The effect of preload and support’s stiffness on the performance of round window stimulation: a numerical analysis_Journal of Biomedical Engineering

Authors：

ZHANG Hu ¹ ,  LIU Houguang ¹ , ZHAO Yu ¹ , RAO Zhushi ² , YANG Jianhua ¹ , WANG Wenbo ¹

1. School of Mechatronic Engineering, China University of Mining and Technology, Xuzhou, Jiangsu 221116, P.R.China;
2. State Key Laboratory of Mechanical System and Vibration, Shanghai Jiao Tong University, Shanghai 200240, P.R.China;

Corresponding author：

LIU Houguang, Email: liuhg@cumt.edu.cn

Keywords：

middle ear implants; preload; support’s stiffness; round window; finite element analysis

DOI：

10.7507/1001-5515.201611039

Video：

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To investigate the influence of the preload and supporting stiffness on the hearing compensation performance of round window stimulation, a coupling finite model composed of a human ear, an actuator and a support was established. This model was constructed based on a complete set of micro-computed tomography (Micro-CT) images of a healthy adult’s right ear by reverse engineering technology. The validity of the model was verified by comparing the model’s calculated results with experimental data. Based on this model, we applied different amplitude preloads on the actuator, and changed the support’s stiffness. Then, the influences of the actuator’s preload and the support’s stiffness were analyzed by comparing the corresponding displacements of the basilar membrane. The results show that after applying a preload on the actuator, its hearing compensation performance was increased at the middle and high frequencies, but was deteriorated at low frequencies; besides, compared with using the fascia as the actuator’s support in clinical practice, utilizing the titanium alloy to fabricate the support would enhance the hearing compensation performance of the round window stimulation in the whole frequency range.

Citation： ZHANG Hu, LIU Houguang, ZHAO Yu, RAO Zhushi, YANG Jianhua, WANG Wenbo. The effect of preload and support’s stiffness on the performance of round window stimulation: a numerical analysis. Journal of Biomedical Engineering, 2018, 35(2): 191-197. doi: 10.7507/1001-5515.201611039 Copy

1.	第二次全国残疾人抽样调查办公室. 第二次全国残疾人抽样调查资料. 北京: 中国统计出版社, 2007.
2.	Moore B C J. Cochlear hearing loss: physiological, psychological and technical issues. 2nd ed. Chichester: John Wiley & Sons, 2007: 1-332.
3.	Gan R Z, Dai C, Wang X, et al. A totally implantable hearing system—design and function characterization in 3D computational model and temporal bones. Hear Res, 2010, 263(1/2): 138-144.
4.	Liu Houguang, Rao Zhushi, Huang Xinsheng, et al. An incus-body driving type piezoelectric middle ear implant design and evaluation in 3D computational model and temporal bone. Scientific World Journal, 2014, 2014(4): 121624.
5.	Colletti V, Soli S, Carner M, et al. Treatment of mixed hearing losses via implantation of a vibratory transducer on the round window. Int J Audiol, 2006, 45(10): 600-608.
6.	Sprinzl G, Wolf-Magele A, Schnabl J, et al. The active middle ear implant for the rehabilitation of sensorineural, mixed and conductive hearing losses. Laryngorhinootologie, 2011, 90(9): 560-572.
7.	Arnold A, Stieger C, Candreia C, et al. Factors improving the vibration transfer of the floating mass transducer at the round window. Otol Neurotol, 2010, 31(1): 122-128.
8.	Zhang X, Gan Rong. A comprehensive model of human ear for analysis of implantable hearing devices. IEEE Trans Biomed Eng, 2011, 58(10): 3024-3027.
9.	Maier H, Salcher R, Schwab B, et al. The effect of static force on round window stimulation with the direct acoustic cochlea stimulator. Hear Res, 2013, 301(7): 115-124.
10.	Lupo J E, Koka K, Hyde B J, et al. Physiological assessment of active middle ear implant coupling to the round window in Chinchilla lanigera. Otolaryngol Head Neck Surg, 2011, 145(4): 641-647.
11.	田佳彬, 饶柱石, 塔娜, 等. 人工中耳悬浮式压电振子的优化设计. 振动与冲击, 2015, 34(5): 135-140.
12.	Zwislocki J. Analysis of the middle-ear function. Part Ⅰ: input impedance. J Acoust Soc Am, 1962, 34(9B): 1514-1523.
13.	王学林. 蜗窗激励与外耳道激励产生的耳蜗压力差的比较分析. 生物医学工程学杂志, 2012, 29(6): 1109-1113.
14.	Tian Jiabin, Huang Xinsheng, Rao Zhushi, et al. Finite element analysis of the effect of actuator coupling conditions on round window stimulation. J Mech Med Biol, 2015, 15(4): 1550048.
15.	王应丰, 沈高飞, 塔娜, 等. 声桥系统压电植入振子力学建模及参数优化. 振动与冲击, 2009, 28(3): 108-111.
16.	刘后广, 塔娜, 饶柱石. 新型人工中耳压电振子设计. 振动与冲击, 2011, 30(7): 112-115, 126.
17.	王学林, 胡于进. 蜗窗激励评价的有限元计算模型研究. 力学学报, 2012, 44(3): 622-630.
18.	Békésy G V. Experiments in hearing. New York: McGraw-Hill, 1960.
19.	Kringlebotn M, Gundersen T, Krokstad A, et al. Noise-induced hearing losses. Can they be explained by basilar membrane movement?. Acta Otolaryngol Suppl, 1979, 360(sup360): 98-101.
20.	Gundersen T, Skarstein O, Sikkeland T. A study of the vibration of the basilar membrane in human temporal bone preparations by the use of the Mössbauer effect. Acta Otolaryngol, 1978, 86(3/4): 225-232.
21.	Puria S, Peake W, Rosowski J. Sound-pressure measurements in the cochlear vestibule of human-cadaver ears. J Acoust Soc Am, 1997, 101(5 Pt 1): 2754-2770.
22.	Aibara R, Welsh J, Puria S, et al. Human middle-ear sound transfer function and cochlear input impedance. Hear Res, 2001, 152(1/2): 100-109.
23.	Ghasemi-Nejhad M N, Pourjalali S, Uyema M, et al. Finite element method for active vibration suppression of smart composite structures using piezoelectric materials. J Thermoplast Compos Mater, 2006, 19(3): 309-352.
24.	刘后广. 新型人工中耳压电振子听力补偿的理论与实验研究. 上海: 上海交通大学, 2011.
25.	Laursen W. Breaking the sound barrier[cochlear implants]. Engineering & Technology, 2006, 1(3): 38-41.
26.	Hong E P, Kim M K, Park I Y, et al. Vibration modeling and design of piezoelectric floating mass transducer for implantable middle ear hearing devices. IEICE Transactions on Fundamentals of Electronics Communications and Computer Sciences, 2007, 90(8): 1620-1627.
27.	Ma J, Yao W. Research on the distribution of pressure field on the basilar membrane in the passive spiral cochlea. J Mech Med Biol, 2014, 14(04): 1450061.
28.	Sun Q, Gan R Z, Chang K H, et al. Computer-integrated finite element modeling of human middle ear. Biomech Model Mechanobiol, 2002, 1(2): 109-122.

1. 第二次全国残疾人抽样调查办公室. 第二次全国残疾人抽样调查资料. 北京: 中国统计出版社, 2007.
2. Moore B C J. Cochlear hearing loss: physiological, psychological and technical issues. 2nd ed. Chichester: John Wiley & Sons, 2007: 1-332.
3. Gan R Z, Dai C, Wang X, et al. A totally implantable hearing system—design and function characterization in 3D computational model and temporal bones. Hear Res, 2010, 263(1/2): 138-144.
4. Liu Houguang, Rao Zhushi, Huang Xinsheng, et al. An incus-body driving type piezoelectric middle ear implant design and evaluation in 3D computational model and temporal bone. Scientific World Journal, 2014, 2014(4): 121624.
5. Colletti V, Soli S, Carner M, et al. Treatment of mixed hearing losses via implantation of a vibratory transducer on the round window. Int J Audiol, 2006, 45(10): 600-608.
6. Sprinzl G, Wolf-Magele A, Schnabl J, et al. The active middle ear implant for the rehabilitation of sensorineural, mixed and conductive hearing losses. Laryngorhinootologie, 2011, 90(9): 560-572.
7. Arnold A, Stieger C, Candreia C, et al. Factors improving the vibration transfer of the floating mass transducer at the round window. Otol Neurotol, 2010, 31(1): 122-128.
8. Zhang X, Gan Rong. A comprehensive model of human ear for analysis of implantable hearing devices. IEEE Trans Biomed Eng, 2011, 58(10): 3024-3027.
9. Maier H, Salcher R, Schwab B, et al. The effect of static force on round window stimulation with the direct acoustic cochlea stimulator. Hear Res, 2013, 301(7): 115-124.
10. Lupo J E, Koka K, Hyde B J, et al. Physiological assessment of active middle ear implant coupling to the round window in Chinchilla lanigera. Otolaryngol Head Neck Surg, 2011, 145(4): 641-647.
11. 田佳彬, 饶柱石, 塔娜, 等. 人工中耳悬浮式压电振子的优化设计. 振动与冲击, 2015, 34(5): 135-140.
12. Zwislocki J. Analysis of the middle-ear function. Part Ⅰ: input impedance. J Acoust Soc Am, 1962, 34(9B): 1514-1523.
13. 王学林. 蜗窗激励与外耳道激励产生的耳蜗压力差的比较分析. 生物医学工程学杂志, 2012, 29(6): 1109-1113.
14. Tian Jiabin, Huang Xinsheng, Rao Zhushi, et al. Finite element analysis of the effect of actuator coupling conditions on round window stimulation. J Mech Med Biol, 2015, 15(4): 1550048.
15. 王应丰, 沈高飞, 塔娜, 等. 声桥系统压电植入振子力学建模及参数优化. 振动与冲击, 2009, 28(3): 108-111.
16. 刘后广, 塔娜, 饶柱石. 新型人工中耳压电振子设计. 振动与冲击, 2011, 30(7): 112-115, 126.
17. 王学林, 胡于进. 蜗窗激励评价的有限元计算模型研究. 力学学报, 2012, 44(3): 622-630.
18. Békésy G V. Experiments in hearing. New York: McGraw-Hill, 1960.
19. Kringlebotn M, Gundersen T, Krokstad A, et al. Noise-induced hearing losses. Can they be explained by basilar membrane movement?. Acta Otolaryngol Suppl, 1979, 360(sup360): 98-101.
20. Gundersen T, Skarstein O, Sikkeland T. A study of the vibration of the basilar membrane in human temporal bone preparations by the use of the Mössbauer effect. Acta Otolaryngol, 1978, 86(3/4): 225-232.
21. Puria S, Peake W, Rosowski J. Sound-pressure measurements in the cochlear vestibule of human-cadaver ears. J Acoust Soc Am, 1997, 101(5 Pt 1): 2754-2770.
22. Aibara R, Welsh J, Puria S, et al. Human middle-ear sound transfer function and cochlear input impedance. Hear Res, 2001, 152(1/2): 100-109.
23. Ghasemi-Nejhad M N, Pourjalali S, Uyema M, et al. Finite element method for active vibration suppression of smart composite structures using piezoelectric materials. J Thermoplast Compos Mater, 2006, 19(3): 309-352.
24. 刘后广. 新型人工中耳压电振子听力补偿的理论与实验研究. 上海: 上海交通大学, 2011.
25. Laursen W. Breaking the sound barrier[cochlear implants]. Engineering & Technology, 2006, 1(3): 38-41.
26. Hong E P, Kim M K, Park I Y, et al. Vibration modeling and design of piezoelectric floating mass transducer for implantable middle ear hearing devices. IEICE Transactions on Fundamentals of Electronics Communications and Computer Sciences, 2007, 90(8): 1620-1627.
27. Ma J, Yao W. Research on the distribution of pressure field on the basilar membrane in the passive spiral cochlea. J Mech Med Biol, 2014, 14(04): 1450061.
28. Sun Q, Gan R Z, Chang K H, et al. Computer-integrated finite element modeling of human middle ear. Biomech Model Mechanobiol, 2002, 1(2): 109-122.

Journal of Biomedical Engineering

The effect of preload and support’s stiffness on the performance of round window stimulation: a numerical analysis

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