Prospective Cohort Study on Quality of Life in Patients Undergoing Renal Transplantation or Hemodialysis_West China Medical Journal

Authors：

 HEYue , SHIXiao-ying , WANGChun-mei , WANGYong-zhi , LIRong

The Third General Ward, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;

Corresponding author：

Keywords：

Renal transplantation; Hemodialysis; Quality of life; Prospective

DOI：

10.7507/1002-0179.20140378

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Objective To compare the quality of life in the early stage of treatment in patients who accepted renal transplantation with those who still were undergoing long-term hemodialysis. Methods Patients undergoing long-term hemodialysis in December 2011 and adult patients who planned to accept renal transplantation within 6 months were chosen to be our study subjects. The Medical Outcomes Study 36-item Short Form Health Survey Questionnaire (SF-36) was used for the study. After 6 months of following up, they were assessed with the same questionnaire again. Those hemodialysis patients who accepted renal transplantation within this period were divided into the intervention group. The quality of life between the two groups was compared then. Results A total of 124 end-stage renal failure patients were involved in our study, in which 79 patients successfully accepted renal transplantation (intervention group) and the other 45 patients who still underwent hemodialysis (control group). No other complications were observed during this period. There was no significant difference in life quality between the two groups before treatment (P>0.05). Six months after the treatment, SF-36 total score and each of the 8 dimension scores for the intervention group were all significantly higher than those for the control group (P<0.05). Conclusion Renal transplantation recipients have a totally better life quality than those who depend on hemodialysis.

Citation： HEYue, SHIXiao-ying, WANGChun-mei, WANGYong-zhi, LIRong. Prospective Cohort Study on Quality of Life in Patients Undergoing Renal Transplantation or Hemodialysis. West China Medical Journal, 2014, 29(7): 1229-1233. doi: 10.7507/1002-0179.20140378 Copy

1.	Kalender B, Ozdemir AC, Dervisoglu E, et al. Quality of life in chronic kidney disease:effects of treatment modality, depression, malnutrition and inflammation[J]. Int J Clin Pract, 2007, 61(4):569-576.
2.	Panagopoulou A, Hardalias A, Berati S, et al. Psychosocial issues and quality of life in patients on renal replacement therapy[J]. Saudi J Kidney Dis Transpl, 2009, 20(2):212-218.
3.	陈灏珠, 林果为. 实用内科学[M]. 10版. 北京:人民卫生出版社, 2009:1775.
4.	Olssøn I, Mykletun A, Dahl AA. The hospital anxiety and depression rating scale:a cross-sectional study of psychometrics and case finding abilities in general practice[J]. BMC Psychiatry, 2005, 5(4):46.
5.	张作记. 行为医学量表手册[M]. 北京:中华医学电子音像出版社, 2005:54-59.
6.	邓燕青, 徐涛, 祖丽安, 等. 肾移植后患者生活质量评分专用量表的制订及相关因素分析[J]. 护理学杂志, 2006, 21(24):7-10.
7.	王芳, 何强, 洪大情, 等. 持续静静脉血液滤过和持续低效每日透析治疗重症急性肾损伤的临床研究[J]. 中国血液净化, 2011, 10(6):306-309.
8.	张佩芳, 徐勤芳, 谭晓珍. 亲属活体肾移植供者术后生活质量与社会支持的调查研究[J]. 护理研究, 2010, 24(13):1142-1144.
9.	郭宏波. 肾移植与血液透析患者生活质量对比[J]. 中国组织工程研究与临床康复, 2008, 12(31):6117-6121.
10.	Tavallaii SA, Einollahi B, Azizabadi Farahani M, et al. Socioeconomic links to health-related quality of life, anxiety, and depression in kidney transplant recipients[J]. Iran J Kidney Dis, 2009, 3(1):40-44.
11.	李刚, 马潞林, 黄毅, 等. 不同年龄段活体供肾者的安全性[J]. 北京大学学报·医学版, 2012, 44(4):646-648.
12.	周山, 刘宏, 余荣杰, 等. 肾移植受体93例生存质量调查研究[J]. 第三军医大学学报, 2010, 32(15):1652-1655.
13.	蔡善荣. 健康相关生命质量的研究概况[J]. 国外医学·社会医学分册, 1999, 16(1):4-7.
14.	周英, 尤黎明. 肾移植相关心理问题及其影响因素的研究进展[J]. 中国行为医学科学, 2002, 11(5):595-596.
15.	Frazier PA, Davis-Ali SH, Dahl KE. Correlates of noncompliance among renal transplant recipients[J]. Clin Transplant, 1994, 8(6):550-557.

1. Kalender B, Ozdemir AC, Dervisoglu E, et al. Quality of life in chronic kidney disease:effects of treatment modality, depression, malnutrition and inflammation[J]. Int J Clin Pract, 2007, 61(4):569-576.
2. Panagopoulou A, Hardalias A, Berati S, et al. Psychosocial issues and quality of life in patients on renal replacement therapy[J]. Saudi J Kidney Dis Transpl, 2009, 20(2):212-218.
3. 陈灏珠, 林果为. 实用内科学[M]. 10版. 北京:人民卫生出版社, 2009:1775.
4. Olssøn I, Mykletun A, Dahl AA. The hospital anxiety and depression rating scale:a cross-sectional study of psychometrics and case finding abilities in general practice[J]. BMC Psychiatry, 2005, 5(4):46.
5. 张作记. 行为医学量表手册[M]. 北京:中华医学电子音像出版社, 2005:54-59.
6. 邓燕青, 徐涛, 祖丽安, 等. 肾移植后患者生活质量评分专用量表的制订及相关因素分析[J]. 护理学杂志, 2006, 21(24):7-10.
7. 王芳, 何强, 洪大情, 等. 持续静静脉血液滤过和持续低效每日透析治疗重症急性肾损伤的临床研究[J]. 中国血液净化, 2011, 10(6):306-309.
8. 张佩芳, 徐勤芳, 谭晓珍. 亲属活体肾移植供者术后生活质量与社会支持的调查研究[J]. 护理研究, 2010, 24(13):1142-1144.
9. 郭宏波. 肾移植与血液透析患者生活质量对比[J]. 中国组织工程研究与临床康复, 2008, 12(31):6117-6121.
10. Tavallaii SA, Einollahi B, Azizabadi Farahani M, et al. Socioeconomic links to health-related quality of life, anxiety, and depression in kidney transplant recipients[J]. Iran J Kidney Dis, 2009, 3(1):40-44.
11. 李刚, 马潞林, 黄毅, 等. 不同年龄段活体供肾者的安全性[J]. 北京大学学报·医学版, 2012, 44(4):646-648.
12. 周山, 刘宏, 余荣杰, 等. 肾移植受体93例生存质量调查研究[J]. 第三军医大学学报, 2010, 32(15):1652-1655.
13. 蔡善荣. 健康相关生命质量的研究概况[J]. 国外医学·社会医学分册, 1999, 16(1):4-7.
14. 周英, 尤黎明. 肾移植相关心理问题及其影响因素的研究进展[J]. 中国行为医学科学, 2002, 11(5):595-596.
15. Frazier PA, Davis-Ali SH, Dahl KE. Correlates of noncompliance among renal transplant recipients[J]. Clin Transplant, 1994, 8(6):550-557.

West China Medical Journal

Prospective Cohort Study on Quality of Life in Patients Undergoing Renal Transplantation or Hemodialysis

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