Risk Factors for Carotid Stenosis in Patients with Ischemic Cerebrovascular Disease_West China Medical Journal

Authors：

 GONGSi-yin , ZHOUMu-ke , ZHENGHong-bo , JIANGYi ,  HELi

Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;

Corresponding author：

HELi, Email: heli2003new@126.com

Keywords：

Ischemic cerebrovascular disease; Carotid stenosis; Risk factor; Digital subtraction angiography

DOI：

10.7507/1002-0179.20140064

Video：

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Objective To analysis the risk factors for carotid stenosis in patients with ischemic cerebrovascular disease based on digital subtraction angiography. Methods A total of 312 patients diagnosed with ischemic cerebrovascular disease who underwent digital subtraction angiography from June 2011 to September 2013 were selected.The risk factors of carotid stenosis were analysised by multivariate logistic regression analysis. Results In 312 patients,271 were with cerebral infarction and 41 were transient ischemic attack patients.There were 149 patients in carotid stenosis group (stenosis degree ≥50%) and 163 patients in control group (stenosis degree<50%).The age (OR=1.037,P=0.000) and coronary heart disease (OR=4.121,P=0.001) were independent risk factors of carotid stenosis with ischemic cerebrovascular disease. Conclusion Carotid stenosis is common in ischemic cerebrovascular disease.Age and coronary heart disease were the independent risk factors.The recognition and control of these risk factors are in favor of secondary prevention of ischemic cerebrovascular disease.

Citation： GONGSi-yin, ZHOUMu-ke, ZHENGHong-bo, JIANGYi, HELi. Risk Factors for Carotid Stenosis in Patients with Ischemic Cerebrovascular Disease. West China Medical Journal, 2014, 29(2): 210-213. doi: 10.7507/1002-0179.20140064 Copy

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1. 饶明俐.《中国脑血管病防治指南》摘要(一)[J].中风与神经疾病杂志,2005,22(5):388-393.
2. Zhu CZ,Norris JW.Role of carotid stenosis in ischemic stroke[J].Stroke,1990,21(8):1131-1134.
3. 郑宇,华扬,凌晨,等.颈动脉狭窄的危险因素与缺血性卒中的相关性分析[J].中国超声诊断杂志,2004,5(1):4-6.
4. 华扬,郑宇,凌晨,等.动脉粥样硬化危险因素与颈动脉狭窄和缺血性卒中的相关性[J].中国脑血管病杂志,2004,1(2):69-72.
5. Chang CH,Chang YJ,Lee TH,et al.Risk factors of carotid stenosis in first-ever ischemic stroke in Taiwan:a hospital-based study[J].Acta Neurol Taiwan,2006,15(4):237-243.
6. Dharmasaroja PA,Intharakham K.Risk factors for carotid stenosis in Thai patients with ischemic stroke/TIA[J].Angiology,2010,61(8):789-792.
7. Buskens E,Nederkoorn PJ,Buijs-Van Der Woude T,et al.Imaging of carotid arteries in symptomatic patients:cost-effectiveness of diagnostic strategies[J].Radiology,2004,233(1):101-112.
8. 中华神经科学会.中华神经外科学会.各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380.
9. Madden KP,Karanjia PN,Adams HP,et al.Accuracy of initial stroke subtype diagnosis in the TOAST study.Trial of ORG 10172 in Acute Stroke Treatment[J].Neurology,1995,45(11):1975-1979.
10. North American Symptomatic Carotid Endarterectomy Trial Collaborators.Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis[J].N Engl J Med,1991,325(7):445-453.
11. 周衡,王拥军,王素香,等.急性缺血性脑卒中的TOAST亚型分析[J].中华内科杂志,2004,43(7):495-498.
12. 许晓辉,许予明,谈颂,等.缺血性卒中改良的TOAST分型与OCSP分型关系的研究[J].中国实用内科杂志,2008,28(7):538-539.
13. 王淦楠,王瑶,张晶,等.缺血性脑卒中及其TOAST分型相关危险因素分析[J].江苏医药,2011,37(16):1898-1900.
14. 顾力华,陈斌,魏丹霞,等.急性脑梗死TOAST分型与危险因素的关系[J].实用心脑肺血管病杂志,2013,21(2):51-52.
15. 宋丽,李婉婷,韩杰.缺血性脑卒中TOAST分型及其危险因素、复发分析[J].中国医药科学,2013,3(5):17-19.
16. Gutierrez J,Koch S,Dong C,et al.Racial and ethnic disparities in stroke subtypes:a multiethnic sample of patients with stroke[J/OL].Neurol Sci,(2013-10-15)[2013-12-01].http://www.ncbi.nlm.nih.gov/pubmed/24122024.
17. 黄磊.缺血性脑血管病血管狭窄的评估[D].上海:复旦大学,2008.
18. 侯昊明.缺血性脑血管病患者脑动脉狭窄特点的研究[D].南京:第一军医大学,2006.
19. 丁建平,华扬,凌晨,等.缺血性脑卒中患者动脉粥样硬化分布的临床研究[J].中国现代神经疾病杂志,2006,6(4):266-270.
20. Man BL,Fu YP,Chan YY,et al.Lesion patterns and stroke mechanisms in concurrent atherosclerosis of intracranial and extracranial vessels[J].Stroke,2009,40(10):3211-3215.
21. 中华医学会神经病学分会脑血管病学组缺血性脑血管病血管内介入诊疗指南撰写组.中国缺血性脑血管病血管内介入诊疗指南[J].中华神经科杂志,2011,44(12):863-868.

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Risk Factors for Carotid Stenosis in Patients with Ischemic Cerebrovascular Disease

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