前列腺软斑症病例报道和文献复习_West China Medical Journal

Authors：

 翁欣 , 陈铌 , 龚静 , 陈雪芹 , 聂玲 ,  周桥

四川大学华西医院病理科成都 610041;

Corresponding author：

周桥, Email: zhou_qiao@hotmail.com

Keywords：

前列腺; Michaelis-Gutmann小体; 软斑症

DOI：

10.7507/1002-0179.20150600

Video：

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目的探讨前列腺软斑症的临床病理特征、诊断与鉴别诊断。方法分析2012年7月17日就诊的1例前列腺软斑症的临床表现及病理学特征，并复习相关文献。结果患者为老年男性，血清前列腺特异抗原升高，临床与影像检查疑为前列腺癌。穿刺活体组织检查见大片组织细胞样细胞，细胞质丰富、浅染；细胞内、外可见特征性的Michaelis-Gutmann小体，von Kossa钙染色、普鲁士蓝铁染色和高碘酸希夫染色阳性。结论前列腺软斑症较少见，临床、影像与病理学上均要与前列腺癌鉴别，知晓该病并熟悉其病理特征是正确诊断的关键。

Citation： 翁欣, 陈铌, 龚静, 陈雪芹, 聂玲, 周桥. 前列腺软斑症病例报道和文献复习. West China Medical Journal, 2015, 30(11): 2121-2123. doi: 10.7507/1002-0179.20150600 Copy

1.	Michaelis L, Gutmann C. Ueber einschlusse in blasentumoren[J]. Z Clin Med, 1902, 47:208-215.
2.	Carruthers NC. Malakoplakia:report of a case[J]. Can J Surg, 1959, 2(2):213-214.
3.	Alpern HD. Malakoplakia of the prostate[J]. Int Urol Nephrol, 1991, 23(3):257-259.
4.	Ristić-Petrović A, Stojnev S, Janković-Velicković L, et al. Malakoplakia mimics urinary bladder cancer:a case report[J]. Vojnosanit Pregl, 2013, 70(6):606-608.
5.	Solakoglu Kahraman D, Sayhan S, Diniz G, et al. A pitfall in transrectal prostate biopsy:malakoplakia evaluation of two cases based on the literature review[J]. Case Rep Pathol, 2014, 2014:150972.
6.	Goldman RL. A case of malacoplakia with involvement of the prostate gland[J]. J Urol, 1965, 93:407-410.
7.	Hoffmann E, Garrido M. Malakoplakia of the prostate:report of a case[J]. J Urol, 1964, 92:311-313.
8.	Mcclure J. Malakoplakia of the prostate:a report of two cases and a review of the literature[J]. J Clin Pathol, 1979, 32(6):629-632.
9.	Saraf P, Disant’agnese P, Valvo J, et al. An unusual case of malacoplakia involving the testis and prostate[J]. J Urol, 1983, 129(1):149-151.
10.	Nonomura A, Kono N, Takazakura E, et al. Renal and prostatic malakoplakia associated with submassive hepatic necrosis. A case report with immunocytochemical, ultrastructural and X-ray analytical observations[J]. Acta Pathol Jpn, 1986, 36(8):1251-1262.
11.	Long JP, Althausen AF. Malacoplakia:a 25-year experience with a review of the literature[J]. J Urol, 1989, 141(6):1328-1331.
12.	Konnak JW, Hart WR. Malacoplakia of the prostate in an immunosuppressed patient[J]. J Urol, 1976, 116(6):830-832.
13.	Ifudu O, Delaney VB. Malacoplakia of the prostate in a renal transplant recipient. A complicated course[J]. ASAIO J, 1994, 40(2):238-240.
14.	Morgan TA, Rabban JT, Filly RA. Testicular malakoplakia:a rare sonographic mimic of malignancy[J]. J Clin Ultrasound, 2015, 43(3):199-202.
15.	Yousef GM, Naghibi B, Hamodat MM. Malakoplakia outside the urinary tract[J]. Arch Pathol Lab Med, 2007, 131(2):297-300.
16.	Hyun KH, Shin HD, Kim DH. Malakoplakia in a healthy young female patient[J]. Korean J Intern Med, 2013, 28(4):475-480.
17.	Guner G, Akdogan B, Baydar DE. Malakoplakia of prostate as a complication of transrectal needle biopsy[J]. Can J Urol, 2012, 19(1):6124-6127.
18.	Thrasher JB, Sutherland RS, Limoge JP, et al. Transrectal ultrasound and biopsy in diagnosis of malakoplakia of prostate[J]. Urology, 1992, 39(3):262-265.
19.	Wagner D, Joseph J, Huang J, et al. Malakoplakia of the prostate on needle core biopsy:a case report and review of the literature[J]. Int J Surg Pathol, 2007, 15(1):86-89.
20.	Tisseau L, Zini L, Lemaitre L, et al. Prostatic malacoplakia:report of 3 cases[J]. Prog Urol, 2000, 10(4):597-599.
21.	Niemierko M, Kuzaka B. malacoplakia of the prostate[J]. Przegl Lek, 2005, 62(8):825-826.
22.	Koga S, Arakaki Y, Matsuoka M, et al. Malakoplakia of prostate[J]. Urology, 1986, 27(2):160-161.
23.	Sarma HN, Ramesh K, Al Fituri O, et al. Malakoplakia of the prostate gland——report of two cases and review of the literature[J]. Scand J Urol Nephrol, 1996, 30(2):155-157.
24.	张洪宪, 马潞林, 杨邵敏, 等. 前列腺软斑病1例报告[J]. 北京大学学报:医学版, 2011, 43(4):620-622.

1. Michaelis L, Gutmann C. Ueber einschlusse in blasentumoren[J]. Z Clin Med, 1902, 47:208-215.
2. Carruthers NC. Malakoplakia:report of a case[J]. Can J Surg, 1959, 2(2):213-214.
3. Alpern HD. Malakoplakia of the prostate[J]. Int Urol Nephrol, 1991, 23(3):257-259.
4. Ristić-Petrović A, Stojnev S, Janković-Velicković L, et al. Malakoplakia mimics urinary bladder cancer:a case report[J]. Vojnosanit Pregl, 2013, 70(6):606-608.
5. Solakoglu Kahraman D, Sayhan S, Diniz G, et al. A pitfall in transrectal prostate biopsy:malakoplakia evaluation of two cases based on the literature review[J]. Case Rep Pathol, 2014, 2014:150972.
6. Goldman RL. A case of malacoplakia with involvement of the prostate gland[J]. J Urol, 1965, 93:407-410.
7. Hoffmann E, Garrido M. Malakoplakia of the prostate:report of a case[J]. J Urol, 1964, 92:311-313.
8. Mcclure J. Malakoplakia of the prostate:a report of two cases and a review of the literature[J]. J Clin Pathol, 1979, 32(6):629-632.
9. Saraf P, Disant’agnese P, Valvo J, et al. An unusual case of malacoplakia involving the testis and prostate[J]. J Urol, 1983, 129(1):149-151.
10. Nonomura A, Kono N, Takazakura E, et al. Renal and prostatic malakoplakia associated with submassive hepatic necrosis. A case report with immunocytochemical, ultrastructural and X-ray analytical observations[J]. Acta Pathol Jpn, 1986, 36(8):1251-1262.
11. Long JP, Althausen AF. Malacoplakia:a 25-year experience with a review of the literature[J]. J Urol, 1989, 141(6):1328-1331.
12. Konnak JW, Hart WR. Malacoplakia of the prostate in an immunosuppressed patient[J]. J Urol, 1976, 116(6):830-832.
13. Ifudu O, Delaney VB. Malacoplakia of the prostate in a renal transplant recipient. A complicated course[J]. ASAIO J, 1994, 40(2):238-240.
14. Morgan TA, Rabban JT, Filly RA. Testicular malakoplakia:a rare sonographic mimic of malignancy[J]. J Clin Ultrasound, 2015, 43(3):199-202.
15. Yousef GM, Naghibi B, Hamodat MM. Malakoplakia outside the urinary tract[J]. Arch Pathol Lab Med, 2007, 131(2):297-300.
16. Hyun KH, Shin HD, Kim DH. Malakoplakia in a healthy young female patient[J]. Korean J Intern Med, 2013, 28(4):475-480.
17. Guner G, Akdogan B, Baydar DE. Malakoplakia of prostate as a complication of transrectal needle biopsy[J]. Can J Urol, 2012, 19(1):6124-6127.
18. Thrasher JB, Sutherland RS, Limoge JP, et al. Transrectal ultrasound and biopsy in diagnosis of malakoplakia of prostate[J]. Urology, 1992, 39(3):262-265.
19. Wagner D, Joseph J, Huang J, et al. Malakoplakia of the prostate on needle core biopsy:a case report and review of the literature[J]. Int J Surg Pathol, 2007, 15(1):86-89.
20. Tisseau L, Zini L, Lemaitre L, et al. Prostatic malacoplakia:report of 3 cases[J]. Prog Urol, 2000, 10(4):597-599.
21. Niemierko M, Kuzaka B. malacoplakia of the prostate[J]. Przegl Lek, 2005, 62(8):825-826.
22. Koga S, Arakaki Y, Matsuoka M, et al. Malakoplakia of prostate[J]. Urology, 1986, 27(2):160-161.
23. Sarma HN, Ramesh K, Al Fituri O, et al. Malakoplakia of the prostate gland——report of two cases and review of the literature[J]. Scand J Urol Nephrol, 1996, 30(2):155-157.
24. 张洪宪, 马潞林, 杨邵敏, 等. 前列腺软斑病1例报告[J]. 北京大学学报:医学版, 2011, 43(4):620-622.

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前列腺软斑症病例报道和文献复习

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