Comparison between the Clinical Outcome of Early and Deferred Intravesical Instillation Therapy in Treating Cystitis Glandularis after Transurethral Resection_West China Medical Journal

Authors：

 LIUJun-feng , TANZhao-hui , LIXing-zhi , CHINing ,  LISan-xiang

Department of Urology, Inner Mongolia People's Hospital, Huhehaote, Inner Mongolia 010017, P. R. China;

Corresponding author：

LISan-xiang, Email: 2294474817@qq.com

Keywords：

Cystitis glandularis; Early intravesical instillation; Effect

DOI：

10.7507/1002-0179.20140561

Video：

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Objective To evaluate the clinical effect of early and deferred intravesical instillation in the treatment of cystitis glandularis after transurethral resection (TUR). Methods We retrospectively analyzed the clinical data of 95 patients with cystitis glandularis during February 2007 to April 2012. Among them, 37 patients underwent the first intravesical instillation within 24 hours after transurethral resection (group A), while the others underwent the same treatment within a week (group B). Then, intravesical instillation in all patients were carried out once every week for 8 weeks, and after that, it was carried out once every month for 5 to 10 months. All the patients were followed up for 12 to 16 months. The cure rate, improvement rate, total effective rate, recurrence rate and incidence of adverse events associated with therapy were observed. Results Recovery rate, improvement rate, side effects were observed in group A and B respectively, and there was no significant difference between the two groups (P>0.05). But there was significant difference in the total effective rate and recurrence rate (P<0.05). Conclusion The first intravesical instillation within 24 hours after transurethral resection in the treatment of cystitis glandularis can improve curative effect and lower recurrence rate, without the increase of side effects.

Citation： LIUJun-feng, TANZhao-hui, LIXing-zhi, CHINing, LISan-xiang. Comparison between the Clinical Outcome of Early and Deferred Intravesical Instillation Therapy in Treating Cystitis Glandularis after Transurethral Resection. West China Medical Journal, 2014, 29(10): 1841-1844. doi: 10.7507/1002-0179.20140561 Copy

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9.	崔飞伦, 孙颖浩, 邱镇, 等. 经尿道等离子电切加丝裂霉素膀胱灌注治疗腺性膀胱炎56例[J]. 医学临床研究, 2005, 22(11):1595-1597.
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11.	应俊. 对腺性膀胱炎治疗的再认识[J]. 中国全科医学, 2008, 11(8):683-684.
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14.	任尚青, 候琳, 邓实, 等. 腺性膀胱炎的诊断与治疗[J]. 四川大学学报·医学版, 2012, 43(6):959-960.
15.	陈月军, 拱华. 经尿道电切电灼术联合吡柔比星膀胱灌注治疗女性腺性膀胱炎48例报告[J]. 临床泌尿外科杂志, 2012, 27(3):222-223.
16.	曾小明, 熊海云, 余明主, 等. 经尿道等离子汽化电切联合术后吡柔比星膀胱灌注治疗腺性膀胱炎[J]. 南昌大学学报·医学版, 2013, 53(7):19-21.
17.	熊林, 余书勇, 邹茜, 等. 经尿道超脉冲等离子体双极电切术联合膀胱灌注化疗治疗腺性膀胱炎44例[J]. 中华腔镜泌尿外科杂志·电子版, 2012, 6(2):39-41.
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19.	宋东奎, 邢东亮. 经尿道汽化术联合吡柔比星膀胱保留灌注治疗腺性膀胱炎[J]. 肿瘤研究与临床, 2005, 17(6):413-414.

1. 姚友生, 林明恩. 腺性膀胱炎诊疗新进展[J]. 广东医学, 2010, 31(1):45-46.
2. Jost SP, Dixon JS, Gosling JA, et al. Ultrastructural observations on cystitis cystica in human bladder urothelium[J]. Br J Urol, 1993, 71(1):2833.
3. 容伟超, 陈国威, 区文贵. 经尿道等离子电切病灶加膀胱灌注吡柔比星预防腺性膀胱炎复发的临床研究[J]. 中国内镜杂志, 2012, 18(3):288-290.
4. 朱建强, 王永传. 腺性膀胱炎的再认识[J]. 医学综述, 2013, 19(3):493-496.
5. 王亚荣, 唐伟, 喻备, 等. 单纯TUR与TUR联合THP膀胱灌注治疗腺性膀胱炎的Meta分析[J]. 重庆医学, 2013, 42(11):1213-1215.
6. 刘哲, 胡茂胜, 黄德波. 腺性膀胱炎治疗方式选择的探讨[J]. 湖南中医药大学学报, 2009, 29(11):72-75.
7. 侯琳, 屈锐, 任尚青, 等. 经尿道电切后化疗药物灌注治疗腺性膀胱炎疗效的系统评价[J]. 中国循证医学杂志, 2012, 12(10):1251-1260.
8. Lee G, Tsiriopoulos I, Yajnik K, et al. Case report:cystitis glandu-laris mimics bladder tumour:a case report and diagnostic character-istics[J]. Int Urol Nephrol, 2005, 37(4):713-715.
9. 崔飞伦, 孙颖浩, 邱镇, 等. 经尿道等离子电切加丝裂霉素膀胱灌注治疗腺性膀胱炎56例[J]. 医学临床研究, 2005, 22(11):1595-1597.
10. 吴水清, 徐冉, 朱煊, 等. 腺性膀胱炎的治疗进展[J]. 中华临床医师杂志·电子版, 2013, 7(18):8379-8381.
11. 应俊. 对腺性膀胱炎治疗的再认识[J]. 中国全科医学, 2008, 11(8):683-684.
12. 邓健. 腺性膀胱炎60例的临床诊治体会[J]. 华西医学, 2010, 25(1):39-40.
13. 龙清志, 刘润明. 腺性膀胱炎灌注治疗有效[J]. 现代泌尿外科杂志, 2012, 17(6):602-603.
14. 任尚青, 候琳, 邓实, 等. 腺性膀胱炎的诊断与治疗[J]. 四川大学学报·医学版, 2012, 43(6):959-960.
15. 陈月军, 拱华. 经尿道电切电灼术联合吡柔比星膀胱灌注治疗女性腺性膀胱炎48例报告[J]. 临床泌尿外科杂志, 2012, 27(3):222-223.
16. 曾小明, 熊海云, 余明主, 等. 经尿道等离子汽化电切联合术后吡柔比星膀胱灌注治疗腺性膀胱炎[J]. 南昌大学学报·医学版, 2013, 53(7):19-21.
17. 熊林, 余书勇, 邹茜, 等. 经尿道超脉冲等离子体双极电切术联合膀胱灌注化疗治疗腺性膀胱炎44例[J]. 中华腔镜泌尿外科杂志·电子版, 2012, 6(2):39-41.
18. 张朝华, 黄研, 彭洪涛, 等. 吡柔比星膀胱灌注治疗腺性膀胱炎46例[J]. 中国药业, 2009, 18(13):77-78.
19. 宋东奎, 邢东亮. 经尿道汽化术联合吡柔比星膀胱保留灌注治疗腺性膀胱炎[J]. 肿瘤研究与临床, 2005, 17(6):413-414.

West China Medical Journal

Comparison between the Clinical Outcome of Early and Deferred Intravesical Instillation Therapy in Treating Cystitis Glandularis after Transurethral Resection

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