Multivariate Survival Analysis of Early Death Prognosis of Acute Myocardial Infarction_West China Medical Journal

Authors：

 WANGJian ¹ , HUHai ² , CHENJin-gang ² ,  TANGShi-yuan ²

1. Department of Emergency, Ziyang First People's Hospital, Ziyang, Sichuan 641300, P. R. China;
2. Department of Emergency, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;

Corresponding author：

TANGShi-yuan, Email: tangshiyuan266@163.com

Keywords：

Acute myocardial infarction; Mortality risk; Age; Isoenzymes of creatine kinase

DOI：

10.7507/1002-0179.20140311

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Objective To evaluate the prognosis factors for early death (within 60 days) of acute myocardial infarction (AMI) patients for early identification and prevention of the disease. Methods We analyzed the information of AML patients who were admitted to the emergency department between May 2009 and July 2010, and analyzed their clinical data, such as gender, age, prehospital time, myocardial enzyme, electrocardiogram, complications, whether the patients had thrombolysis therapy, time of thrombolysis, end point observation and time of death, ect. Cox multivariate survival analysis was performed with the use of SPSS 18.0 software. Results Seventy-one cases were collected with one of them excluded for fragmented data. After analysing, we found that patients' age and isoenzymes of creatine kinase (CK-MB) level were prognosis factors for early death. Further analysis showed that the relative risk (RR) of age was 1.166 (P=0.023), and the RR of CK-MB was 1.001 (P=0.004). Conclusion Patients' age has predictive value for early death of AML. More attention should be paid to AML patients with advanced age. Detecting myocardial enzymes levels, especially the CK-MB level, is significant for predicting early death. Other indicators need to be further explored due to the possible limitation of our study.

Citation： WANGJian, HUHai, CHENJin-gang, TANGShi-yuan. Multivariate Survival Analysis of Early Death Prognosis of Acute Myocardial Infarction. West China Medical Journal, 2014, 29(6): 1019-1021. doi: 10.7507/1002-0179.20140311 Copy

1.	李文文, 马丽萍, 秦永文, 等. 急性心肌梗死患者院内死亡及影响因素的回顾性分析[J]. 第二军医大学学报, 2013, 34(11): 1187-1193.
2.	张先林, 王岳松, 章萍, 等. 急性心肌梗死患者经桡动脉行急诊介入治疗的临床分析[J]. 中华全科医学, 2013, 11(12): 1875-1876.
3.	王淑华. 急性心肌梗塞在急诊室的溶栓救治临床观察[J]. 内蒙古医科大学学报, 2013, 35(S1): 94-95.
4.	高戎, 钱骏, 徐建如. KAMIR评分与GRACE评分预测急性心肌梗死患者一年死亡率的临床研究[J]. 中国急救医学, 2013, 33(2): 140-142.
5.	钟光珍, 那开宪. 全球心肌梗死统一定义指南解读[J]. 中国临床医生, 2009, 37(4): 70-71.
6.	蒲泽晏, 龚国忠, 刘世军, 等. 心肌标志物检测在早期诊断急性心肌梗死中的价值[J]. 国际检验医学杂志, 2014, 35(2): 144-145.
7.	文朝. 心肌坏死标志物联合检测在急性心肌梗死早期诊断及鉴别中的意义[J]. 中国实验诊断学, 2013, 17(11): 2013-2015.
8.	李艳, 于海初, 王其新. 急性冠脉综合征患者NT-proBNP、超敏C反应蛋白及心肌酶学相关研究[J]. 中国循证心血管医学杂志, 2011, 3(1): 50-52.
9.	姚蓝, 谢小铭. 急性心肌梗死院前溶栓治疗的Meta分析[J]. 中华急诊医学杂志, 2010, 19(8): 811-816.
10.	杜宏娟, 孙德国, 赵利华. 老年急性ST段抬高心肌梗死患者静脉溶栓效果[J]. 中国老年学杂志, 2013, 33(24): 6272-6273.
11.	曲俊桥, 房文芝, 马金娥, 等. 基层医院急性心肌梗死不依从溶栓原因分析[J]. 华西医学, 2010, 25(2): 436.
12.	周秀明, 郭莹婧, 闫明洲, 等. ST段抬高心肌梗死转运急诊介入治疗的疗效观察[J]. 吉林医学, 2014, 35(7): 1390-1391.
13.	张新梅, 胡允兆, 陈样新, 等. 急性心肌梗死住院死亡危险因素分析[J]. 广东医学, 2013, 34(2): 260-263.
14.	刘勋. 非胸痛的急性心肌梗死48例临床分析[J]. 华西医学, 2011, 26(12): 1868-1869.
15.	文秀兰, 邹利群, 马建英. 130例急性心肌梗死患者院前急救时间延误分析[J]. 华西医学, 2009, 24(9): 2438-2440.

1. 李文文, 马丽萍, 秦永文, 等. 急性心肌梗死患者院内死亡及影响因素的回顾性分析[J]. 第二军医大学学报, 2013, 34(11): 1187-1193.
2. 张先林, 王岳松, 章萍, 等. 急性心肌梗死患者经桡动脉行急诊介入治疗的临床分析[J]. 中华全科医学, 2013, 11(12): 1875-1876.
3. 王淑华. 急性心肌梗塞在急诊室的溶栓救治临床观察[J]. 内蒙古医科大学学报, 2013, 35(S1): 94-95.
4. 高戎, 钱骏, 徐建如. KAMIR评分与GRACE评分预测急性心肌梗死患者一年死亡率的临床研究[J]. 中国急救医学, 2013, 33(2): 140-142.
5. 钟光珍, 那开宪. 全球心肌梗死统一定义指南解读[J]. 中国临床医生, 2009, 37(4): 70-71.
6. 蒲泽晏, 龚国忠, 刘世军, 等. 心肌标志物检测在早期诊断急性心肌梗死中的价值[J]. 国际检验医学杂志, 2014, 35(2): 144-145.
7. 文朝. 心肌坏死标志物联合检测在急性心肌梗死早期诊断及鉴别中的意义[J]. 中国实验诊断学, 2013, 17(11): 2013-2015.
8. 李艳, 于海初, 王其新. 急性冠脉综合征患者NT-proBNP、超敏C反应蛋白及心肌酶学相关研究[J]. 中国循证心血管医学杂志, 2011, 3(1): 50-52.
9. 姚蓝, 谢小铭. 急性心肌梗死院前溶栓治疗的Meta分析[J]. 中华急诊医学杂志, 2010, 19(8): 811-816.
10. 杜宏娟, 孙德国, 赵利华. 老年急性ST段抬高心肌梗死患者静脉溶栓效果[J]. 中国老年学杂志, 2013, 33(24): 6272-6273.
11. 曲俊桥, 房文芝, 马金娥, 等. 基层医院急性心肌梗死不依从溶栓原因分析[J]. 华西医学, 2010, 25(2): 436.
12. 周秀明, 郭莹婧, 闫明洲, 等. ST段抬高心肌梗死转运急诊介入治疗的疗效观察[J]. 吉林医学, 2014, 35(7): 1390-1391.
13. 张新梅, 胡允兆, 陈样新, 等. 急性心肌梗死住院死亡危险因素分析[J]. 广东医学, 2013, 34(2): 260-263.
14. 刘勋. 非胸痛的急性心肌梗死48例临床分析[J]. 华西医学, 2011, 26(12): 1868-1869.
15. 文秀兰, 邹利群, 马建英. 130例急性心肌梗死患者院前急救时间延误分析[J]. 华西医学, 2009, 24(9): 2438-2440.

West China Medical Journal

Multivariate Survival Analysis of Early Death Prognosis of Acute Myocardial Infarction

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