Survey and Analysis on Antibiotic Use from 23 Hospitals in Sichuan Province in 2011_West China Medical Journal

Authors：

HUANGWen-zhi , ZHUANGHong-di , LIShi-yu ,  QIAOFu , WANGYan-tong , YINWei-jia , ZONGZhi-yong , RAOLi

Department of Nosocomial Infection Management, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;

Corresponding author：

QIAOFu, Email: qiaofu2005@gmail.com

Keywords：

Cross-sectional survey; Antimicrobial agents; Rational drug use

DOI：

10.7507/1002-0179.20140123

Video：

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Objective To investigate and analyze the antibiotic use in Sichuan Province. Methods Antibiotic use of inpatients was investigated in 23 hospitals on the day of June 25, 2011. Results The percentage of antibiotic use was 42.4% in the total 27 144 inpatients, the range of which was between 24.3% and 63.3% for each hospital. And 63.8% of the antibiotic use was for therapeutic purpose, and 72.2% used only one antibiotic drug. A total of 36.9% of the patients receiving antibiotic treatment for therapeutic use sent samples for pathogenic detection. With the increase of the size of the hospital (judged by the number of beds), antimicrobial drug utilization decreased with statistical significance (χ²=411.834, P=0.000). With the improvement of regional economic level (judged by per-capita GDP of each region), the hospital antimicrobial usage decreased with statistical significance (χ²=500.093, P=0.000). The three types of antimicrobial drug most frequently used were other β-lactam antibiotics, penicillin and third generation cephalosporin. Conclusion Antibiotic use is reasonable in Sichuan Province as a whole. However, it is necessary to reduce irrational use of antimicrobial agents continuously, and to strengthen the management of clinical antibiotic usage among inpatients.

Citation： HUANGWen-zhi, ZHUANGHong-di, LIShi-yu, QIAOFu, WANGYan-tong, YINWei-jia, ZONGZhi-yong, RAOLi. Survey and Analysis on Antibiotic Use from 23 Hospitals in Sichuan Province in 2011. West China Medical Journal, 2014, 29(3): 404-408. doi: 10.7507/1002-0179.20140123 Copy

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2. 四川省统计局. 四川统计年鉴2012[M]. 北京:中国统计出版社, 2012:44.
3. 中华人民共和国国家卫生和计划生育委员会. 2013年全国抗菌药物临床应用专项整治活动方案[EB/OL]. (2013-05-07)[2013-12-01]. http://www.moh.gov.cn/ewebeditor/uploadfile/2013/05/20130509133856278.doc.
4. 吴安华, 李春辉, 文细毛, 等. 2010年中国740所医院住院患者抗菌药物日使用率调查[J]. 中国感染控制杂志, 2012, 11(1):7-11.
5. 任南, 文细毛, 吴安华. 全国医院感染横断面调查结果的变化趋势研究[J]. 中国感染控制杂志, 2007, 6(1):16-18.
6. 张骥, 王翀, 熊鸿燕, 等. 2010年度贵州省108所医院住院患者横断面抗菌药物使用率调查[J]. 中国感染控制杂志, 2012, 11(6):430-434.
7. 邢红霞, 张红鹰, 张建平, 等. 华北地区18所医院抗菌药物使用管理调查[J]. 中华医院感染学杂志, 2003, 13(9):858-860.
8. 刘敬伟. 长沙市医保住院患者抗菌药物使用的流行病学研究[D]. 长沙:中南大学, 2011.
9. 陈峰英, 王砚, 徐琪. 住院病人抗菌药物使用调查结果分析及管理措施[J]. 中国医药导报, 2007, 4(26):164-165.
10. 孙丽萍. 长春市某三甲医院医院感染现况调查分析[D]. 长春:吉林大学, 2010.
11. 徐潜, 孟贵英, 赵学军, 等. 医院抗菌药物应用调查分析[J]. 中华医院感染学杂志, 2002, 12(12):930-932.
12. 韩佳音. 480例住院患者抗菌药物应用与分析[J]. 中国预防医学杂志, 2004, 5(3):194-197.
13. 陈彩芳, 黄建华, 谭秀燕. 抗菌药物应用现状调查及分析[J]. 中华医院感染学杂志, 2004, 14(6):668-670.
14. Zarb P, Coignard B, Griskeviciene J, et al. The European centre for disease prevention and control (ECDC) pilot point prevalence survey of healthcare-associated infections and antimicrobial use[J]. Euro Surveill, 2012, 17(46):1-16.
15. Health Protection Agency. English national point prevalence survey on healthcare associated infections and antimicrobial use, 2011:preliminary data[EB/OL]. (2012-05-22)[2013-12-01]. http://www.hpa.org.uk/webc/HPAwebFile/HPAweb_C/1317134305239.

West China Medical Journal

Survey and Analysis on Antibiotic Use from 23 Hospitals in Sichuan Province in 2011

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