Computational Evaluation of the Fluid Dynamics of a Disk Blood Pump_Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Authors：

HANLu , WANGWei , LIUJin-long , YUXiao-qing ,  CAIJi-ming

Department of Cardiovascular and Thoracic Surgery, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, P.R.China;

Corresponding author：

CAIJi-ming, Email: rosemarycjm@163.com

Keywords：

Vetricular assist device; Blood pump; Thrombosis and hemolysis; Computational fluid dynamics

DOI：

10.7507/1007-4848.20160088

Video：

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Abstract Full text Figures/Tables Video References Cited by

Objective To optimize the hemodynamics of a disk blood pump in children. Method We used the computational fluid dynamics technology to simulate the flow in a pediatric blood pump numerically, and finally analyzed the results for deep study about the thrombosis and hemolysis produced in it, to improve the design according to the results of the flow field analysis. Results We calculated results between the flow rate and the pressure elevation at different rotational speed: 2 500 rpm, 3 000 rpm, and 4 000 rpm, respectively. Under each rotational speed, it was selected five different discharge outlet boundary conditions. The simulation results conformed to the experimental data. The increased pressure of the blood pump was effective. But the phenomenon of flow separation was increased the at blade surface in the low speed region. The maximum wall shear stress was maintained within 100 Pa. Conclusion The design of disc blood pump has a good fluid dynamic performance. And the flow line is fluent, the probability of thrombosis and hemolysis occurred is in the range of control. But the phenomenon of flow separation is appeared. There is a room to improve.

Citation： HANLu, WANGWei, LIUJin-long, YUXiao-qing, CAIJi-ming. Computational Evaluation of the Fluid Dynamics of a Disk Blood Pump. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2016, 23(4): 380-385. doi: 10.7507/1007-4848.20160088 Copy

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14.	Takao H, Murayama Y, Otsuka S, et al. Hemodynamic differences between unruptured and ruptured intracranial aneurysms during observation. Stroke, 2012, 43(5): 1436-1439.
15.	Chandra S, Raut SS, Jana A, et al. Fluid-structure interaction modelling of abdominal aortic aneurysms: the impact of patient-specific inflow conditions and fluid/solid coupling. J Biomechan Engin, 2013, 135(8): 81001.
16.	Reymond P, Crosetto P, Deparis S, et al. Physiological simulation of blood flow in the aorta: Comparison of hemodynamic indices as predicted by 3-D FSI, 3-D rigid wall and 1-D models. Med Eng Phys, 2013, 35(6): 784-791.
17.	Inci G, Sorguven E. Effect of LVAD outlet graft anastomosis angle on the aortic valve, wall, and flow. ASAIO J, 2012, 58(4): 373-381.

1. Goubergrits L, Affeld K. Numerical estimation of blood damage in artificial organs. Artif Organs, 2004, 28(5): 499-507.
2. Arvand A, Hormes M, Reul H. A validated computational fluid dynamics model to estimate hemolysis in a rotary blood pump. Artif Organs, 2005, 29(7): 531-540.
3. Heilmann C, Geisen U, Benk C, et al. Hemolysis in patients with ventricular assist devices: major differences between systems. Eur J Cardiothorac Surg, 2009, 36(3): 580-584.
4. Giersiepen M, Wurzinger LJ, Opitz R, et al. Estimation of shear stress-related blood damage in heart valve prostheses--in vitro comparison of 25 aortic valves. Int J Artif Organs, 1990, 13(5): 300.
5. Watanabe N, Masuda T, Iida T, et al. Quantification of the secondary flow in a radial coupled centrifugal blood pump based on particle tracking velocimetry. Artif Organs, 2005, 29(1): 26-35.
6. Rose EA, Gelijins AC, Moskowitz AJ, et al. Long-term mechanical left ventricular assistance for end-stage heart failure. N Engl J Med, 2001, 345(20): 1435-1443.
7. Takatani S, Hoshi H, Tajima K, et al. Feasibility of a miniature centrifugal rotary blood pump for low-flow circulation in children and infants. ASAIO J, 2005, 51(5): 557-562.
8. Duncan BW, Dudzinski DT, Noecker AM, et al. The pedipump: development status of a new pediatric ventricular assist device. ASAIO J, 2005, 51(5): 536-539.
9. Menon PG, Antaki JF, Undar A, et al. Aortic outflow cannula tip design and orientation impacts cerebral perfusion during pediatric cardiopulmonary bypass procedures. Ann Biomed Eng, 2013, 41 (12): 2588-2602.
10. Kaufmann TA, Schlanstein P, Moritz A, et al. Development of a hemodynamically optimized outflow cannula for cardiopulmonary bypass. Artif Organs, 2014, 38(11): 972-978.
11. Neidlin M, Jansen S, Moritz AU, et al. Design modifications and computational fluid dynamic analysis of an outflow cannula for cardiopulmonary bypass. Ann Biomed Eng, 2014, 42(10): 1-10.
12. Avrahami I, Dilmoney B, Azuri A, et al. Investigation of risks for cerebral embolism associated with the hemodynamics of cardiopulmonary bypass cannula: a numerical model. Artif Organs, 2013, 37(10): 857-865.
13. Karmonik C, Partovi S, Loebe M, et al. Influence of LVAD cannula outflow tract location on hemodynamics in the ascending aorta: a patient-specific computational fluid dynamics approach. ASAIO J, 2012, 58(6): 562-567.
14. Takao H, Murayama Y, Otsuka S, et al. Hemodynamic differences between unruptured and ruptured intracranial aneurysms during observation. Stroke, 2012, 43(5): 1436-1439.
15. Chandra S, Raut SS, Jana A, et al. Fluid-structure interaction modelling of abdominal aortic aneurysms: the impact of patient-specific inflow conditions and fluid/solid coupling. J Biomechan Engin, 2013, 135(8): 81001.
16. Reymond P, Crosetto P, Deparis S, et al. Physiological simulation of blood flow in the aorta: Comparison of hemodynamic indices as predicted by 3-D FSI, 3-D rigid wall and 1-D models. Med Eng Phys, 2013, 35(6): 784-791.
17. Inci G, Sorguven E. Effect of LVAD outlet graft anastomosis angle on the aortic valve, wall, and flow. ASAIO J, 2012, 58(4): 373-381.

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Computational Evaluation of the Fluid Dynamics of a Disk Blood Pump

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