Clinical characteristics of pregnant women with acute diarrhea_West China Medical Journal

Authors：

 JIJing ¹ , ZHENGTinghua ²

1. Department of Infectious Diseases, Kailuan General Hospital, Tangshan, Hebei 063000, P. R. China;
2. Department of Obstetrics, Maternal and Child Health Hospital, Tangshan, Heibei 063000, P. R. China;

Corresponding author：

JIJing, Email: jj5877204@163.com

Keywords：

Pregnancy; Acute diarrhea; Clinical characteristics

DOI：

10.7507/1002-0179.201511106

Video：

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Objective To analyze the clinical features and outcomes of pregnant women with acute diarrhea. Methods We collected the clinical data of 133 pregnant women with acute diarrhea (group A) admitted into Tangshan Maternal and Child Health Hospital and Kailuan General Hospital between June 2009 and June 2015. Another 100 acute diarrhea patients without pregnancy (group B) and 100 pregnant women without acute diarrhea (group C) were regarded as controls. All the patients’ medical history, symptoms and signs, laboratory examination results, diagnosis and treatment, termination of pregnancy and pregnancy outcomes were retrospectively analyzed. Results The average age of group A patients was (29.72±5.19) years old, and 83.46% of them came to hospital within 24 hours. There were significant differences in vomiting, abdominal pain, white blood cells, neutrophils, C-reactive protein, white blood cells in the feces, fibrinogen, prothrombin time, activated partial prothrombin time, thrombin time and the recovery time of the laboratory indicators between group A and group B (P<0.05). The neonatal weight of group A was lower than that of group C, and the difference was statistically significant (P<0.05). Regression analysis showed that hemoglobin and albumin had significant influence on acute diarrhea during pregnancy (P<0.05). Conclusion Pregnancy with acute diarrhea is a kind of severe obstetric complication, which may lead to adverse pregnancy.

Citation： JIJing, ZHENGTinghua. Clinical characteristics of pregnant women with acute diarrhea. West China Medical Journal, 2017, 32(1): 37-41. doi: 10.7507/1002-0179.201511106 Copy

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1. 李迪, 潘晓娟, 贺娟. 双歧三联活菌片与蒙脱石散治疗妊娠腹泻的随机对照研究. 四川医学, 2011, 32(4): 506-507.
2. 丰有吉, 沈铿. 妇产科学. 2版. 北京: 人民卫生出版社, 2010: 162.
3. 缪晓辉, 冉陆, 张文宏, 等. 成人急性感染性腹泻诊疗专家共识. 中华消化杂志, 2013, 33(12): 793-802.
4. Friese K, Melchert F. Arzneimitteltherapie in der frauenh-eilkunde. Berlin: Wissenschaftliche, 2002.
5. Mavziutov AR, Bondarenko KR, Enikeev AN,et al. Systemic endotoxinemia as a pathogenetic factor of pregnancy complication. Zh Mikrobiol Epidemiol Immunobiol, 2012(5): 16-21.
6. Logan S, Price L. Infectious disease in pregnancy. Obstet Gynaecol Reprod Med, 2011, 21(12): 331-338.
7. Mcgready R, Wuthiekanun V, Ashley EA,et al. Diagnostic and treatment difficulties of pyelonephritis in pregnancy in resource-limited settings. Am J Trop Med Hyg, 2010, 83(6): 1322-1329.
8. Mylonas I, Dian D, Friese K. Antibiotikatherapie in der schwangerschaft. Der Gynäkologe, 2005, 38(9): 761-770.
9. 高涛. 《金医要略》“妊娠病篇”沿革与现代应用价值探讨. 杭州: 浙江中医药大学, 2016: 10-12.
10. 孙嫣. 常美安治疗妊娠期感染性腹泻的临床观察. 山东医药, 2013, 53 (17): 81-82.
11. 黄小萍. 妊娠期妇女用药安全性探讨. 中国药房, 2007, 18(35): 2799-2800.
12. 玛莉, 邢爱耘, 战军, 等. 609 例死胎相关因素分析. 华西医学, 2013, 28(1): 61.
13. 赵霞, 李洁. 妊娠中期妇女血清铁蛋白水平与妊娠中、晚期贫血相关性研究. 中国药业, 2014, 23(7): 79-80.
14. 景小凡, 柳园, 饶志勇, 等. 妊娠期糖尿病对母婴结局的影响分析. 华西医学, 2016, 31(2): 301.

West China Medical Journal

Clinical characteristics of pregnant women with acute diarrhea

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