Investigation on antihypertensive therapy for hypertension patients from plateau area_West China Medical Journal

Authors：

ZHAO Liming ¹ , LI Xiaoping ¹ , ZHOU Yao ¹ , LI Hongwei ¹ , HE Bin ¹ , LIU Lanxin ¹ , DU Wei ¹ , WU Yong ¹ , MA Min ² , HUANG Fangyang ² , FU Yongxing ² ,  ZHU Ye ²

1. Department of Cardiovascular Medicine, Hospital of Chengdu Office of People’s Government of Tibetan Autonomous Region, Chengdu, Sichuan 610041, P. R. China;
2. Department of Cardiology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;

Corresponding author：

ZHU Ye, Email: zhuye1974@163.com

Keywords：

Plateau; Hypertension; Antihypertensive

DOI：

10.7507/1002-0179.201603183

Video：

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Objective To explore the effect of antihypertensive therapy for hypertension patients from plateau area. Method A retrospective analysis of medical records for Tibetan patients with hypertension from October to December 2013 in Hospital of Chengdu Office of People’s Government of Tibetan Autonomous Region. Results The study recruited 165 patients. The rate of treatment, control, and compliance of hypertension patients were 86.7% (143/165), 23.8% (34/143), 43.4% (62/143), respectively. The main characteristics of hypertension treatment were higher proportions of single-drug therapy (81.1%, 116/143); among those the Tibetan drug (24.1%), calcium channel blockers (21.6%), diuretics (19.0%), and traditional compound preparation (18.1%) were most commonly used in the antihypertensive therapy. Conclusions The rate of treatment was high, but the rate of control and compliance were low in Tibetan patients with hypertension. It was necessary to carry out hypertension education to patients and strengthen the training of doctors at the plateau.

Citation： ZHAO Liming, LI Xiaoping, ZHOU Yao, LI Hongwei, HE Bin, LIU Lanxin, DU Wei, WU Yong, MA Min, HUANG Fangyang, FU Yongxing, ZHU Ye. Investigation on antihypertensive therapy for hypertension patients from plateau area. West China Medical Journal, 2018, 33(3): 317-320. doi: 10.7507/1002-0179.201603183 Copy

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1. Lloyd-Jones D, Adams R, Carnethon M, et al. Heart disease and stroke statistics——2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation, 2009, 119(3): e21-181.
2. 中华人民共和国国家卫生和计划生育委员会. 2011中国卫生统计年鉴. (2011-01-16)[2016-03-11]. http://www.nhfpc.gov.cn/ htmlfiles/zwgkzt/ptjnj/year2011/index2011.html.
3. Sun SF. Epidemiology of hypertension on the Tibetan Plateau. Hum Biol, 1986, 58(4): 507-515.
4. Li K, Liang Y, Sun Y, et al. The relationship between polymorphisms at 17 gene sites and hypertension among the Aboriginal Tibetan People. Biomed Environ Sci, 2012, 25(5): 526-532.
5. Schapira MM, Fletcher KE, Hayes A, et al. The development and validation of the hypertension evaluation of lifestyle and management knowledge scale. J Clin Hypertens (Greenwich), 2012, 14(7): 461-466.
6. 中国高血压防治指南修订委员会. 中国高血压防治指南2010. 中国医学前沿杂志: 电子版, 2011, 3(5): 42-93.
7. Zheng X, Yao DK, Zhuo-Ma CR, et al. Prevalence, self-awareness, treatment, and control of hypertension in Lhasa, Tibet. Clin Exp Hypertens, 2012, 34(5): 328-333.
8. Yang S, Liu S, Wang Y, et al. High blood pressure in Chinese ethnic minorities: report from rural Yunnan province. Am J Hypertens. 2011, 24(11): 1209-1214.
9. Zhao X, Li S, Ba S, et al. Prevalence, awareness, treatment, and control of hypertension among herdsmen living at 4,300 m in Tibet. Am J Hypertens, 2012, 25(5): 583-589.
10. Sherpa LY, Stigum H, Chongsuvivatwong V, et al. Prevalence of metabolic syndrome and common metabolic components in high altitude farmers and herdsmen at 3700 m in Tibet. High Alt Med Biol, 2013, 14(1): 37-44.
11. Mingji C, Onakpoya IJ, Perera R, et al. Relationship between altitude and the prevalence of hypertension in Tibet: a systematic review. Heart, 2015, 101(13): 1054-1060.
12. Liu L, Liu L, Ding Y, et al. Ethnic and environmental differences in various markers of dietary intake and blood pressure among Chinese Han and three other minority peoples of China: results from the WHO Cardiovascular Diseases and Alimentary Comparison (CARDIAC) Study. Hypertens Res, 2001, 24(3): 315-322.
13. Xu S, Jiayong Z, Li B, et al. Prevalence and clustering of cardiovascular disease risk factors among Tibetan adults in China: a population-based study. PLoS One, 2015, 10(6): e0129966.
14. 黄宇, 陈彦, 王张, 等. 基于药品说明书的规范化开展藏成药标准化研究——以七十味珍珠丸为例. 成都: 2011全国藏医药学术研讨会, 2011: 414-421.

West China Medical Journal

Investigation on antihypertensive therapy for hypertension patients from plateau area

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