• Department of Hematology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;
JIAYong-qian, Email: jia_yq@163.com
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Objective To evaluate the diagnostic value of T-SPOT.TB assay in patients with hematological disorders and tuberculosis. Methods A total of 82 patients with hematological disorders and suspected tuberculosis diagnosed between March 2012 and April 2013 received T-SPOT. TB assay in the peripheral blood mononuclear cells. Results The positive detection rate of T-SPOT.TB assay for patients with hematological disorders and tuberculosis was 59.09% (13/22), which was higher than the positive detection rate of anti-TB antibody test[13.64% (3/22)]. The sensibility and specificity of T-SPOT.TB assay for patients with hematological disorders and tuberculosis was 59.09% (13/22) and 68.33% (41/60), respectively. Conclusion T-SPOT.TB assay is of great value on diagnosis of tuberculosis for patients with hematological disorders and suspected tuberculosis. The diagnostic value of T-SPOT.TB assay is more important for tuberculosis infected patients; it can be used as an accessorial diagnostic method for patients with hematological disorder and suspected tuberculosis.

Citation: RENQian, JIAYong-qian, ZENGJi-sha. Diagnostic Value of T-SPOT.TB Assay in Patients with Hematological Disorders and Tuberculosis. West China Medical Journal, 2014, 29(4): 607-609. doi: 10.7507/1002-0179.20140183 Copy

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