Risk factors of postoperative anxiety in patients with pancreatic cancer undergoing total pancreatectomy_West China Medical Journal

Authors：

XU Qiaoyu ¹ , ZHANG Hao ² , GONG Shu ² , LI Kezhou ² ,  LIU Xubao ²

1. Department of Out-patient, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;
2. Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;

Corresponding author：

LIU Xubao, Email: huaxipancreaslxb@163.com

Keywords：

Total pancreatectomy; Pancreatic cancer; Perioperative period; Postoperative anxiety; Risk factor

DOI：

10.7507/1002-0179.201803037

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Objective To explore the risk factors of postoperative anxiety in patients with pancreatic cancer undergoing total pancreatectomy. Methods A total of 31 patients who underwent total pancreatectomy for pancreatic cancer between July 2011 and December 2016 were collected and analyzed in this retrospective study. The patients’ postoperative Self-Rating Anxiety Scale scores were collected, and the exposure factors were analyzed to identify the risk factors of postoperative anxiety through univariate analysis and multiple logistic regression analysis by SPSS 21.0 statistical software. Results In the 31 patients, there were 17 males and 14 females, with an average age of (66.16±9.09) years, an average body mass index of (21.11±3.10) kg/m², and an average postoperative hospital stay of (14.58±7.47) days. There were 23 patients (74.2%) with postoperative anxiety, and 30 patients (96.8%) with hyperglycosemia required insulin therapy. The total perioperative mortality was 3.2%. In the univariate analysis, age (P=0.012), smoking history (P=0.043), preoperative diabetes mellitus (P=0.012), postoperative bile leakage (P=0.043), and postoperative abdominal infection (P=0.026) were related factors of the postoperative anxiety. In the multiple logistic regression analysis, patients without preoperative diabetes was an independent risk factor of postoperative anxiety (P=0.013). Conclusions For patients undergoing total pancreatectomy, it is needed to pay attention to the patients’ postoperative psychological conditions and assess the postoperative anxiety, especially for those without preoperative diabetes. To improve the life quality and long-term survival of these patients, health education and psychological intervention are needed.

Citation： XU Qiaoyu, ZHANG Hao, GONG Shu, LI Kezhou, LIU Xubao. Risk factors of postoperative anxiety in patients with pancreatic cancer undergoing total pancreatectomy. West China Medical Journal, 2018, 33(4): 431-434. doi: 10.7507/1002-0179.201803037 Copy

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2.	Castellanos JA, Merchant NB. Intensity of follow-up after pancreatic cancer resection. Ann Surg Oncol, 2014, 21(3): 747-751.
3.	Reddy SK, Tyler DS, Pappas TN, et al. Extended resection for pancreatic adenocarcinoma. Oncologist, 2007, 12(6): 654-663.
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6.	Suzuki S, Kajiyama H, Takemura A, et al. The clinical outcomes after total pancreatectomy. Dig Surg, 2017, 34(2): 142-150.
7.	Gilliland TM, Villafane-Ferriol N, Shah KP, et al. Nutritional and metabolic derangements in pancreatic cancer and pancreatic resection. Nutrients, 2017, 9(3): E243.
8.	Barreto SG, Windsor JA. Justifying vein resection with pancreatoduodenectomy. Lancet Oncol, 2016, 17(3): E118-E124.
9.	Tong HX, Zhang L, Rong YF, et al. Long-term survival following total pancreatectomy and superior mesenteric-portal vein resection for pancreatic ductal adenocarcinoma: a case report. Oncol Lett, 2015, 9(1): 318-320.
10.	Rockey EW. Total pancreatectomy for carcinoma: case report. Ann Surg, 1943, 118(4):603-611.
11.	Zakaria HM, Stauffer JA, Raimondo M, et al. Total pancreatectomy: short- and long-term outcomes at a high-volume pancreas center. World J Gastrointest Surg, 2016, 8(9): 634-642.
12.	Del Chiaro M, Rangelova E, Segersvard R, et al. Are there still indications for total pancreatectomy?. Updates Surg, 2016, 68(3): 257-263.
13.	丁如梅, 黄建业. 26 例全胰切除术病人的围术期护理. 全科护理, 2013(34): 3178-3180.
14.	谭亚非, 龚姝. 腹腔镜全胰切除术合并 2 型糖尿病患者的围手术期护理一例. 华西医学, 2017, 31(7): 1131-1132.
15.	Bhayani NH, Enomoto LM, Miller JL, et al. Morbidity of total pancreatectomy with islet cell auto-transplantation compared to total pancreatectomy alone. HPB (Oxford), 2014, 16(6): 522-527.
16.	Lightner AM, Glasgow RE, Jordan TH, et al. Pancreatic resection in the elderly. J Am Coll Surg, 2004, 198(5): 697-706.
17.	Parks L, Routt M. Total pancreatectomy with islet cell transplantationfor the treatment of pancreatic cancer. Clin J Oncol Nurs, 2015, 19(4): 479-481.
18.	Ulander K, Grahn G, Sundahl G, et al. Needs and care of patients undergoing subtotal pancreatectomy for cancer. Cancer Nurs, 1991, 14(1): 27-34.

1. Lin QJ, Yang F, Jin C, et al. Current status and progress of pancreatic cancer in China. World J Gastroenterol, 2015, 21(26): 7988-8003.
2. Castellanos JA, Merchant NB. Intensity of follow-up after pancreatic cancer resection. Ann Surg Oncol, 2014, 21(3): 747-751.
3. Reddy SK, Tyler DS, Pappas TN, et al. Extended resection for pancreatic adenocarcinoma. Oncologist, 2007, 12(6): 654-663.
4. Casadei R, Monari F, Buscemi S, et al. Total pancreatectomy: indications, operative technique, and results: a single centre experience and review of literature. Updates Surg, 2010, 62(1): 41-46.
5. Glanemann M, Shi BM, Liang F, et al. Surgical strategies for treatment of malignant pancreatic tumors: extended, standard or local surgery?. World J Surg Oncol, 2008, 6: 123.
6. Suzuki S, Kajiyama H, Takemura A, et al. The clinical outcomes after total pancreatectomy. Dig Surg, 2017, 34(2): 142-150.
7. Gilliland TM, Villafane-Ferriol N, Shah KP, et al. Nutritional and metabolic derangements in pancreatic cancer and pancreatic resection. Nutrients, 2017, 9(3): E243.
8. Barreto SG, Windsor JA. Justifying vein resection with pancreatoduodenectomy. Lancet Oncol, 2016, 17(3): E118-E124.
9. Tong HX, Zhang L, Rong YF, et al. Long-term survival following total pancreatectomy and superior mesenteric-portal vein resection for pancreatic ductal adenocarcinoma: a case report. Oncol Lett, 2015, 9(1): 318-320.
10. Rockey EW. Total pancreatectomy for carcinoma: case report. Ann Surg, 1943, 118(4):603-611.
11. Zakaria HM, Stauffer JA, Raimondo M, et al. Total pancreatectomy: short- and long-term outcomes at a high-volume pancreas center. World J Gastrointest Surg, 2016, 8(9): 634-642.
12. Del Chiaro M, Rangelova E, Segersvard R, et al. Are there still indications for total pancreatectomy?. Updates Surg, 2016, 68(3): 257-263.
13. 丁如梅, 黄建业. 26 例全胰切除术病人的围术期护理. 全科护理, 2013(34): 3178-3180.
14. 谭亚非, 龚姝. 腹腔镜全胰切除术合并 2 型糖尿病患者的围手术期护理一例. 华西医学, 2017, 31(7): 1131-1132.
15. Bhayani NH, Enomoto LM, Miller JL, et al. Morbidity of total pancreatectomy with islet cell auto-transplantation compared to total pancreatectomy alone. HPB (Oxford), 2014, 16(6): 522-527.
16. Lightner AM, Glasgow RE, Jordan TH, et al. Pancreatic resection in the elderly. J Am Coll Surg, 2004, 198(5): 697-706.
17. Parks L, Routt M. Total pancreatectomy with islet cell transplantationfor the treatment of pancreatic cancer. Clin J Oncol Nurs, 2015, 19(4): 479-481.
18. Ulander K, Grahn G, Sundahl G, et al. Needs and care of patients undergoing subtotal pancreatectomy for cancer. Cancer Nurs, 1991, 14(1): 27-34.

West China Medical Journal

Risk factors of postoperative anxiety in patients with pancreatic cancer undergoing total pancreatectomy

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