Hot topics on the diagnosis and antimicrobial therapy of ventilator-associated pneumonia_West China Medical Journal

Authors：

ZHANG Jing ¹ ,  QU Jieming ²

1. Department of Pulmonay Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, P. R. China;
2. Department of Pulmonary Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200032, P. R. China;

Corresponding author：

QU Jieming, Email: jmqu0906@163.com

Keywords：

Ventilator-associated pneumonia; Diagnosis; Antimcrobial therapy

DOI：

10.7507/1002-0179.201710185

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Hot topics on the diagnosis and antimicrobial therapy of ventilator-associated pneumonia, including clinical diagnostic criteria, evaluation of biomarkers, ventilator associated events, clinical pulmonary infection score, ventilator-associated tracheobronchitis, microbiological diagnosis and duration of therapy were discussed. The viewpoints in the guidelines of America, Europe and Japan were also reviewed.

Citation： ZHANG Jing, QU Jieming. Hot topics on the diagnosis and antimicrobial therapy of ventilator-associated pneumonia. West China Medical Journal, 2018, 33(1): 19-22. doi: 10.7507/1002-0179.201710185 Copy

1.	Kalil AC, Metersky ML, Klompas M, et al. Executive summary: management of adults with hospital-acquired and ventilator-associated pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society. Clin Infect Dis, 2016, 63(5): 575-582.
2.	Torres A, Niederman MS, Chastre J, et al. International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia: guidelines for the management of hospital-acquired pneumonia (HAP)/ventilator-associated pneumonia (VAP) of the European Respiratory Society (ERS), European Society of Intensive Care Medicine (ESICM), European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and Asociación Latinoamericana del Tórax (ALAT). Eur Respir J, 2017, 50(3): 1700582.
3.	日本呼吸器学会. 成人肺炎診療ガイドライン2017. (2017-04-20)[2017-12-18]. http://jrsec-sh.sv1.allin1.jp/goods/ 1491290825903/.
4.	Fàbregas N, Ewig S, Torres A, et al. Clinical diagnosis of ventilator associated pneumonia revisited: comparative validation using immediate post-mortem lung biopsies. Thorax, 1999, 54(10): 867-873.
5.	Sager R, Kutz A, Mueller B, et al. Procalcitonin-guided diagnosis and antibiotic stewardship revisited. BMC Med, 2017, 15(1): 15.
6.	Centers for Disease Control and Prevention. Ventilator-associated event (VAE) . (2017-01-01)[2017-10-31]. https://www.cdc.gov/ nhsn/pdfs/pscmanual/10-vae_final.pdf.
7.	Guillamet CV, Kollef MH. Ventilator associated pneumonia in the ICU: where has it gone? Curr Opin Pulm Med, 2015, 21(3): 226-231.
8.	Nair GB, Niederman MS. Ventilator-associated pneumonia: present understanding and ongoing debates. Intensive Care Med, 2015, 41(1): 34-48.
9.	Shan J, Chen HL, Zhu JH. Diagnostic accuracy of clinical pulmonary infection score for ventilator-associated pneumonia: a meta-analysis. Respir Care, 2011, 56(8): 1087-1094.
10.	Nseir S, Di Pompeo C, Soubrier S, et al. Effect of ventilator-associated tracheobronchitis on outcome in patients without chronic respiratory failure: a case-control study. Crit Care, 2005, 9(3): R238-R245.
11.	Martin-Loeches I, Povoa P, Rodríguez A, et al. Incidence and prognosis of ventilator-associated tracheobronchitis (TAVeM): a multicentre, prospective, observational study. Lancet Respir Med, 2015, 3(11): 859-868.
12.	Nseir S, Martin-Loeches I, Makris D, et al. Impact of appropriate antimicrobial treatment on transition from ventilator-associated tracheobronchitis to ventilator-associated pneumonia. Crit Care, 2014, 18(3): R129.
13.	Ramirez P, Lopez-Ferraz C, Gordon M, et al. From starting mechanical ventilation to ventilator-associated pneumonia, choosing the right moment to start antibiotic treatment. Crit Care, 2016, 20(1): 169.
14.	Yu Y, Zhu C, Liu C, et al. How to remove the grey area between ventilator-associated pneumonia and ventilator-associated tracheobronchitis?. Crit Care, 2017, 21(1): 165.
15.	Pugh R, Grant C, Cooke RP, et al. Short-course versus prolonged-course antibiotic therapy for hospital-acquired pneumonia in critically ill adults. Cochrane Database Syst Rev, 2011(10): CD007577.
16.	Larsson J, Itenov TS, Bestle MH. Risk prediction models for mortality in patients with ventilator-associated pneumonia: a systematic review and meta-analysis. J Crit Care, 2017, 37: 112-118.

1. Kalil AC, Metersky ML, Klompas M, et al. Executive summary: management of adults with hospital-acquired and ventilator-associated pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society. Clin Infect Dis, 2016, 63(5): 575-582.
2. Torres A, Niederman MS, Chastre J, et al. International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia: guidelines for the management of hospital-acquired pneumonia (HAP)/ventilator-associated pneumonia (VAP) of the European Respiratory Society (ERS), European Society of Intensive Care Medicine (ESICM), European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and Asociación Latinoamericana del Tórax (ALAT). Eur Respir J, 2017, 50(3): 1700582.
3. 日本呼吸器学会. 成人肺炎診療ガイドライン2017. (2017-04-20)[2017-12-18]. http://jrsec-sh.sv1.allin1.jp/goods/ 1491290825903/.
4. Fàbregas N, Ewig S, Torres A, et al. Clinical diagnosis of ventilator associated pneumonia revisited: comparative validation using immediate post-mortem lung biopsies. Thorax, 1999, 54(10): 867-873.
5. Sager R, Kutz A, Mueller B, et al. Procalcitonin-guided diagnosis and antibiotic stewardship revisited. BMC Med, 2017, 15(1): 15.
6. Centers for Disease Control and Prevention. Ventilator-associated event (VAE) . (2017-01-01)[2017-10-31]. https://www.cdc.gov/ nhsn/pdfs/pscmanual/10-vae_final.pdf.
7. Guillamet CV, Kollef MH. Ventilator associated pneumonia in the ICU: where has it gone? Curr Opin Pulm Med, 2015, 21(3): 226-231.
8. Nair GB, Niederman MS. Ventilator-associated pneumonia: present understanding and ongoing debates. Intensive Care Med, 2015, 41(1): 34-48.
9. Shan J, Chen HL, Zhu JH. Diagnostic accuracy of clinical pulmonary infection score for ventilator-associated pneumonia: a meta-analysis. Respir Care, 2011, 56(8): 1087-1094.
10. Nseir S, Di Pompeo C, Soubrier S, et al. Effect of ventilator-associated tracheobronchitis on outcome in patients without chronic respiratory failure: a case-control study. Crit Care, 2005, 9(3): R238-R245.
11. Martin-Loeches I, Povoa P, Rodríguez A, et al. Incidence and prognosis of ventilator-associated tracheobronchitis (TAVeM): a multicentre, prospective, observational study. Lancet Respir Med, 2015, 3(11): 859-868.
12. Nseir S, Martin-Loeches I, Makris D, et al. Impact of appropriate antimicrobial treatment on transition from ventilator-associated tracheobronchitis to ventilator-associated pneumonia. Crit Care, 2014, 18(3): R129.
13. Ramirez P, Lopez-Ferraz C, Gordon M, et al. From starting mechanical ventilation to ventilator-associated pneumonia, choosing the right moment to start antibiotic treatment. Crit Care, 2016, 20(1): 169.
14. Yu Y, Zhu C, Liu C, et al. How to remove the grey area between ventilator-associated pneumonia and ventilator-associated tracheobronchitis?. Crit Care, 2017, 21(1): 165.
15. Pugh R, Grant C, Cooke RP, et al. Short-course versus prolonged-course antibiotic therapy for hospital-acquired pneumonia in critically ill adults. Cochrane Database Syst Rev, 2011(10): CD007577.
16. Larsson J, Itenov TS, Bestle MH. Risk prediction models for mortality in patients with ventilator-associated pneumonia: a systematic review and meta-analysis. J Crit Care, 2017, 37: 112-118.

West China Medical Journal

Hot topics on the diagnosis and antimicrobial therapy of ventilator-associated pneumonia

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content