The Incidence of Hypokalemia Associated with Continuous Ambulatory Peritoneal Dialysis Patients and Its Clinical Significance_West China Medical Journal

Authors：

BO Tianhui ,  GAO Xiu , ZHAO Wei , WANG Jingyan.

Department of Nephrology, Peking University Shougang Hospital, Beijing 100144, P. R. China;

Corresponding author：

GAO Xiu, Email: snbjdxsgyy@163.com

Keywords：

腹膜透析; 低钾血症; 危险因素

DOI：

10.7507/1002-0179.20130265

Video：

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目的　探讨持续性非卧床腹膜透析（CAPD）患者低钾血症的发生及临床特点。方法　选取2002年12月－2011年12月采取持续非卧床腹膜透析治疗的47例尿毒症患者，就其透析过程中低钾血症发生情况进行总结分析。结果　低钾血症31例（66%）；低钾血症组与非低钾血症组比较，低钾血症组血尿素氮、肌酐、血钠、血氯、血钙及白蛋白明显降低（P＜0.05）；两组年龄、性别、糖尿病肾病所占的比例及透析龄差异均无统计学意义（P＞0.05）。血钾水平随白蛋白浓度、血氯及血钙的提高而下降（OR=0.756， 0.772，0.022，P＜0.05）。结论　密切联系、定期随诊观察CAPD患者，提高患者就诊依从性，及时发现与纠正低钾血症，有助于提高CAPD患者的生活质量与长期存活率。

Citation： BO Tianhui,GAO Xiu,ZHAO Wei,WANG Jingyan.. The Incidence of Hypokalemia Associated with Continuous Ambulatory Peritoneal Dialysis Patients and Its Clinical Significance. West China Medical Journal, 2013, 28(6): 844-846. doi: 10.7507/1002-0179.20130265 Copy

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6.	鲁新红, 孙玲华, 汪涛. 应用持续质量改进减少腹膜透析病人低钾血症的发生[J]. 护理研究, 2006, 20(35): 3224-3226.
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1. 　汪涛. 腹膜透析的现状与展望[J]. 中国实用内科杂志, 2006, 26(2): 92-95.
2. 　刘平, 王海燕. 肾脏病学[M]. 2版. 北京: 人民卫生出版社, 1996: 1555.
3. 　Szeto CC, Chow KM, Kwan BC, et al. Hypokalemia in Chinese peritoneal dialysis patients: prevalence and prognostic implication[J]. Am J Kidney Dis, 2005, 46(1): 128-135．.
4. 　董捷, 范敏华, 齐慧敏, 等. 腹膜透析患者营养不良和蛋白质能量摄人不足的临床影响因素分析[J]. 中华医学杂志, 2002, 82(1): 61-65.
5. 　Chuang YW, Shu KH, YU TM, et al. Hypokalemia: an independent risk factor of enterobacteriaceae peritonitis in CAPD patients[J]. Nephrol Dial Transplant, 2009, 24(5): 1603-1608.
6. 　鲁新红, 孙玲华, 汪涛. 应用持续质量改进减少腹膜透析病人低钾血症的发生[J]. 护理研究, 2006, 20(35): 3224-3226.
7. 　中国营养学会.中国居民膳食营养素参考摄入量[J]. 营养学报, 2001, 23(3): 193-196.
8. 　Judith AB,Vinod KB.Medical nutrition therapy in chronic kidney failure:Integrating clinical practice guidelines[J]. J Am Diebetic Assoc, 2004, 104(3): 404-409.
9. 　王树人, 金惠铭, 王建枝. 病理生理学[M]. 6版. 北京:人民卫生出版社, 2004: 34.
10. 　Traut M, Haufe CC, Eismann U, et al. Increased binding of beta-2-microglobulin to blood cells in dialysis patients treated with high-Flux dialyzers compared with low-Flux membranes contributed to reduced beta-2-microglobulin concentrations[J]. Blood Purif, 2007, 25(5-6): 432-440.

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West China Medical Journal

The Incidence of Hypokalemia Associated with Continuous Ambulatory Peritoneal Dialysis Patients and Its Clinical Significance

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