Forensic Analysis on Cases of Infant Death after Vaccination_West China Medical Journal

Authors：

 ZHUHai-biao ¹ , LIUYuan ¹ , ZHUPeng ² , YANGYu ¹ , CHENXia-meng ¹ ,  GUANPeng ¹

1. Department of Forensic Pathology, West China School of Preclinical and Forensic Science, Sichuan University, Chengdu, Sichuan 610041, P. R. China;
2. Technology Department of the People's Procuratorate, Chengdu, Sichuan 610041, P. R. China;

Corresponding author：

GUANPeng, Email: guanpengcn@yahoo.com

Keywords：

Infant; Suspected adverse events following immunization; Forensic autopsy; Cause of death; Coupling disease

DOI：

10.7507/1002-0179.20150548

Video：

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Objective To explore the common causes and the clinical pathological characteristics of infant death which occurred after vaccination. Methods The study retrospectively analyzed the data of 13 cases of infant death occurring after vaccination from January 2009 to September 2014 in West China Medico-legal Expertise Center. Results Among the 13 cases of infant death, 12 were dead from lethal respiratory system and cardiovascular system diseases, 1 from mechanic asphyxia caused by milk intake. All cases were coupling disease death and had no direct correlation with vaccination. Conclusion Systematic and comprehensive forensic pathological examination is helpful to clarify the cause of death, reveal the relationship between vaccination and the cause of death, and contribute to proper processing of such incidents.

Citation： ZHUHai-biao, LIUYuan, ZHUPeng, YANGYu, CHENXia-meng, GUANPeng. Forensic Analysis on Cases of Infant Death after Vaccination. West China Medical Journal, 2015, 30(10): 1919-1923. doi: 10.7507/1002-0179.20150548 Copy

1.	王富珍, 崔富强, 刘大卫, 等. 接种乙型肝炎疫苗后10例婴儿死亡的疑似预防接种异常反应分析[J]. 中国疫苗和免疫, 2009, 15(1): 52-57.
2.	张敏. 新生儿家长计划免疫的知晓率及需求调查分析[J]. 中外医学研究, 2012, 10(14):55-56.
3.	许贤芳, 龚培玉. 注射乙脑疫苗过敏反应一例[J]. 解剖与临床, 1997, 2(4):191.
4.	张延炀, 路明霞, 王燕, 等. 1993~2013年疫苗接种不良反应的文献分析[J]. 中国生物制品学杂志, 2014, 27(4):548-549.
5.	王长双, 路明霞, 张肖肖, 等. 河南省2010-2011年疑似预防接种异常反应死亡病例分析[J]. 当代医学, 2014, 20(7):162-164.
6.	Zhou W, Pool V, Iskander JK, et al. Surveillance for safety after immunization:Vaccine Adverse Event Reporting System (VAERS)—— United States, 1991-2001[J]. MMWR Surveill Summ, 2003, 52(1):1-24.
7.	常利民, 刘大卫, 李克莉, 等. 全国2008~2010年接种疫苗后过敏性休克监测结果分析[J]. 中国疫苗和免疫, 2012, 18(5):398-401, 446.
8.	Silvers LE, Ellenberg SS, Wise RP, et al. The epidemiology of fatalities reported to the vaccine adverse event reporting system 1990-1997[J]. Pharmacoepidemiol Drug Saf, 2001, 10(4):279-285.
9.	Kim JH, Cho HY, Hennessey KA, et al. Adverse events following immunization (AEFI) with the novel influenza A (H₁N₁) 2009 vaccine: ndings from the National registry of all vaccine recipients and AEFI and the passive surveillance system in South Korea[J]. Jpn J Infect Dis, 2012, 65(2):99-104.
10.	胡家瑜, 黄卓英, 陶黎纳, 等. 上海市2006~2008年预防接种后死亡病例分析[J]. 中国疫苗和免疫, 2010, 16(2):165-168.
11.	李欣影, 宋凤卿, 练巧玲, 等. 532例5岁以下住院儿童主要死因分析[J]. 北华大学学报:自然科学版, 2008, 9(4):350-352.
12.	吴兴龙, 黄佳佳, 谭娜, 等. 婴幼儿58例死亡原因尸检病理和医疗纠纷原因分析[J]. 中华实用儿科临床杂志, 2014, 29(6):431-435.
13.	华秀凤. 41例新生儿死亡分析与对策[J]. 青海医药杂志, 2001, 31(1):39-40.
14.	李克莉, 武文娣, 刘大卫, 等. 猝死与流行性感冒疫苗接种后死亡综述[J]. 中国疫苗和免疫, 2010, 16(3):270-273.
15.	杜彦克. 同时接种百白破联合疫苗和脊髓灰质炎疫苗后偶合窒息死亡1例[J]. 中国计划免疫, 2007, 13(4):297.
16.	蒋纯艳, 谢和清, 陈娟, 等. 1310例甲型H₁N₁流感裂解疫苗接种的安全性观察及干预措施[J]. 中国现代医学杂志, 2010, 20(23): 3598-3602.
17.	方义湖, 张可丽, 于海胜, 等. 202例医疗纠纷的病理尸检的回顾分析[J]. 浙江大学学报:医学版, 2013, 42(4):456-460.

1. 王富珍, 崔富强, 刘大卫, 等. 接种乙型肝炎疫苗后10例婴儿死亡的疑似预防接种异常反应分析[J]. 中国疫苗和免疫, 2009, 15(1): 52-57.
2. 张敏. 新生儿家长计划免疫的知晓率及需求调查分析[J]. 中外医学研究, 2012, 10(14):55-56.
3. 许贤芳, 龚培玉. 注射乙脑疫苗过敏反应一例[J]. 解剖与临床, 1997, 2(4):191.
4. 张延炀, 路明霞, 王燕, 等. 1993~2013年疫苗接种不良反应的文献分析[J]. 中国生物制品学杂志, 2014, 27(4):548-549.
5. 王长双, 路明霞, 张肖肖, 等. 河南省2010-2011年疑似预防接种异常反应死亡病例分析[J]. 当代医学, 2014, 20(7):162-164.
6. Zhou W, Pool V, Iskander JK, et al. Surveillance for safety after immunization:Vaccine Adverse Event Reporting System (VAERS)—— United States, 1991-2001[J]. MMWR Surveill Summ, 2003, 52(1):1-24.
7. 常利民, 刘大卫, 李克莉, 等. 全国2008~2010年接种疫苗后过敏性休克监测结果分析[J]. 中国疫苗和免疫, 2012, 18(5):398-401, 446.
8. Silvers LE, Ellenberg SS, Wise RP, et al. The epidemiology of fatalities reported to the vaccine adverse event reporting system 1990-1997[J]. Pharmacoepidemiol Drug Saf, 2001, 10(4):279-285.
9. Kim JH, Cho HY, Hennessey KA, et al. Adverse events following immunization (AEFI) with the novel influenza A (H₁N₁) 2009 vaccine: ndings from the National registry of all vaccine recipients and AEFI and the passive surveillance system in South Korea[J]. Jpn J Infect Dis, 2012, 65(2):99-104.
10. 胡家瑜, 黄卓英, 陶黎纳, 等. 上海市2006~2008年预防接种后死亡病例分析[J]. 中国疫苗和免疫, 2010, 16(2):165-168.
11. 李欣影, 宋凤卿, 练巧玲, 等. 532例5岁以下住院儿童主要死因分析[J]. 北华大学学报:自然科学版, 2008, 9(4):350-352.
12. 吴兴龙, 黄佳佳, 谭娜, 等. 婴幼儿58例死亡原因尸检病理和医疗纠纷原因分析[J]. 中华实用儿科临床杂志, 2014, 29(6):431-435.
13. 华秀凤. 41例新生儿死亡分析与对策[J]. 青海医药杂志, 2001, 31(1):39-40.
14. 李克莉, 武文娣, 刘大卫, 等. 猝死与流行性感冒疫苗接种后死亡综述[J]. 中国疫苗和免疫, 2010, 16(3):270-273.
15. 杜彦克. 同时接种百白破联合疫苗和脊髓灰质炎疫苗后偶合窒息死亡1例[J]. 中国计划免疫, 2007, 13(4):297.
16. 蒋纯艳, 谢和清, 陈娟, 等. 1310例甲型H₁N₁流感裂解疫苗接种的安全性观察及干预措施[J]. 中国现代医学杂志, 2010, 20(23): 3598-3602.
17. 方义湖, 张可丽, 于海胜, 等. 202例医疗纠纷的病理尸检的回顾分析[J]. 浙江大学学报:医学版, 2013, 42(4):456-460.

West China Medical Journal

Forensic Analysis on Cases of Infant Death after Vaccination

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