改良电休克治疗麻醉用药研究进展_West China Medical Journal

Authors：

 贺银 ,  罗朝志

四川大学华西医院麻醉科（成都，610041）;

Corresponding author：

罗朝志, Email: chaozhil@aliyun.com

Keywords：

改良电休克治疗; 发作持续时间; 麻醉药

DOI：

10.7507/1002-0179.20140600

Video：

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电休克治疗是精神科常用的一种治疗手段，但易导致缺氧等并发症的发生。改良电休克治疗（MECT）技术的引入，为精神病患者提供了新的治疗手段，同时也对麻醉用药提出了新的要求。虽然现有麻醉用药具有一定抗癫痫作用，但降低了MECT发作时间，影响疗效。现对近年来MECT麻醉诱导所需骨骼肌松弛药、麻醉药和辅助用药对MECT治疗影响的研究进展进行介绍和比较，为MECT麻醉用药提供参考。

Citation： 贺银, 罗朝志. 改良电休克治疗麻醉用药研究进展. West China Medical Journal, 2014, 29(10): 1983-1985. doi: 10.7507/1002-0179.20140600 Copy

1.	Squire LR. Memory functions as affected by electroconvulsive therapy[J]. Ann N Y Acad Sci, 1986, 462(1):307-314.
2.	Holmberg AG, Thesleff S. Succinylkolin jodid som muskelavslappande medel via elektroshock behandling[J]. S Nor Med, 1951, 46(1):1567-1570.
3.	Friedman E. Methohexital anesthesia in electrocerebral therapy[J]. Dis Nerv Syst, 1959, 20(5, Part 2):121-124.
4.	American Psychiatric Association, Task Force on Electroconvulsive Therapy. The practice of ECT:recommendations for treatment, training and privileging[J]. Convuls Ther, 1990, 6(2):85-120.
5.	Mokriski BK, Nagle SE, Papuchis GC, et al. Electroconvulsive therapy-induced cardiac arrhythmias during anesthesia with methohexital, thiamylal, or thiopental sodium[J]. J Clin Anesth, 1992, 4(3):208-212.
6.	Mccleave DJ, Blakemore WB. Anaesthesia for electroconvulsive therapy[J]. Anaesth Intensive Care, 1975, 3(3):250-256.
7.	Fredman B, d'etienne J, Smith I, et al. Anesthesia for electroconvulsive therapy:effects of propofol and methohexital on seizure activity and recovery[J]. Anesth Analg, 1994, 79(1):75-79.
8.	Coffey CE, Fochtmann LJ, Greenberg RM, et al. The practice of electroconvulsive therapy:recommendations for treatment, training, and privileging:a task force report of the American Psychiatric Association[M]. 2nd ed. Washington, DC:American Psychiatric Association, 2001:355.
9.	Weiner RD, Rogers HJ, Davidson JR, et al. Effects of stimulus parameters on cognitive side effects[J]. Ann N Y Acad Sci, 1986, 462(1):315-325.
10.	Lisanby SH, Maddox JH, Prudic J, et al. The effects of electroconvulsive therapy on memory of autobiographical and public events[J]. Arch Gen Psychiatry, 2000, 57(6):581-590.
11.	Butterfield NN, Graf P, Macleod BA, et al. Propofol reduces cognitive impairment after electroconvulsive therapy[J]. J ECT, 2004, 20(1):3-9.
12.	Luo J, Min S, Wei K, et al. Propofol protects against impairment of learning-memory and imbalance of hippocampal Glu/GABA induced by electroconvulsive shock in depressed rats[J]. J Anesth, 2011, 25(5):657-665.
13.	Geretsegger C, Rochowanski E, Kartnig C, et al. Propofol and methohexital as anesthetic agents for electroconvulsive therapy (ECT):a comparison of seizure-quality measures and vital signs[J]. J ECT, 1998, 14(1):28-35.
14.	Swaim JC, Mansour M, Wydo SM, et al. A retrospective comparison of anesthetic agents in electroconvulsive therapy[J]. J ECT, 2006, 22(4):243-246.
15.	Rosa MA, Rosa MO, Marcolin MA, et al. Cardiovascular effects of anesthesia in ECT:a randomized, double-blind comparison of etomidate, propofol, and thiopental[J]. J ECT, 2007, 23(1):6-8.
16.	Abdollahi MH, Izadi A, Hajiesmaeili MR, et al. Effect of etomidate versus thiopental on major depressive disorder in electroconvulsive therapy, a randomized double-blind controlled clinical trial[J]. J ECT, 2012, 28(1):10-13.
17.	Krystal AD, Weiner RD, Dean MD, et al. Comparison of seizure duration, ictal EEG, and cognitive effects of ketamine and methohexital anesthesia with ECT[J]. J Neuropsychiatry Clin Neurosci, 2003, 15(1):27-34.
18.	Mcdaniel WW, Sahota AK, Vyas BV, et al. Ketamine appears associated with better word recall than etomidate after a course of 6 electroconvulsive therapies[J]. J ECT, 2006, 22(2):103-106.
19.	Diazgranados N, Ibrahim LA, Brutsche NE, et al. Rapid resolution of suicidal ideation after a single infusion of an N-methyl-D-aspartate antagonist in patients with treatment-resistant major depressive disorder[J]. J Clin Psychiatry, 2010, 71(12):1605-1611.
20.	Ibrahim L, Diazgranados N, Luckenbaugh DA, et al. Rapid decrease in depressive symptoms with an N-methyl-d-aspartate antagonist in ECT-resistant major depression[J]. Prog Neuropsychopharmacol Biol Psychiatry, 2011, 35(4):1155-1159.
21.	Abdallah CG, Fasula M, Kelmendi B, et al. Rapid antidepressant effect of ketamine in the electroconvulsive therapy setting[J]. J ECT, 2012, 28(3):157-161.
22.	Calarge CA, Crowe RR, Gergis SD, et al. The comparative effects of sevoflurane and methohexital for electroconvulsive therapy[J]. J ECT, 2003, 19(4):221-225.
23.	Rasmussen KG, Laurila DR, Brady BM, et al. Anesthesia outcomes in a randomized double-blind trial of sevoflurane and thiopental for induction of general anesthesia in electroconvulsive therapy[J]. J ECT, 2007, 23(4):236-238.
24.	Akcaboy ZN, Akcaboy EY, Yigitbasł B, et al. Effects of remifentanil and alfentanil on seizure duration, stimulus amplitudes and recovery parameters during ECT[J]. Acta Anaesthesiol Scand, 2005, 49(8):1068-1071.
25.	Slover R, Assil K, Giese A, et al. Substitution of alfentanil for Brevital increases seizure duration for electroconvulsive therapy[J]. Anesth Analg, 1993, 76(Supple 2S):S404.
26.	Bailine SH, Petrides G, Doft M, et al. Indications for the use of propofol in electroconvulsive therapy[J]. J ECT, 2003, 19(3):129-132.

1. Squire LR. Memory functions as affected by electroconvulsive therapy[J]. Ann N Y Acad Sci, 1986, 462(1):307-314.
2. Holmberg AG, Thesleff S. Succinylkolin jodid som muskelavslappande medel via elektroshock behandling[J]. S Nor Med, 1951, 46(1):1567-1570.
3. Friedman E. Methohexital anesthesia in electrocerebral therapy[J]. Dis Nerv Syst, 1959, 20(5, Part 2):121-124.
4. American Psychiatric Association, Task Force on Electroconvulsive Therapy. The practice of ECT:recommendations for treatment, training and privileging[J]. Convuls Ther, 1990, 6(2):85-120.
5. Mokriski BK, Nagle SE, Papuchis GC, et al. Electroconvulsive therapy-induced cardiac arrhythmias during anesthesia with methohexital, thiamylal, or thiopental sodium[J]. J Clin Anesth, 1992, 4(3):208-212.
6. Mccleave DJ, Blakemore WB. Anaesthesia for electroconvulsive therapy[J]. Anaesth Intensive Care, 1975, 3(3):250-256.
7. Fredman B, d'etienne J, Smith I, et al. Anesthesia for electroconvulsive therapy:effects of propofol and methohexital on seizure activity and recovery[J]. Anesth Analg, 1994, 79(1):75-79.
8. Coffey CE, Fochtmann LJ, Greenberg RM, et al. The practice of electroconvulsive therapy:recommendations for treatment, training, and privileging:a task force report of the American Psychiatric Association[M]. 2nd ed. Washington, DC:American Psychiatric Association, 2001:355.
9. Weiner RD, Rogers HJ, Davidson JR, et al. Effects of stimulus parameters on cognitive side effects[J]. Ann N Y Acad Sci, 1986, 462(1):315-325.
10. Lisanby SH, Maddox JH, Prudic J, et al. The effects of electroconvulsive therapy on memory of autobiographical and public events[J]. Arch Gen Psychiatry, 2000, 57(6):581-590.
11. Butterfield NN, Graf P, Macleod BA, et al. Propofol reduces cognitive impairment after electroconvulsive therapy[J]. J ECT, 2004, 20(1):3-9.
12. Luo J, Min S, Wei K, et al. Propofol protects against impairment of learning-memory and imbalance of hippocampal Glu/GABA induced by electroconvulsive shock in depressed rats[J]. J Anesth, 2011, 25(5):657-665.
13. Geretsegger C, Rochowanski E, Kartnig C, et al. Propofol and methohexital as anesthetic agents for electroconvulsive therapy (ECT):a comparison of seizure-quality measures and vital signs[J]. J ECT, 1998, 14(1):28-35.
14. Swaim JC, Mansour M, Wydo SM, et al. A retrospective comparison of anesthetic agents in electroconvulsive therapy[J]. J ECT, 2006, 22(4):243-246.
15. Rosa MA, Rosa MO, Marcolin MA, et al. Cardiovascular effects of anesthesia in ECT:a randomized, double-blind comparison of etomidate, propofol, and thiopental[J]. J ECT, 2007, 23(1):6-8.
16. Abdollahi MH, Izadi A, Hajiesmaeili MR, et al. Effect of etomidate versus thiopental on major depressive disorder in electroconvulsive therapy, a randomized double-blind controlled clinical trial[J]. J ECT, 2012, 28(1):10-13.
17. Krystal AD, Weiner RD, Dean MD, et al. Comparison of seizure duration, ictal EEG, and cognitive effects of ketamine and methohexital anesthesia with ECT[J]. J Neuropsychiatry Clin Neurosci, 2003, 15(1):27-34.
18. Mcdaniel WW, Sahota AK, Vyas BV, et al. Ketamine appears associated with better word recall than etomidate after a course of 6 electroconvulsive therapies[J]. J ECT, 2006, 22(2):103-106.
19. Diazgranados N, Ibrahim LA, Brutsche NE, et al. Rapid resolution of suicidal ideation after a single infusion of an N-methyl-D-aspartate antagonist in patients with treatment-resistant major depressive disorder[J]. J Clin Psychiatry, 2010, 71(12):1605-1611.
20. Ibrahim L, Diazgranados N, Luckenbaugh DA, et al. Rapid decrease in depressive symptoms with an N-methyl-d-aspartate antagonist in ECT-resistant major depression[J]. Prog Neuropsychopharmacol Biol Psychiatry, 2011, 35(4):1155-1159.
21. Abdallah CG, Fasula M, Kelmendi B, et al. Rapid antidepressant effect of ketamine in the electroconvulsive therapy setting[J]. J ECT, 2012, 28(3):157-161.
22. Calarge CA, Crowe RR, Gergis SD, et al. The comparative effects of sevoflurane and methohexital for electroconvulsive therapy[J]. J ECT, 2003, 19(4):221-225.
23. Rasmussen KG, Laurila DR, Brady BM, et al. Anesthesia outcomes in a randomized double-blind trial of sevoflurane and thiopental for induction of general anesthesia in electroconvulsive therapy[J]. J ECT, 2007, 23(4):236-238.
24. Akcaboy ZN, Akcaboy EY, Yigitbasł B, et al. Effects of remifentanil and alfentanil on seizure duration, stimulus amplitudes and recovery parameters during ECT[J]. Acta Anaesthesiol Scand, 2005, 49(8):1068-1071.
25. Slover R, Assil K, Giese A, et al. Substitution of alfentanil for Brevital increases seizure duration for electroconvulsive therapy[J]. Anesth Analg, 1993, 76(Supple 2S):S404.
26. Bailine SH, Petrides G, Doft M, et al. Indications for the use of propofol in electroconvulsive therapy[J]. J ECT, 2003, 19(3):129-132.

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