Progress on Prevention and Treatment of Postpneumonectomy Complications_Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Authors：

 WANGZhi-hai , SUNXiao-yan , GUOMing

Department of Cardiothoracic Surgery, PLA 174 th Clinical College of Anhui Medical University, Xiamen 361000, Fujian, P. R. China;

Corresponding author：

WANGZhi-hai, Email: xiahouhaiocean@sina.com

Keywords：

Pneumonectomy; Complication; Prevention; Treatment; Model lung

DOI：

10.7507/1007-4848.20150100

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Pneumonectomy is known as an effective treatment of lung cancer, lung tuberculosis, and damaged lung. But the incidences of complications and mortality are significantly higher in patients undergoing pneumonectomy than those undergoing lobectomy. The complication rate within 30 days after pneumonectomy is 11%-49% and the mortality is 3%-25%. Mortality of right pneumonectomy is triple that of left pneumonectomy. Postpneumonectomy complications include cardiopulmonary failure, bronchopleural fistula and postpneumonectomy syndrome. Besides the symptomatic treatment, which includes flushing drainage, plugging and operation, observation and prompt diagnosis are necessary for prevention. This review is focused on the prevention and treatment of complications after pneumonectomy.

Citation： WANGZhi-hai, SUNXiao-yan, GUOMing. Progress on Prevention and Treatment of Postpneumonectomy Complications. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2015, 22(4): 380-384. doi: 10.7507/1007-4848.20150100 Copy

1.	Klemperer J, Ginsberg RJ.Morbidity and mortality after pneumo-nectomy.Chest surg clin N Am, 1999, 9(3):515-525.
2.	Chandrashekhara SH, Bhalla AS, Sharma R, et al.Imaging in postpneumonectomy complications:a pictorial review.J Cancer Res Ther, 2011, 7(1):3-10.
3.	Harpole DH, Liptay MJ, DeCamp MM Jr, et al.Prospective analysis of pneumonectomy:risk factors for major morbidity and cardiac dysrhythmias.Ann Thorac Surg, 1996, 61(3):977-982.
4.	翁毅敏, 廖洪映, 李昀, 等.肺癌全肺切除术后心肺并发症的防治.中山大学学报(医学科学版), 2007, 28(z1):89-91.
5.	武艳.肺癌术后心律失常的危险因素分析.肿瘤学杂志, 2011, 17(12):917-919.
6.	Fan Y, Zhang AM, Xiao YB.Glucose-insulin-potassium therapy in adult patients undergoing cardiac surgery a meta-analysis.Eur J Cardiothorac Surg, 2011, 40(1):192-199.
7.	张竞, 王云喜, 初向阳, 等.肺癌全肺切除术后常见并发症临床分析.第三军医大学学报, 2012, 34(9):893-895.
8.	吴鲁卿, 张春芳, 张恒, 等.210例肺癌全肺切除临床分析.中南大学学报(医学版), 2008, 33(3):270-273.
9.	常涛, 张铸.肺癌患者术后院内肺部感染的相关因素分析.中国胸心血管外科临床杂志, 2013, 20(2):176-180.
10.	李学昌, 王伟, 尚立群, 等.高龄患者全肺切除术后心律失常发生.山东医药, 2013, 53(6):83-85.
11.	Reed CE, Dorman BH, Spinale FG.Assessment of right ventricular contractile performance after pulmonary resection.Ann Thorac Surg, 1993, 56(3):426-432.
12.	Swartz DE, Lachapelle K, Sampalis J, et al.Perioperative mortality after pneumonectomy:analysis of risk factors and review of the literature.Canadian J Surgery, 1997, 40(6):437-443.
13.	甄福喜, 赵欣, 张伟, 等.肺癌全肺切除术后早期右心功能不全的危险因素分析.临床肿瘤学杂志, 2013, 17(11):1006-1008.
14.	苏梓航, 叶穗晖, 杨正心.ACEI防治一侧全肺切除术后心功能不全的效果分析.广州医药, 2009, 40(1):16-19.
15.	陈波, 甘耐炎, 陈军, 等.全肺切除治疗肺癌72例临床分析.中国当代医药, 2011, 33(9):1176-1178.
16.	黄江远.老年肺癌患者行全肺切除术的围术期处理.中国当代医药, 2011, 18(12):176-179.
17.	丁嘉安, 姜格宁.肺切除术后近期死亡原因分析及对策.中华结核和呼吸杂志, 2000, 23(4):232-234.
18.	Koh WJ, Kim YH, Kwon OJ, et al.Surgical treatment of pulmonary diseases due to nontuberculous mycobacteria.J Korean Med Sci, 2008, 23(3):397-401.
19.	徐宝宁, 田大力.肺切除术后支气管胸膜瘘的防治体会.山东医药, 2013, 53(28):91-92.
20.	钱可宝, 张勇, 巫正伟, 等.肺切除术后并发支气管胸膜瘘的临床分析.昆明医学院学报, 2012, 33(3):36-38.
21.	Pop D, Nadeemy AS, Venissac N, et al.Bronchopleural fistula:the Damocles sword of all pneumonectomies.Interact Cardiovasc Thorac Surg, 2011, 13(1):107-108.
22.	张宝石, 于长海, 刘颖, 等.全肺切除术后支气管胸膜瘘的早期手术治疗.南方医科大学学报, 2010, 30(5):1147-1149.
23.	王涛, 朱余明, 高文, 等.肺切除术后支气管胸膜瘘的原因分析和处理.中国现代医学杂志, 2009, 19(15):2375-2377.
24.	Kilic A.Sciurba F, Luketich J, et al.Spontaneous bronchopleural-fistula following lung volume reduction surgery for emphysema.Interact Cardiovasc Thorac Surg, 2009, 8(4):442-443.
25.	Wolter A, Scholz T, Diedrichson J, et al.Bronchopleural fistula after pneumonectomy:interdisciplinary surgical closure by an ipsilateral pedicled latissimus dorsi flap supported by video-assisted thoracoscopy.J Plast Reconstr Aesthet Surg, 2013, 66(11):1600-1603.
26.	张志民, 辛国华, 侯继申, 等.肺切除术后支气管胸膜瘘的外科治疗.江苏医药, 2012, 38(6):725-726.
27.	Tayama K, Eriguchi N, Futamata Y, et al.Modified Dumon stent for the treatment of a bronchopleural fistula after pnumonectomy.Ann Thorac Surg, 2003, 75(1):290-292.
28.	Ishikawa K, Kato T, Aragaki M, et al.Endobronchial closure of a bronchopleural fistula using a fibrin glue-coated collagen patch and fibrin glue.Ann Thorac Cardiovasc Surg, 2013, 19(6):423-427.
29.	Wright CD, Wain JC, Mathisen DJ, et al.Postpneumonectomy bronchopleural fistula after sutured bronchial closure:Incidence, risk factors and management.J Thorac Cardiovasc Surg, 1996, 112(5):1367-1371.
30.	王斌, 李金东, 张兴义, 等.自体带蒂组织修补肺切除术后支气管胸膜瘘.中国现代药物应用, 2013, 7(14):68-69.
31.	张真铭, 王允.肺癌术后支气管胸膜瘘致死性大咯血经验.中国肺癌杂志, 2012, 15(1):39-43.
32.	罗清泉, 赵晓菁, 周允中, 等.肺癌全肺切除术后支气管胸膜瘘的原因分析和处理.中国癌症杂志, 2003, 13(4):373-375.
33.	Bédard EL, Uy K, Keshavjee S.Postpneumonectomy syndrome:a spectrum of clinical presentations.Ann Thorac Surg, 2007, 83(3):1185-1188.
34.	Lloyd MS, Wallis C, Muthialu N, et al.Treatment of postpneumo-nectomy syndrome with tissue expanders:the Great Ormond Street Hospital experience.J Plast Reconstr Aesthet Surg, 2014, 67(5):725-728.
35.	Valji AM, Maziak DE, Shamji FM, et al.Postpneumonectomy synd-rome recognition and management.Chest, 1998, 114(6):1766-1769.
36.	Choi L, LaQuaglia PM, Cordeiro GP.Prevention of postpneumonec-tomy syndrome in children with prophylactic tissue expander insertion.J Pediatr Surg, 2012, 47(7):1354-1357.
37.	Zahid I, Routledge T, Billè A, et al.What is the best treatment of postpneumonectomy empyema?Interact Cardiovasc Thorac Surg, 2011, 12(2):260-264.
38.	Sharifpour M, Bittner EA.Postpneumonectomy syndrome:a case of shifting priorities.Anesthesiology, 2014, 121(6):1334.
39.	Kreisel D, Krupnick AS, Huddleston CB.Outcomes and late complications after pulmonary resections in the pediatric population.Semin Thorac Cardiovasc Surg, 2004, 16(3):215-219.
40.	Saatvedt K, Hoel T, Westvik J, et al.Correction of postpneumonec-tomy syndrome in infants with saline-filled expandable prosthesis.Interact Cardiovasc Thorac Surg, 2011, 13(1):89-90.
41.	McRae MC, Detterbeck FC, Narayan D.Correction of postpneumo-nectomy syndrome using a custom implant.BMJ Case Rep, 2011.doi:10.1136/bcr.11.2010.3523.
42.	Podevin G, Larroquet M, Camby C, et al.Postpneumonectomy syndrome in children:advantages and long-term follow-up of expandable prosthesis.Pediatr Surg, 2001, 36(9):1425-1427.
43.	支修益, 卫生部临床路径审核专家委员会胸外科专家组.胸外科围手术期气道管理专家共识(2012年版).中国胸心血管外科临床杂志, 2013, 20(3):251-255.
44.	Jablonski S, Brocki M, Klejszmit P, et al.Repair of postpneumonec-tomy bronchopleural fistula using pedicled pericardial flap suppo-rted by fibrin glue.Int Wound J, 2013 Apr 5.doi:10.1111/iwj.12072.
45.	Spartalis E, Tomos P, Konofaos P, et al.The effect of autologous platelet-rich plasma on bronchial stump tissue granulation after pneumonectomy:experimental study.ISRN Surg, 2013:864350.
46.	Shen RK, Wain CJ, Wright DC, et al.Postpneumonectomy syndrome:surgical management and long-term results.J Thorac Cardiovasc Surg, 2008, 135(6):1210-1216.

1. Klemperer J, Ginsberg RJ.Morbidity and mortality after pneumo-nectomy.Chest surg clin N Am, 1999, 9(3):515-525.
2. Chandrashekhara SH, Bhalla AS, Sharma R, et al.Imaging in postpneumonectomy complications:a pictorial review.J Cancer Res Ther, 2011, 7(1):3-10.
3. Harpole DH, Liptay MJ, DeCamp MM Jr, et al.Prospective analysis of pneumonectomy:risk factors for major morbidity and cardiac dysrhythmias.Ann Thorac Surg, 1996, 61(3):977-982.
4. 翁毅敏, 廖洪映, 李昀, 等.肺癌全肺切除术后心肺并发症的防治.中山大学学报(医学科学版), 2007, 28(z1):89-91.
5. 武艳.肺癌术后心律失常的危险因素分析.肿瘤学杂志, 2011, 17(12):917-919.
6. Fan Y, Zhang AM, Xiao YB.Glucose-insulin-potassium therapy in adult patients undergoing cardiac surgery a meta-analysis.Eur J Cardiothorac Surg, 2011, 40(1):192-199.
7. 张竞, 王云喜, 初向阳, 等.肺癌全肺切除术后常见并发症临床分析.第三军医大学学报, 2012, 34(9):893-895.
8. 吴鲁卿, 张春芳, 张恒, 等.210例肺癌全肺切除临床分析.中南大学学报(医学版), 2008, 33(3):270-273.
9. 常涛, 张铸.肺癌患者术后院内肺部感染的相关因素分析.中国胸心血管外科临床杂志, 2013, 20(2):176-180.
10. 李学昌, 王伟, 尚立群, 等.高龄患者全肺切除术后心律失常发生.山东医药, 2013, 53(6):83-85.
11. Reed CE, Dorman BH, Spinale FG.Assessment of right ventricular contractile performance after pulmonary resection.Ann Thorac Surg, 1993, 56(3):426-432.
12. Swartz DE, Lachapelle K, Sampalis J, et al.Perioperative mortality after pneumonectomy:analysis of risk factors and review of the literature.Canadian J Surgery, 1997, 40(6):437-443.
13. 甄福喜, 赵欣, 张伟, 等.肺癌全肺切除术后早期右心功能不全的危险因素分析.临床肿瘤学杂志, 2013, 17(11):1006-1008.
14. 苏梓航, 叶穗晖, 杨正心.ACEI防治一侧全肺切除术后心功能不全的效果分析.广州医药, 2009, 40(1):16-19.
15. 陈波, 甘耐炎, 陈军, 等.全肺切除治疗肺癌72例临床分析.中国当代医药, 2011, 33(9):1176-1178.
16. 黄江远.老年肺癌患者行全肺切除术的围术期处理.中国当代医药, 2011, 18(12):176-179.
17. 丁嘉安, 姜格宁.肺切除术后近期死亡原因分析及对策.中华结核和呼吸杂志, 2000, 23(4):232-234.
18. Koh WJ, Kim YH, Kwon OJ, et al.Surgical treatment of pulmonary diseases due to nontuberculous mycobacteria.J Korean Med Sci, 2008, 23(3):397-401.
19. 徐宝宁, 田大力.肺切除术后支气管胸膜瘘的防治体会.山东医药, 2013, 53(28):91-92.
20. 钱可宝, 张勇, 巫正伟, 等.肺切除术后并发支气管胸膜瘘的临床分析.昆明医学院学报, 2012, 33(3):36-38.
21. Pop D, Nadeemy AS, Venissac N, et al.Bronchopleural fistula:the Damocles sword of all pneumonectomies.Interact Cardiovasc Thorac Surg, 2011, 13(1):107-108.
22. 张宝石, 于长海, 刘颖, 等.全肺切除术后支气管胸膜瘘的早期手术治疗.南方医科大学学报, 2010, 30(5):1147-1149.
23. 王涛, 朱余明, 高文, 等.肺切除术后支气管胸膜瘘的原因分析和处理.中国现代医学杂志, 2009, 19(15):2375-2377.
24. Kilic A.Sciurba F, Luketich J, et al.Spontaneous bronchopleural-fistula following lung volume reduction surgery for emphysema.Interact Cardiovasc Thorac Surg, 2009, 8(4):442-443.
25. Wolter A, Scholz T, Diedrichson J, et al.Bronchopleural fistula after pneumonectomy:interdisciplinary surgical closure by an ipsilateral pedicled latissimus dorsi flap supported by video-assisted thoracoscopy.J Plast Reconstr Aesthet Surg, 2013, 66(11):1600-1603.
26. 张志民, 辛国华, 侯继申, 等.肺切除术后支气管胸膜瘘的外科治疗.江苏医药, 2012, 38(6):725-726.
27. Tayama K, Eriguchi N, Futamata Y, et al.Modified Dumon stent for the treatment of a bronchopleural fistula after pnumonectomy.Ann Thorac Surg, 2003, 75(1):290-292.
28. Ishikawa K, Kato T, Aragaki M, et al.Endobronchial closure of a bronchopleural fistula using a fibrin glue-coated collagen patch and fibrin glue.Ann Thorac Cardiovasc Surg, 2013, 19(6):423-427.
29. Wright CD, Wain JC, Mathisen DJ, et al.Postpneumonectomy bronchopleural fistula after sutured bronchial closure:Incidence, risk factors and management.J Thorac Cardiovasc Surg, 1996, 112(5):1367-1371.
30. 王斌, 李金东, 张兴义, 等.自体带蒂组织修补肺切除术后支气管胸膜瘘.中国现代药物应用, 2013, 7(14):68-69.
31. 张真铭, 王允.肺癌术后支气管胸膜瘘致死性大咯血经验.中国肺癌杂志, 2012, 15(1):39-43.
32. 罗清泉, 赵晓菁, 周允中, 等.肺癌全肺切除术后支气管胸膜瘘的原因分析和处理.中国癌症杂志, 2003, 13(4):373-375.
33. Bédard EL, Uy K, Keshavjee S.Postpneumonectomy syndrome:a spectrum of clinical presentations.Ann Thorac Surg, 2007, 83(3):1185-1188.
34. Lloyd MS, Wallis C, Muthialu N, et al.Treatment of postpneumo-nectomy syndrome with tissue expanders:the Great Ormond Street Hospital experience.J Plast Reconstr Aesthet Surg, 2014, 67(5):725-728.
35. Valji AM, Maziak DE, Shamji FM, et al.Postpneumonectomy synd-rome recognition and management.Chest, 1998, 114(6):1766-1769.
36. Choi L, LaQuaglia PM, Cordeiro GP.Prevention of postpneumonec-tomy syndrome in children with prophylactic tissue expander insertion.J Pediatr Surg, 2012, 47(7):1354-1357.
37. Zahid I, Routledge T, Billè A, et al.What is the best treatment of postpneumonectomy empyema?Interact Cardiovasc Thorac Surg, 2011, 12(2):260-264.
38. Sharifpour M, Bittner EA.Postpneumonectomy syndrome:a case of shifting priorities.Anesthesiology, 2014, 121(6):1334.
39. Kreisel D, Krupnick AS, Huddleston CB.Outcomes and late complications after pulmonary resections in the pediatric population.Semin Thorac Cardiovasc Surg, 2004, 16(3):215-219.
40. Saatvedt K, Hoel T, Westvik J, et al.Correction of postpneumonec-tomy syndrome in infants with saline-filled expandable prosthesis.Interact Cardiovasc Thorac Surg, 2011, 13(1):89-90.
41. McRae MC, Detterbeck FC, Narayan D.Correction of postpneumo-nectomy syndrome using a custom implant.BMJ Case Rep, 2011.doi:10.1136/bcr.11.2010.3523.
42. Podevin G, Larroquet M, Camby C, et al.Postpneumonectomy syndrome in children:advantages and long-term follow-up of expandable prosthesis.Pediatr Surg, 2001, 36(9):1425-1427.
43. 支修益, 卫生部临床路径审核专家委员会胸外科专家组.胸外科围手术期气道管理专家共识(2012年版).中国胸心血管外科临床杂志, 2013, 20(3):251-255.
44. Jablonski S, Brocki M, Klejszmit P, et al.Repair of postpneumonec-tomy bronchopleural fistula using pedicled pericardial flap suppo-rted by fibrin glue.Int Wound J, 2013 Apr 5.doi:10.1111/iwj.12072.
45. Spartalis E, Tomos P, Konofaos P, et al.The effect of autologous platelet-rich plasma on bronchial stump tissue granulation after pneumonectomy:experimental study.ISRN Surg, 2013:864350.
46. Shen RK, Wain CJ, Wright DC, et al.Postpneumonectomy syndrome:surgical management and long-term results.J Thorac Cardiovasc Surg, 2008, 135(6):1210-1216.

Previous Article
Bone Marrow Mesenchymal Stem Cells for Treatment of Seawater Drowning Induced Acute Lung Injury
Next Article
胸腔镜辅助下主动脉瓣置换术临床分析

Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Progress on Prevention and Treatment of Postpneumonectomy Complications

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content