创伤后血糖水平对急性伤口感染的影响分析_West China Medical Journal

Authors：

 吕娟 ¹ , 陈佳丽 ² , 李佩芳 ³ ,  宁宁 ²

1. ;
2. ;
3. ;

Corresponding author：

宁宁, Email: gkningning@126.com

Keywords：

血糖水平; 创伤; 伤口感染

DOI：

10.7507/1002-0179.20150525

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目的了解创伤后血糖水平对于急性伤口感染的影响。方法采用横断面调查研究，通过方便抽样的方法选择2012年7月-10月入住骨科的患者进行调查分析。纳入标准为年龄≥ 18周岁，住院时间≥ 3 d，入院时已有急性伤口存在或入院后进行手术治疗的患者。共576例患者纳入研究。结果 576例患者中73例发生伤口感染，发生率为12.7%，其中19例患者的伤口感染属于手术切口感染，发生率为3.3%。研究对象受伤后首次测量的血糖值为3.24～22.30 mmol/L，中位血糖值5.68 mmol/L。伤口发生感染的患者中位血糖值为6.36 mmol/L，而伤口未感染者中位血糖值为5.67 mmol/L，差异有统计学意义（P＜0.001），多因素分析显示血糖水平是伤口感染的独立危险因素（OR=1.592， P＜0.001）。结论创伤后高血糖水平是导致伤口感染的危险因素。

Citation： 吕娟, 陈佳丽, 李佩芳, 宁宁. 创伤后血糖水平对急性伤口感染的影响分析. West China Medical Journal, 2015, 30(10): 1826-1828. doi: 10.7507/1002-0179.20150525 Copy

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1. Singh A, Halder S, Menon GR, et al. Meta-analysis of randomized controlled trials on hydrocolloid occlusive dressing versus conventional gauze dressing in the healing of chronic wounds[J]. Asian J Surg, 2004, 27(1):326-332.
2. Jones J. Examining the multifactorial nature of wound infection[J]. Wound Essentials, 2012, 2(1):90-97.
3. Laird AM, Miller PR, Kilgo PD, et al. Relationship of early hyperglycemia in trauma patients[J]. J Trauma, 2004, 56(5): 1058-1062.
4. Meyfroidt G, Ingels C, Van Den Berghe G. Glycemic control in the ICU[J]. N Engl J Med, 2011, 364(13):1280.
5. Jeremitsky E, Omert L, Dunham CM, et al. Harbingers of poor outcome the day afer severe brain injury:hypothermia, hypoxia, and hypoperfusion[J]. J Trauma, 2003, 54(2):312-319.
6. Kim BO, Kim SW, Lee SM, et al. Relationship of glucose control and wound infection in diabetics after lumbar spine surgery[J]. J Korean Neurosurg Soc, 2005, 37(1):44-47.
7. Lee JH, Kim JJ, Kim YH, et al. Increased risk of peristomal wound infection after percutaneous endoscopic gastrostomy in patients with diabetes mellitus[J]. Dig Liver Dis, 2002, 34(1):857-861.
8. Jeong Y, Mun SP, Chang JH, et al. The risk factors associated with surgical site infection after an abdominal operation[J]. J Korean Surg Soc, 2008, 75(1):177-183.
9. Park JM, Jin SH, Lee SR, et al. Complications with laparoscopically assisted gastrectomy:multivariate analysis of 300 consecutive cases[J]. Surg Endosc, 2008, 22(10):2133-2139.
10. Scalea TM, Bochicchio GV, Bochicchio KM, et al. Tight glycemic control in critically injured trauma patients[J]. Ann Surg, 2007, 246(4):605-612.
11. James E. Blood glucose control in the trauma patient[J]. J Diabetes Sci Technol, 2009, 3(6):1373-1376.

West China Medical Journal

创伤后血糖水平对急性伤口感染的影响分析

Abstract Full text Figures/Tables Video References Cited by

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