Advances in clinical repair techniques for localized knee cartilage lesions_Chinese Journal of Reparative and Reconstructive Surgery

Authors：

TIAN Guangzhao ^1,2 , LI Runmeng ^1,2 , YANG Yongkang ^1,2 , NING Chao ¹ ,  GUO Quanyi ^1,2

1. Institute of Orthopedics, First Medical Center, General Hospital of Chinese PLA, Beijing, 100853, P. R. China;
2. School of Medicine, Nankai University, Tianjin, 300071, P. R. China;

Corresponding author：

GUO Quanyi, Email: doctorguo_301@163.com

Keywords：

Cartilage lesion; cartilage repair; clinical decision-making

DOI：

10.7507/1002-1892.202402056

Video：

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Objective To summarize the classic and latest treatment techniques for localized knee cartilage lesions in clinical practice and create a new comprehensive clinical decision-making process. Methods The advantages and limitations of various treatment methods for localized knee cartilage lesions were summarized by extensive review of relevant literature at home and abroad in recent years. Results Currently, there are various surgical methods for treating localized knee cartilage injuries in clinical practice, each with its own pros and cons. For patients with cartilage injuries less than 2 cm² and 2-4 cm² with bone loss are recommended to undergo osteochondral autograft (OAT) and osteochondral allograft (OCA) surgeries. For patients with cartilage injuries less than 2 cm² and 2-4 cm² without bone loss had treatment options including bone marrow-based techniques (micro-fracture and ogous matrix induced chondrogenesis), autologous chondrocyte implantation (ACI)/matrix-induced ACI, particulated juvenile allograft cartilage (PJAC), OAT, and OCA. For patients with cartilage injuries larger than 4 cm² with bone loss were recommended to undergo OCA. For patients with cartilage injuries larger than 4 cm² without bone loss, treatment options included ACI/matrix-induced ACI, OAT, and PJAC. Conclusion There are many treatment techniques available for localized knee cartilage lesions. Treatment strategy selection should be based on the size and location of the lesion, the extent of involvement of the subchondral bone, and the level of evidence supporting each technique in the literature.

Citation： TIAN Guangzhao, LI Runmeng, YANG Yongkang, NING Chao, GUO Quanyi. Advances in clinical repair techniques for localized knee cartilage lesions. Chinese Journal of Reparative and Reconstructive Surgery, 2024, 38(7): 889-895. doi: 10.7507/1002-1892.202402056 Copy

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Chinese Journal of Reparative and Reconstructive Surgery

Advances in clinical repair techniques for localized knee cartilage lesions

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