Preoperative Application of Budesonide Aerosol Inhalation in the Reduction of Respiratory Adverse Events during Pediatric Anesthesia Recovery_West China Medical Journal

Authors：

 YANGYong , JINZhao-qin , YAOMeng-ran

Department of Anesthesiology, the First People's Hospital of Neijiang City, Neijiang, Sichuan 641000, P. R. China;

Corresponding author：

Keywords：

Budesonide; General anesthesia; Child; Laryngeal mask; Aerosol inhalation; Laryngeal spasm

DOI：

10.7507/1002-0179.20150253

Video：

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Objective To explore the influence of general anesthesia with laryngeal mask and preoperative inhalation of budesonide aerosol on the incidence of respiratory adverse events during pediatric anesthesia recovery. Methods A total of 100 child patients scheduled to undergoing inguinal hernia repair between December 2012 and February 2014 were randomly divided into two groups (group A and B) with 50 in each. All the patients underwent general anesthesia with laryngeal mask, while patients in group B inhaled budesonide aerosol before anesthesia. Then, we observed the incidence of adverse events in both groups, including laryngospasm, respiratory tract infection, and pulmonary complications. Results Compared with group A, patients in group B had a lower incidence of adverse events (P<0.05). Conclusion Preoperative application of budesonide aerosol inhalation can significantly reduce adverse events in the process of anesthesia recovery in children.

Citation： YANGYong, JINZhao-qin, YAOMeng-ran. Preoperative Application of Budesonide Aerosol Inhalation in the Reduction of Respiratory Adverse Events during Pediatric Anesthesia Recovery. West China Medical Journal, 2015, 30(5): 881-884. doi: 10.7507/1002-0179.20150253 Copy

1.	Neuhaus D, Schmitz A, Gerber A, et al. Controlled rapid sequence induction and intubation:an analysis of 1001 children[J]. Paediatr Anaesth, 2013, 23(8):734-740.
2.	Xue FS, Liao X, Li CW, et al. Clinical experience of airway management and tracheal intubation under general anesthesia in patients with scar contracture of the neck[J]. Chin Med J, 2008, 121(11):989-997.
3.	Lahiff C, Kane S, Moss AC. Drug development in inflammatory bowel disease:the role of the FDA[J]. Inflamm Bowel Dis, 2011, 17(12):2585-2593.
4.	Atkinson RW, Kang S, Anderson HR, et al. Epidemiological time series studies of PM2.5 and daily mortality and hospital admissions:a systematic review and meta-analysis[J]. Thorax, 2014, 69(7):660-665.
5.	Yang W, Zhao WJ, Gong ZN, et al. Spatial distribution of inhalable particulate and association with respiratory disease in Beijing City[J]. Huan Jing Ke Xue, 2013, 34(1):237-243.
6.	Abramson M, Voigt T. Ambient air pollution and respiratory disease[J]. Med J Aust, 1991, 154(8):543-553.
7.	Schwartz J. Air pollution and hospital admissions for respiratory disease[J]. Epidemiology, 1996, 7(1):20-28.
8.	Orestes MI, Lander L, Verghese S, et al. Incidence of laryngospasm and bronchospasm in pediatric adenotonsillectomy[J]. Laryngoscope, 2012, 122(2):425-428.
9.	Von Ungern-Sternberg BS, Habre W, Erb TO, et al. Salbutamol premedication in children with a recent respiratory tract infection[J]. Paediatr Anaesth, 2009, 19(11):1064-1069.
10.	Al-Alami AA, Zestos MM, Baraka AS. Pediatric laryngospasm:prevention and treatment[J]. Curr Opin Anaesthesiol, 2009, 22(3):388-395.
11.	Sancini G, Farina F, Battaglia C, et al. Health risk assessment for air pollutants:alterations in lung and cardiac gene expression in mice exposed to Milano winter fine particulate matter (PM2.5)[J]. PLoS One, 2014, 9(10):e109685.
12.	Zhao C, Liao J, Chu W, et al. Involvement of TLR2 and TLR4 and Th1/Th2 shift in inflammatory responses induced by fine ambient particulate matter in mice[J]. Inhal Toxicol, 2012, 24(13):918-927.
13.	Peng A, Dodson KM, Thacker LR, et al. Use of laryngeal mask airway in pediatric adenotonsillectomy[J]. Arch Otolaryngol Head Neck Surg, 2011, 137(1):42-46.
14.	Sierpina DI, Chaudhary H, Walner DL, et al. Laryngeal mask airway versus endotracheal tube in pediatric adenotonsillectomy[J]. Laryngoscope, 2012, 122(2):429-435.
15.	Shetty N, Sharma M, Goneppanavar U, et al. Laryngeal injuries and tracheal intubating conditions with or without muscle relaxation I[J]. Can J Anaesth, 2009, 56(3):261; author reply 262-263.
16.	Jaensson M, Olowsson LL, Nilsson U. Endotracheal tube size and sore throat following surgery:a randomized-controlled study[J]. Acta Anaesthesiol Scand, 2010, 54(2):147-153.
17.	李燕舞, 徐治波, 包勇, 等. 雾化吸入布地奈德治疗重度慢性阻塞性肺疾病急性加重中的作用[J]. 华西医学, 2008, 23(3):519-520.

1. Neuhaus D, Schmitz A, Gerber A, et al. Controlled rapid sequence induction and intubation:an analysis of 1001 children[J]. Paediatr Anaesth, 2013, 23(8):734-740.
2. Xue FS, Liao X, Li CW, et al. Clinical experience of airway management and tracheal intubation under general anesthesia in patients with scar contracture of the neck[J]. Chin Med J, 2008, 121(11):989-997.
3. Lahiff C, Kane S, Moss AC. Drug development in inflammatory bowel disease:the role of the FDA[J]. Inflamm Bowel Dis, 2011, 17(12):2585-2593.
4. Atkinson RW, Kang S, Anderson HR, et al. Epidemiological time series studies of PM2.5 and daily mortality and hospital admissions:a systematic review and meta-analysis[J]. Thorax, 2014, 69(7):660-665.
5. Yang W, Zhao WJ, Gong ZN, et al. Spatial distribution of inhalable particulate and association with respiratory disease in Beijing City[J]. Huan Jing Ke Xue, 2013, 34(1):237-243.
6. Abramson M, Voigt T. Ambient air pollution and respiratory disease[J]. Med J Aust, 1991, 154(8):543-553.
7. Schwartz J. Air pollution and hospital admissions for respiratory disease[J]. Epidemiology, 1996, 7(1):20-28.
8. Orestes MI, Lander L, Verghese S, et al. Incidence of laryngospasm and bronchospasm in pediatric adenotonsillectomy[J]. Laryngoscope, 2012, 122(2):425-428.
9. Von Ungern-Sternberg BS, Habre W, Erb TO, et al. Salbutamol premedication in children with a recent respiratory tract infection[J]. Paediatr Anaesth, 2009, 19(11):1064-1069.
10. Al-Alami AA, Zestos MM, Baraka AS. Pediatric laryngospasm:prevention and treatment[J]. Curr Opin Anaesthesiol, 2009, 22(3):388-395.
11. Sancini G, Farina F, Battaglia C, et al. Health risk assessment for air pollutants:alterations in lung and cardiac gene expression in mice exposed to Milano winter fine particulate matter (PM2.5)[J]. PLoS One, 2014, 9(10):e109685.
12. Zhao C, Liao J, Chu W, et al. Involvement of TLR2 and TLR4 and Th1/Th2 shift in inflammatory responses induced by fine ambient particulate matter in mice[J]. Inhal Toxicol, 2012, 24(13):918-927.
13. Peng A, Dodson KM, Thacker LR, et al. Use of laryngeal mask airway in pediatric adenotonsillectomy[J]. Arch Otolaryngol Head Neck Surg, 2011, 137(1):42-46.
14. Sierpina DI, Chaudhary H, Walner DL, et al. Laryngeal mask airway versus endotracheal tube in pediatric adenotonsillectomy[J]. Laryngoscope, 2012, 122(2):429-435.
15. Shetty N, Sharma M, Goneppanavar U, et al. Laryngeal injuries and tracheal intubating conditions with or without muscle relaxation I[J]. Can J Anaesth, 2009, 56(3):261; author reply 262-263.
16. Jaensson M, Olowsson LL, Nilsson U. Endotracheal tube size and sore throat following surgery:a randomized-controlled study[J]. Acta Anaesthesiol Scand, 2010, 54(2):147-153.
17. 李燕舞, 徐治波, 包勇, 等. 雾化吸入布地奈德治疗重度慢性阻塞性肺疾病急性加重中的作用[J]. 华西医学, 2008, 23(3):519-520.

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Preoperative Application of Budesonide Aerosol Inhalation in the Reduction of Respiratory Adverse Events during Pediatric Anesthesia Recovery

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