Efficacy and Safety of Magnesium Sulfate Preparations and Macrogol 4000 on New-onset Constipation during Hospitalization among Patients with Coronary Heart Disease_West China Medical Journal

Authors：

Department of Cardiovascular Medicine, People’s Hospital of Deyang City, Deyang, Sichuan 618000, P. R. China;

Corresponding author：

Keywords：

新发便秘; 硫酸镁; 聚乙二醇4000; 冠心病

DOI：

10.7507/1002-0179.20130235

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

目的　对比研究口服硫酸镁与聚乙二醇4000对老年冠心病新发便秘患者的通便效果及安全性。方法　 2010年10月－2012年4月将158例冠心病新发便秘老年患者按入院单双号时间随机分为两组，试验组88例患者口服硫酸镁，对照组70例服用聚乙二醇4000 散剂，观察两组患者服药后排便时间、排便效果及服药后不良反应。结果　两组排便时间比较，试验组67例（76.14%）患者在服药6 h内开始排便，对照组则仅有35例（50.00%）在该时间段排便，试验组人均排便量及总有效率优于对照组。结论　硫酸镁治疗老年冠心病新发便秘疗效确切，不良反应低，不失为一种临床解除新发便秘安全、有效的药物。

Citation： LONG Xiaolan,HUANG Kaisen,XIONG Guojun.. Efficacy and Safety of Magnesium Sulfate Preparations and Macrogol 4000 on New-onset Constipation during Hospitalization among Patients with Coronary Heart Disease. West China Medical Journal, 2013, 28(5): 764-766. doi: 10.7507/1002-0179.20130235 Copy

1.	于普林, 李增金, 郑宏, 等. 老年人便秘流行病学特点的初步分析[J]. 中华老年医学杂志, 2001, 20(2): 132-134.
2.	Chmulson WM, Francisconi C, Olden K, et al. The Latin- American consensus on chronic constipation[J]. Gastroenterol Hepatol, 2008, 31(2): 59-74.
3.	姜明明, 徐杨. 功能性便秘的临床研究进展[J]. 国际病理科学与临床杂志, 2011, 31(2): 155-160.
4.	Ramkumar D, Rao SS. Efficacy and safety of traditional medical therapies for chronic constipation: systematic review[J]. Am J Gastroenterol, 2005, 100(4): 936-71.
5.	Su YJ, Zhang XY, Zeng JS, et al. New-onset constipation at acute stage after first stroke: incidence, risk factors, and impact on the stroke outcome[J]. Strok, 2009, 40(4): 1304-1309.
6.	Salmoirago-Blotcher E, Crawford S, Jackson E, et al. Constipation and risk of cardiovascular disease among postmenopausal women[J]. Am J Med, 2011, 124(8): 714-723.
7.	Salamon JN, Mazurek J, Zolty R. Postmenopausal women with constipation and cardiovascular disease[J]. Am J Med, 2012, 125(2).
8.	Cheng TO. Triggering activities of acute pulmonary embolism and paradoxical embolism[J]. Int J Cardiol, 2006, 109(2): 280-281.
9.	Guerrera MP, Volpe SL, Mao JJ. Therapeutic uses of magnesium[J]. Am Fam Physician, 2009, 80(2): 157-162.
10.	Loening-Baucke V. Prevalence symptoms and outcome of constipation in infants and toddlers[J]. J Pediatr, 2005, 146(3): 359-63.
11.	Chen CC, Su MY, Tung SY, et al. Evaluation of polyethylene glycol plus electrolytes in the treatment of severe constipation and faecal impaction in adults[J]. Curr Med Res Opin, 2005, 21(10): 1595-1602.
12.	罗雪飞, 钟强. 便秘药物的合理选择[J]. 华西医学, 2009, 24(6): 1618-1620.
13.	郑玉霞, 张元, 廖再波. 福松治疗老年慢性功能性便秘的疗效观察及护理指导[J]. 华西医学, 2007, 22(4): 885-886.
14.	陈力挺, 徐瑞华, 周玉甩. 不同方法口服50%硫酸镁行肠道准备效果分析[J]. 安徽医药, 2008, 12(8): 745-746.
15.	张雨晴. 聚乙二醇4000治疗功能性便秘及对生活质量的影响[J]. 安徽卫生职业技术学院学报, 2010(5)：48-49.

1. 　于普林, 李增金, 郑宏, 等. 老年人便秘流行病学特点的初步分析[J]. 中华老年医学杂志, 2001, 20(2): 132-134.
2. 　Chmulson WM, Francisconi C, Olden K, et al. The Latin- American consensus on chronic constipation[J]. Gastroenterol Hepatol, 2008, 31(2): 59-74.
3. 　姜明明, 徐杨. 功能性便秘的临床研究进展[J]. 国际病理科学与临床杂志, 2011, 31(2): 155-160.
4. 　Ramkumar D, Rao SS. Efficacy and safety of traditional medical therapies for chronic constipation: systematic review[J]. Am J Gastroenterol, 2005, 100(4): 936-71.
5. 　Su YJ, Zhang XY, Zeng JS, et al. New-onset constipation at acute stage after first stroke: incidence, risk factors, and impact on the stroke outcome[J]. Strok, 2009, 40(4): 1304-1309.
6. 　Salmoirago-Blotcher E, Crawford S, Jackson E, et al. Constipation and risk of cardiovascular disease among postmenopausal women[J]. Am J Med, 2011, 124(8): 714-723.
7. 　Salamon JN, Mazurek J, Zolty R. Postmenopausal women with constipation and cardiovascular disease[J]. Am J Med, 2012, 125(2).
8. 　Cheng TO. Triggering activities of acute pulmonary embolism and paradoxical embolism[J]. Int J Cardiol, 2006, 109(2): 280-281.
9. 　Guerrera MP, Volpe SL, Mao JJ. Therapeutic uses of magnesium[J]. Am Fam Physician, 2009, 80(2): 157-162.
10. 　Loening-Baucke V. Prevalence symptoms and outcome of constipation in infants and toddlers[J]. J Pediatr, 2005, 146(3): 359-63.
11. 　Chen CC, Su MY, Tung SY, et al. Evaluation of polyethylene glycol plus electrolytes in the treatment of severe constipation and faecal impaction in adults[J]. Curr Med Res Opin, 2005, 21(10): 1595-1602.
12. 　罗雪飞, 钟强. 便秘药物的合理选择[J]. 华西医学, 2009, 24(6): 1618-1620.
13. 　郑玉霞, 张元, 廖再波. 福松治疗老年慢性功能性便秘的疗效观察及护理指导[J]. 华西医学, 2007, 22(4): 885-886.
14. 　陈力挺, 徐瑞华, 周玉甩. 不同方法口服50%硫酸镁行肠道准备效果分析[J]. 安徽医药, 2008, 12(8): 745-746.
15. 　张雨晴. 聚乙二醇4000治疗功能性便秘及对生活质量的影响[J]. 安徽卫生职业技术学院学报, 2010(5)：48-49.

Previous Article
Analysis of the Causes of Child Death under Five Years of Age in Leshan City from 2005 to 2010
Next Article
睾丸畸胎瘤的超声诊断及其鉴别诊断

West China Medical Journal

Efficacy and Safety of Magnesium Sulfate Preparations and Macrogol 4000 on New-onset Constipation during Hospitalization among Patients with Coronary Heart Disease

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content