<trans-title xml:lang="en"/>_West China Medical Journal

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¹ , ¹ , ¹ ,  ²

1. ;
2. ;

Corresponding author：

, Email: drjiangxj@live.cn

Keywords：

沙眼衣原体; 解脲支原体; 异位妊娠

DOI：

10.7507/1002-0179.201508099

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目的探讨沙眼衣原体（Chlamyia trachomatis，CT）、解脲支原体（Ureaplasma urelyticum，UU）感染与异位妊娠的关系。方法收集 2014 年 1 月 1 日—12 月 31 日滨州医学院烟台附属医院收治的 115 例异位妊娠患者为观察组；选取同期因其他疾病住院，术中输卵管外观无异常或切除输卵管病理检查未见异常者为对照组，共 120 例。分别取其宫颈管分泌物行 CT 抗原检测以及解脲支原体培养，计算观察组和对照组 CT 感染率、UU 感染率和 CT+UU 联合感染率，并比较两组间的差异。结果观察组 CT 感染率为 18.26%（21/115），UU 感染率为 49.57%（57/115），CT+UU 联合感染率为 10.43%（12/115），分别高于对照组的 CT 感染率 [8.33%（10/120）]、UU 感染率 [25.83%（31/120）]、CT+UU 联合感染率 [2.50%（3/120）]，两组 CT 感染率、UU 感染率及 CT+UU 联合感染率比较差异均有统计学意义（P<0.05）。结论 CT、UU 与异位妊娠的发生密切相关。

Citation： 宋玉春, 王海宁, 李宁, 姜晓晶. . West China Medical Journal, 2017, 32(2): 220-222. doi: 10.7507/1002-0179.201508099 Copy

1.	Li C, Meng CX, Zhao WH, et al. Risk factors for ectopic pregnancy in women with planned pregnancy: a case-control study. Eur J Obstet Gynecol Reprod Biol, 2014, 181(1): 176-182.
2.	Mardh PA. Tubal fact or infertility, with special regard to chlamydial salpingitis. Curr Opin Infect Dis, 2004, 17(1): 49-52.
3.	Waites KB, Katz B, Schelonka RL. Mycoplasmas and ureaplasmas as neonatal pathogens. Clin Microbiol Rev, 2005, 18(4): 757-789.
4.	Rana P, Kazmi I, Singh R, et al. Ectopic pregnancy: a review. Arch Gynecol Obstet, 2013, 288(4): 747-757.
5.	许旭, 许良智. 不同部位输卵管不孕的临床循症治疗. 华西医学, 2013, 28(6): 963-966.
6.	Gradison M. Pelvic inflammatory disease. Am Fam Physician, 2012, 85(8): 791-796.
7.	黄婉茹. 支原体、衣原体感染与输卵管妊娠关系的临床观察. 吉林医学, 2014, 35(28): 6215-6216.
8.	Ljubin-Sternak S, Meštrović T. Chlamydia trachomatis and genital mycoplasmas: pathogens with an impact on human reproductive health. J Pathog, 2014, 2014: 183167.
9.	Jaton K, Greub G. Chlamydia: diagnostic and treatment. Rev Med Suisse, 2005, 1(13): 901-903.
10.	Torrone E, Papp J, Weinstock H, et al. Prevalence of Chlamydia trachomatis genital infection among persons aged 14-39 years--United States, 2007-2012. MMWR Morb Mortal Wkly Rep, 2014, 63(38): 834-838.
11.	Baczynska A, Funch P, Fedder J, et al. Morphology of human fallopian tubes after infection with Mycoplasma grenitalium and Mycoplasma homins--in vitro organ culture study. Human Reprod, 2007, 22(4): 968-979.
12.	Sweet RL. Treatment of acute pelvic inflammatory disease. Infect Dis Obstet Gynecol, 2011, 2011: 561909.
13.	Karaer A, Mert I, Cavkaytar S, et al. Serological investigation of the role of selected sexually transmitted infections in the aetiology of ectopic pregnancy. Eur J Contracep Reprod Health Care, 2013, 18(1): 68-74.
14.	梁家智, 蒲杰, 郑殊娟, 等. 异位妊娠危险因素的分析. 华西医学, 2008, 23(5): 1017-1018.
15.	谢翠华. 宫颈解脲支原体感染与输卵管妊娠的关系探讨. 实用心脑肺血管病杂志, 2008, 16(10): 36.
16.	漆洪波, 刘先俊, 顾美礼, 等. 输卵管妊娠患者沙眼衣原体及解脲脲原体检测. 中华妇产科杂志, 1997, 32(2): 93-96.
17.	芦笛, 白伶俐, 任永变. 解脲支原体、沙眼衣原体感染与异位妊娠的相关性研究. 中国性科学, 1994, 25(6): 51-52.

1. Li C, Meng CX, Zhao WH, et al. Risk factors for ectopic pregnancy in women with planned pregnancy: a case-control study. Eur J Obstet Gynecol Reprod Biol, 2014, 181(1): 176-182.
2. Mardh PA. Tubal fact or infertility, with special regard to chlamydial salpingitis. Curr Opin Infect Dis, 2004, 17(1): 49-52.
3. Waites KB, Katz B, Schelonka RL. Mycoplasmas and ureaplasmas as neonatal pathogens. Clin Microbiol Rev, 2005, 18(4): 757-789.
4. Rana P, Kazmi I, Singh R, et al. Ectopic pregnancy: a review. Arch Gynecol Obstet, 2013, 288(4): 747-757.
5. 许旭, 许良智. 不同部位输卵管不孕的临床循症治疗. 华西医学, 2013, 28(6): 963-966.
6. Gradison M. Pelvic inflammatory disease. Am Fam Physician, 2012, 85(8): 791-796.
7. 黄婉茹. 支原体、衣原体感染与输卵管妊娠关系的临床观察. 吉林医学, 2014, 35(28): 6215-6216.
8. Ljubin-Sternak S, Meštrović T. Chlamydia trachomatis and genital mycoplasmas: pathogens with an impact on human reproductive health. J Pathog, 2014, 2014: 183167.
9. Jaton K, Greub G. Chlamydia: diagnostic and treatment. Rev Med Suisse, 2005, 1(13): 901-903.
10. Torrone E, Papp J, Weinstock H, et al. Prevalence of Chlamydia trachomatis genital infection among persons aged 14-39 years--United States, 2007-2012. MMWR Morb Mortal Wkly Rep, 2014, 63(38): 834-838.
11. Baczynska A, Funch P, Fedder J, et al. Morphology of human fallopian tubes after infection with Mycoplasma grenitalium and Mycoplasma homins--in vitro organ culture study. Human Reprod, 2007, 22(4): 968-979.
12. Sweet RL. Treatment of acute pelvic inflammatory disease. Infect Dis Obstet Gynecol, 2011, 2011: 561909.
13. Karaer A, Mert I, Cavkaytar S, et al. Serological investigation of the role of selected sexually transmitted infections in the aetiology of ectopic pregnancy. Eur J Contracep Reprod Health Care, 2013, 18(1): 68-74.
14. 梁家智, 蒲杰, 郑殊娟, 等. 异位妊娠危险因素的分析. 华西医学, 2008, 23(5): 1017-1018.
15. 谢翠华. 宫颈解脲支原体感染与输卵管妊娠的关系探讨. 实用心脑肺血管病杂志, 2008, 16(10): 36.
16. 漆洪波, 刘先俊, 顾美礼, 等. 输卵管妊娠患者沙眼衣原体及解脲脲原体检测. 中华妇产科杂志, 1997, 32(2): 93-96.
17. 芦笛, 白伶俐, 任永变. 解脲支原体、沙眼衣原体感染与异位妊娠的相关性研究. 中国性科学, 1994, 25(6): 51-52.

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