Comparison of Application and Nursing between Continuous Hyperthermic Peritoneal Perfusion Chemotherapy and Intravenous Chemotherapy for Advanced Gastric Cancer Patients_West China Medical Journal

Authors：

 GaoHuijun ¹ ,  GanJianhui ²

1. Operation Room;Tangshan People's Hospital Affiliated to North China University of Science and Technology, Tangshan, Hebei 063000, P. R. China;
2. Department of Anesthesiology;Tangshan People's Hospital Affiliated to North China University of Science and Technology, Tangshan, Hebei 063000, P. R. China;

Corresponding author：

GanJianhui, Email: gjh71@163.com

Keywords：

Nursing; Advanced gastric cancer; Continuous hyperthermic peritoneal perfusion; Chemotherapy

DOI：

10.7507/1002-0179.201600434

Video：

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Objective To compare the clinical effects of continuous hyperthermic peritoneal perfusion chemotherapy (CHPPC) and intravenous chemotherapy for advanced gastric cancer patients, and find better nursing methods. Methods Sixty advanced gastric cancer patients who underwent chemotherapy between June 2013 and June 2014 were divided into CHPPC group (group C, n=30) and intravenous chemotherapy group (group V, n=30). We recorded the nursing methods for both the two groups, patients' satisfaction to the nursing and treatment, peritoneal metastasis rate and quality of life during the chemotherapy. Results The life quality in group V was lower than that in group C (P<0.05). The differences in patients' satisfaction rate, peritoneal metastasis rate, and one-year survival rate were not significantly different between the two groups (P>0.05). Conclusion For patients with advanced gastric cancer requiring chemotherapy, in spite of higher cost and more complicated operations, CHPPC is superior in lower adverse events rate, better quality of life during chemotherapy and doesn't decrease patients' satisfaction to the nursing and treatment.

Citation： GaoHuijun, GanJianhui. Comparison of Application and Nursing between Continuous Hyperthermic Peritoneal Perfusion Chemotherapy and Intravenous Chemotherapy for Advanced Gastric Cancer Patients. West China Medical Journal, 2016, 31(9): 1589-1591. doi: 10.7507/1002-0179.201600434 Copy

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1. 龚海云. 70例中晚期恶性肿瘤患者全身热疗的观察与护理[J]. 当代护士:学术版, 2008(3):49-51.
2. 马蕊. 恶性肿瘤患者全身热疗护理体会[J]. 中国现代药物应用, 2010, 4(11):180-181.
3. 赵改梅, 方慧. 恶性肿瘤患者全身热疗的护理体会[J]. 实用医药杂志, 2008, 25(8):962-963.
4. 黄丽君, 徐惠芳, 宋俊莹, 等. 腹部中晚期恶性肿瘤热疗的护理探讨[J]. 中国临床保健杂志, 2015, 5(2):214-215.
5. 郑剑菁. 晚期肿瘤患者深部热疗护理体会[J]. 福建医药杂志, 2014, 36(1):172-173.
6. 颉宝平, 李征, 姚南, 等. 化疗联合热疗治疗晚期大肠癌疗效及安全性的Meta分析[J]. 中国循证医学杂志, 2013, 13(3):352-357.
7. Willcox CR, Pitard V, Netzer S, et al. Cytomegalovirus and tumor stress surveillance by binding of a human γδ T cell antigen receptor to endothelial protein C receptor[J]. Nat Immunol, 2012, 13(9):872-879.
8. Haber JS, Banu MA, Ray A, et al. Industry progress report on neuro-oncology:a biotech update[J]. J Neurooncol, 2013, 112(2):315-321.
9. Saito M, Yano K, Kamigaki T, et al. A patient with scirrhous stomach cancer treated with combination of hyperthermotherapy and 5-aminolevulinic acid (ALA)[J]. Anticancer Res, 2013, 33(7):2957-2963.
10. 闫向勇, 刘文超. 热疗在肿瘤治疗中的研究进展[J]. 世界中西医结合杂志, 2014, 9(2):213-216.
11. 张佳慧, 秦丽娟. 肿瘤热疗的研究进展[J]. 实用心脑肺血管病杂志, 2012, 20(9):1424-1426.
12. 许士珍, 宋春燕, 王翠英. 康艾注射液联合热化疗治疗恶性胸腔积液80例[J]. 临床荟萃, 2013, 28(11):1278-1279.
13. 黎玉梅, 彭美芳, 黄颖华, 等. ET-SPACE-Ⅰ型全身热疗系统治疗恶性肿瘤护理体会[J]. 护士进修杂志, 2003, 18(11):988-990.
14. 陈艳芳. 恶性肿瘤患者行全身热疗联合化疗预防烫伤的护理[J]. 南方护理学报, 2005, 12(7):46-47.
15. 唐雯. 浅析全身热疗联合化疗治疗晚期肿瘤110例[J]. 中国医药指南, 2013, 11(30):103-104.

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West China Medical Journal

Comparison of Application and Nursing between Continuous Hyperthermic Peritoneal Perfusion Chemotherapy and Intravenous Chemotherapy for Advanced Gastric Cancer Patients

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