	CAMERON E, CHEN T, CONNOR D E, et al. Sclerosant foam structure and stability is strongly influenced by liquid air fraction[J]. Eur J Vasc Endovasc Surg, 2013, 46(4): 488-494.
11.	HESSE G, BREU F X, KUSCHMANN A, et al. Sclerotherapy using air- or CO₂-O₂-foam. Post-approval study[J]. Phlebologie, 2012, 41(2): 77-88.

1. BREU F X, GUGGENBICHLER S. European consensus meeting on foam sclerotherapy, April, 4-6, 2003, tegernsee, Germany[J]. Dermatol Surg, 2004, 30(5): 709-717; discussion 717.
2. BERGAN J. Sclerotherapy: a truly minimally invasive technique[J]. Perspect Vasc Surg Endovasc Ther, 2008, 20(1): 70-72.
3. TESSARI L, CAVEZZI A, FRULLINI A. Preliminary experience with a new sclerosing foam in the treatment of varicose veins[J]. Dermatol Surg, 2001, 27(1): 58-60.
4. BREU F X, GUGGENBICHLER S, WOLLMANN J C. 2nd European consensus meeting on foam sclerotherapy, 28-30 April 2006,Tegernsee,Germany[J]. Vasa, 2008. 37 Suppl 71: 1-29.
5. GLOVICZKI P, COMEROTA A J, DALSING M C, et al. The care of patients with varicose veins and associated chronic venous diseases: clinical practice guidelines of the Society for Vascular Surgery and the American Venous Forum[J]. J Vasc Surg, 2011, 53(5 Suppl): 2S-48S.
6. JIA X, MOWATT G, BURR J M, et al. Systematic review of foam sclerotherapy for varicose veins[J]. Br J Surg, 2007, 94(8): 925-936.
7. WEITZ-TUORETMAA A, RAUTIO R, VALKILA J, et al. Efficacy of OK-432 sclerotherapy in treatment of lymphatic malformations: long-term follow-up results[J]. Eur Arch Otorhinolaryngol, 2014, 271(2): 385-390.
8. RIAL R, HERVAS L S, MONUX G, et al. Polidocanol foam stability in terms of its association with glycerin[J]. Phlebology, 2014, 29(5): 304-309.
9. CEULEN R, JAGTMAN E A, SOMMER A, et al. Blocking the saphenofemoral junction during Ultrasound-Guided foam sclerotherapy-assessment of a presumed safety-measure procedure[J]. Eur J Vasc Endovasc Surg, 2010, 40(6): 772-776.
10. CAMERON E, CHEN T, CONNOR D E, et al. Sclerosant foam structure and stability is strongly influenced by liquid air fraction[J]. Eur J Vasc Endovasc Surg, 2013, 46(4): 488-494.
11. HESSE G, BREU F X, KUSCHMANN A, et al. Sclerotherapy using air- or CO₂-O₂-foam. Post-approval study[J]. Phlebologie, 2012, 41(2): 77-88.

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