LIShui-ying , ZHOUQian , ZHANGXiu-ying , WANGQiang , SHENWen-wu
  • Mental Health Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;
SHENWen-wu, Email: wenwu_shen@163.com
Nosocomial infection; Schizophrenia; Risk factors
10.7507/1002-0179.20140624
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Objective To investigate the incidence of nosocomial infection in acute and serious schizophrenic inpatients and its risk factors. Methods Between January 1st and December 31st, 2012, we investigated 1 621 schizophrenic patients on the status of nosocomial infections according to the hospital standard of nosocomial infection diagnosis. They were divided into infected group and uninfected group according to the survey results. The risk factors were analyzed by logistic regression method. Results Twenty-nine infected patients were found among the 1 621 patients, and the incidence rate was 1.79%. Among the nosocomial infections, the most common one was respiratory infection (79.31%), followed by gastrointestinal infection and urinary infection (6.90%). There were significant differences between the two groups of patients in age, hospital stay, positive and negative syndrome scale (PASS), combined somatopathy, the time of protective constraint, modified electraconvulsive therapy (MECT), using two or more antipsychotics drugs, using antibiotics and side effects of drugs (P<0.05). However, there were no statistical differences in gender, age classes, the course of disease, frequency of hospitalization and seasonal incidence of hospital infection (P>0.05). The results of multivariate analysis showed that hospital stay, positive symptom score, negative symptom score, the time of protective constraint, MECT, using two or more antipsychotics drugs and side effects of drugs were the main risk factors for nosocomial infection of inpatients with psychopathy (P<0.05). Conclusion Based on the different traits and treatments of acute and serious schizophrenia, a screening table of infections should be set. For the high risk group of nosocomial infection, effective measures should be taken to prevent and control the nosocomial infection of patients with schizophrenia.

Citation： LIShui-ying, ZHOUQian, ZHANGXiu-ying, WANGQiang, SHENWen-wu. Investigation and Analysis on the Nosocomial Infection in 1 621 Hospitalized Patients with Acute and Serious Schizophrenia. West China Medical Journal, 2014, 29(11): 2073-2076. doi: 10.7507/1002-0179.20140624 Copy

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