Analysis of Related Factors Influencing the Early Survival Time of Patients Undergoing Return of Spontaneous Circulation after Cardio-pulmonary Resuscitation_West China Medical Journal

Authors：

 JIANGPeng , HUHai , HEYa-rong ,  CAOYu

Emergency Department, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;

Corresponding author：

CAOYu, Email: yuyuer@126.com

Keywords：

Return of spontaneous circulation; Cox regression analysis; Survival time; Prognosis

DOI：

10.7507/1002-0179.20150295

Video：

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Objective To find out the possible factors that may affect the survival time of patients undergoing return of spontaneous circulation (ROSC) within seven days of cardio-pulmonary resuscitation. Method We retrospectively collected 20 clinical indicators from 51 patients who underwent ROSC after cardio-pulmonary resuscitation in Emergency Department between August 2013 and February 2015. The indicators included gender, age, duration of cardio-pulmonary resuscitation, blood pressure acquired immediately after ROSC, heart rate, respiration, lactic acid, creatinine, prothrombin time, bilirubin, pH, arterial partial pressure of carbon dioxide, potassium, sodium, blood glucose, atrial natriuretic peptides, leukocyte, platelets, and hemoglobin. Then we analyzed the correlation of these indicators with survival time through Cox regression model. Results The results showed that duration of cardiopulmonary resuscitation[RR=1.053, 95% CI (1.020, 1.088), P=0.002] and systolic blood pressure acquired immediately after ROSC[RR=0.991, 95% CI (0.982, 0.999), P=0.038] significantly affected the survival time of patients after ROSC. Conclusions Duration of cardiopulmonary resuscitation and systolic blood pressure acquired immediately after ROSC may be useful in predicting the survival time of patients after ROSC.

Citation： JIANGPeng, HUHai, HEYa-rong, CAOYu. Analysis of Related Factors Influencing the Early Survival Time of Patients Undergoing Return of Spontaneous Circulation after Cardio-pulmonary Resuscitation. West China Medical Journal, 2015, 30(6): 1027-1030. doi: 10.7507/1002-0179.20150295 Copy

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1. ECC Committee, Subcommittees and Task Forces of the American Heart Association. 2005 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care[J].Circulation, 2005, 112(124):IV1-IV 203.
2. Field JM, Hazinski MF, Sayre MR, et al. 2010 American heart association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care[J]. Circulation, 2010, 122(Suppl 3):S640-S656.
3. 胡海, 杜鑫淼, 张建成, 等. 心肺复苏后自主循环恢复患者死亡风险预测及回归模型建立[J]. 华西医学, 2009, 24(9):2275-2277.
4. 袁伟安. 68例心肺复苏成败原因及对策分析[J]. 中外医学研究, 2014, 12(8):125-126.
5. Neumar RW, Nolan JP, Adrie C, et al. Post-cardiac arrest syndrome:epidemiology, pathophysiology, treatment, and prognostication. A consensus statement from the International Liaison Committee on Resuscitation (American Heart Association, Australian and New Zealand Council on Resuscitation, European Resuscitation Council, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Asia, and the Resuscitation Council of Southern Africa); the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; and the Stroke Council[J]. CiRculation, 2008, 118(23):2452-2483.
6. 王泽惠, 王永进, 侯云生, 等. 心肺复苏后多器官功能障碍综合征临床分析[J]. 中国急救医学, 2005, 28(8):609-610.
7. 沈洪, 王士雯. 2003:中国心肺复苏的关注问题[J]. 中国危重病急救医学, 2003, 15(5):262-264.
8. Saghafinia M, Motamedi MH, Piryaie M, et al. Survival after in-hospital cardiopulmonary resuscitation in a major referral center[J]. Saudi J Anaesth, 2010, 4(2):68-71.
9. 张孝钦, 王兴祥, 丁晨彦, 等. 心搏骤停心肺复苏中若干问题的探讨[J]. 中国全科医学, 2006, 9(10):828-829.
10. 董扬. 心肺复苏自主循环恢复患者预后相关因素分析[J]. 中国医师进修杂志杂志, 2011, 34(18):55-56.
11. 丁旻珺, 谢娟. 心肺复苏自主循环恢复患者预后相关因素分析[J]. 实用医学杂志, 2012, 28(23):3956-3959.
12. Adrie C, Adib-Conquy M, Laurent I, et al. Successful cardiopulmonary resuscitation after cardiac arrest as a "sepsis-like" syndrome[J]. Circulation, 2002, 106(5):562-568.
13. Thompson RJ, Mccullough PA, Kahn JK, et al. Prediction of death and neurologic outcome in the emergency department in out-of-hospital cardiac arrest survivors[J]. Am J Cardiol, 1998, 81(1):17-21.
14. 曾琦, 李诗阳, 谭世峰, 等. 心肺复苏预后因素分析及对策[J]. 中国热带医学, 2006, 6(4):659-660.
15. Laurent I, Monchi M, Chiche JD, et al. Reversible myocardial dysfunction in survivors of out-of-hospital cardiac arrest[J]. J Am Coll Cardiol, 2002, 40(12):2110-2116.
16. Van Den Berghe G, Wilmer A, Hermans G, et al. Intensive insulin therapy in the medical ICU[J]. N Engl J Med, 2006, 354(5):449-461.
17. 冯欣蘅, 崔华中, 韩溟, 等. 影响心肺复苏后存活率的相关因素探讨[J]. 实用医学杂志, 2005, 21(17):1933-1934.
18. 梁实, 张文武, 韩冥, 等. 影响心肺复苏存活率的相关因素探讨[J]. 实用医学杂志, 2005, 21(17):1934.

West China Medical Journal

Analysis of Related Factors Influencing the Early Survival Time of Patients Undergoing Return of Spontaneous Circulation after Cardio-pulmonary Resuscitation

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