Application and progress of extracorporeal membrane oxygenation in general thoracic surgery_Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Authors：

CHENG Shizhao ,  LU Xike

Department of Thoracic Surgery, Tianjin Chest Hospital, Tianjin, 300222, P. R. China;

Corresponding author：

LU Xike, Email: luxike@yahoo.com

Keywords：

Extracorporeal membrane oxygenation; general thoracic surgery; lung transplantation; heart and lung support; review

DOI：

10.7507/1007-4848.202101080

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Extracorporeal membrane oxygenation (ECMO), as an extracorporeal life support technology, can provide respiratory support and hemodynamic support according to different modes. The significant advantages of ECMO in the treatment of acute respiratory distress syndrome and the development of its oxygenator, pump, and heparin-coated circuits have promoted its application and exploration in thoracic surgery. ECMO can be used during the perioperative period of lung transplantation and can be applied for patients who cannot maintain one-lung ventilation, or have a high risk of anesthesia, or undergo complex thoracic surgery involving trachea, carina, mediastinum and esophagus. This article will review the application and progress of ECMO in general thoracic surgery.

Citation： CHENG Shizhao, LU Xike. Application and progress of extracorporeal membrane oxygenation in general thoracic surgery. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2022, 29(3): 384-389. doi: 10.7507/1007-4848.202101080 Copy

1.	Combes A, Schmidt M, Hodgson CL, et al. Extracorporeal life support for adults with acute respiratory distress syndrome. Intensive Care Med, 2020, 46(12): 2464-2476.
2.	Peek GJ, Mugford M, Tiruvoipati R, et al. Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): A multicentre randomised controlled trial. Lancet, 2009, 374(9698): 1351-1363.
3.	Combes A, Hajage D, Capellier G, et al. Extracorporeal membrane oxygenation for severe acute respiratory distress syndrome. N Engl J Med, 2018, 378(21): 1965-1975.
4.	McRae K, de Perrot M. Principles and indications of extracorporeal life support in general thoracic surgery. J Thorac Dis, 2018, 10(Suppl 8): S931-S946.
5.	Hoetzenecker K, Klepetko W, Keshavjee S, et al. Extracorporeal support in airway surgery. J Thorac Dis, 2017, 9(7): 2108-2117.
6.	Rinieri P, Peillon C, Bessou JP, et al. National review of use of extracorporeal membrane oxygenation as respiratory support in thoracic surgery excluding lung transplantation. Eur J Cardiothorac Surg, 2015, 47(1): 87-94.
7.	Malpas G, Hung O, Gilchrist A, et al. The use of extracorporeal membrane oxygenation in the anticipated difficult airway: A case report and systematic review. Can J Anaesth, 2018, 65(6): 685-697.
8.	Johannesen S, Deb SJ. Intraoperative extracorporeal membrane oxygenation in thoracic surgery. Ann Thorac Surg, 2020, 110(3): e157-e159.
9.	Lang G, Ghanim B, Hötzenecker K, et al. Extracorporeal membrane oxygenation support for complex tracheo-bronchial procedures. Eur J Cardiothorac Surg, 2015, 47(2): 250-255.
10.	Koryllos A, Lopez-Pastorini A, Galetin T, et al. Use of extracorporeal membrane oxygenation for major cardiopulmonary resections. Thorac Cardiovasc Surg, 2021, 69(3): 231-239.
11.	Redwan B, Ziegeler S, Freermann S, et al. Intraoperative veno-venous extracorporeal lung support in thoracic surgery: A single-centre experience. Interact Cardiovasc Thorac Surg, 2015, 21(6): 766-772.
12.	Heward E, Hayes T, Evison M, et al. Extracorporeal membrane oxygenation assisted segmentectomy for metachronous lung cancer after pneumonectomy. Ann Thorac Surg, 2016, 102(3): e187-e189.
13.	Gillon SA, Toufektzian L, Harrison-Phipps K, et al. Perioperative extracorporeal membrane oxygenation to facilitate lung resection after contralateral pneumonectomy. Ann Thorac Surg, 2016, 101(3): e71-e73.
14.	Oey IF, Peek GJ, Firmin RK, et al. Post-pneumonectomy video-assisted thoracoscopic bullectomy using extra-corporeal membrane oxygenation. Eur J Cardiothorac Surg, 2001, 20(4): 874-876.
15.	You B, Zhao Y, Hou S, et al. Lung volume reduction surgery in hypercapnic patients: A single-center experience from China. J Thorac Dis, 2018, 10(Suppl 23): S2698-S2703.
16.	Akil A, Ziegeler S, Reichelt J, et al. Veno-venous extracorporeal lung support as a bridge to or through lung volume reduction surgery in patients with severe hypercapnia. ASAIO J, 2020, 66(8): 952-959.
17.	Felten ML, Michel-Cherqui M, Puyo P, et al. Extracorporeal membrane oxygenation use for mediastinal tumor resection. Ann Thorac Surg, 2010, 89(3): 1012.
18.	Raza HA, Nokes BT, Jaroszewski D, et al. VV-ECMO for surgical cure of a critical central airway obstruction. Respir Med Case Rep, 2019, 28: 100890.
19.	Kodia K, Liu Y, Ghodsizad A, et al. Use of venovenous extracorporeal membrane oxygenation for resection of a large paratracheal mass causing critical tracheal stenosis: A case report. J Card Surg, 2021, 36(1): 367-370.
20.	Zhang S, Tan D, Wu W, et al. Extracorporeal membrane oxygenation (ECMO) assisted mediastinal tumor resection and superior vena cava replacement are safe and feasible. Thorac Cancer, 2019, 10(9): 1846-1851.
21.	Schiff JH, Köninger J, Teschner J, et al. Veno-venous extracorporeal membrane oxygenation (ECMO) support during anaesthesia for oesophagectomy. Anaesthesia, 2013, 68(5): 527-530.
22.	Xu HC, Ye P, Bao FC, et al. ECMO-assisted esophagectomy after left pneumonectomy. Int J Artif Organs, 2013, 36(4): 259-262.
23.	Machuca TN, Cypel M, Keshavjee S. Cardiopulmonary bypass and extracorporeal life support for emergent intraoperative thoracic situations. Thorac Surg Clin, 2015, 25(3): 325-334.
24.	Martin AK, Jayaraman AL, Nabzdyk CG, et al. Extracorporeal membrane oxygenation in lung transplantation: Analysis of techniques and outcomes. J Cardiothorac Vasc Anesth, 2021, 35(2): 644-661.
25.	Hayanga JWA, Chan EG, Musgrove K, et al. Extracorporeal membrane oxygenation in the perioperative care of the lung transplant patient. Semin Cardiothorac Vasc Anesth, 2020, 24(1): 45-53.
26.	Tsiouris A, Budev MM, Yun JJ. Extracorporeal membrane oxygenation as a bridge to lung transplantation in the United States: A multicenter survey. ASAIO J, Sep/Oct 2018, 64(5): 689-693.
27.	Hayanga JWA, Hayanga HK, Holmes SD, et al. Mechanical ventilation and extracorporeal membrane oxygenation as a bridge to lung transplantation: Closing the gap. J Heart Lung Transplant, 2019, 38(10): 1104-1111.
28.	Lindholm JA. Ambulatory veno-venous extracorporeal membrane oxygenation. J Thorac Dis, 2018, 10(Suppl 5): S670-S673.
29.	Fuehner T, Kuehn C, Hadem J, et al. Extracorporeal membrane oxygenation in awake patients as bridge to lung transplantation. Am J Respir Crit Care Med, 2012, 185(7): 763-768.
30.	Nosotti M, Rosso L, Tosi D, et al. Extracorporeal membrane oxygenation with spontaneous breathing as a bridge to lung transplantation. Interact Cardiovasc Thorac Surg, 2013, 16(1): 55-59.
31.	Funamoto M, Moonsamy P, Ong CS, et al. "Awake" extracorporeal membrane oxygenation as a bridge to lung transplant. J Heart Lung Transplant, 2020, 39(4s): S218.
32.	Machuca TN, Collaud S, Mercier O, et al. Outcomes of intraoperative extracorporeal membrane oxygenation versus cardiopulmonary bypass for lung transplantation. J Thorac Cardiovasc Surg, 2015, 149(4): 1152-1157.
33.	Magouliotis DE, Tasiopoulou VS, Svokos AA, et al. Extracorporeal membrane oxygenation versus cardiopulmonary bypass during lung transplantation: A meta-analysis. Gen Thorac Cardiovasc Surg, 2018, 66(1): 38-47.
34.	Ius F, Sommer W, Tudorache I, et al. Five-year experience with intraoperative extracorporeal membrane oxygenation in lung transplantation: Indications and midterm results. J Heart Lung Transplant, 2016, 35(1): 49-58.
35.	Hoetzenecker K, Schwarz S, Muckenhuber M, et al. Intraoperative extracorporeal membrane oxygenation and the possibility of postoperative prolongation improve survival in bilateral lung transplantation. J Thorac Cardiovasc Surg, 2018, 155(5): 2193-2206.
36.	Van Raemdonck D, Hartwig MG, Hertz MI, et al. Report of the ISHLT Working Group on primary lung graft dysfunction Part Ⅳ: Prevention and treatment: A 2016 Consensus Group statement of the International Society for Heart and Lung Transplantation. J Heart Lung Transplant, 2017, 36(10): 1121-1136.
37.	Bermudez CA, Adusumilli PS, McCurry KR, et al. Extracorporeal membrane oxygenation for primary graft dysfunction after lung transplantation: Long-term survival. Ann Thorac Surg, 2009, 87(3): 854-860.
38.	Hartwig MG, Walczak R, Lin SS, et al. Improved survival but marginal allograft function in patients treated with extracorporeal membrane oxygenation after lung transplantation. Ann Thorac Surg, 2012, 93(2): 366-371.
39.	Jacobs JV, Hooft NM, Robinson BR, et al. The use of extracorporeal membrane oxygenation in blunt thoracic trauma: A study of the Extracorporeal Life Support Organization database. J Trauma Acute Care Surg, 2015, 79(6): 1049-1053.
40.	Mulder L, Keelan S, Kang D, et al. Early use of extracorporeal membrane oxygenation after penetrating thoracic trauma. Am Surg, 2018, 84(9): e416-e417.
41.	Sugiyama T, Ishida T, Yokoyama H, et al. The use of veno-venous extracorporeal membrane oxygenation for massive hemoptysis following a traumatic lung injury: A case report. Acute Med Surg, 2020, 7(1): e492.
42.	Zhang BY, Chen XC, You Y, et al. Massive pulmonary haemorrhage due to severe trauma treated with repeated alveolar lavage combined with extracorporeal membrane oxygenation: A case report. World J Clin Cases, 2020, 8(18): 4245-4251.
43.	Thiagarajan RR, Barbaro RP, Rycus PT, et al. Extracorporeal Life Support Organization Registry International Report 2016. ASAIO J, 2017, 63(1): 60-67.
44.	Mazzeffi M, Greenwood J, Tanaka K, et al. Bleeding, transfusion, and mortality on extracorporeal life support: ECLS Working Group on Thrombosis and Hemostasis. Ann Thorac Surg, 2016, 101(2): 682-689.
45.	Sklar MC, Sy E, Lequier L, et al. Anticoagulation practices during venovenous extracorporeal membrane oxygenation for respiratory failure. A systematic review. Ann Am Thorac Soc, 2016, 13(12): 2242-2250.

1. Combes A, Schmidt M, Hodgson CL, et al. Extracorporeal life support for adults with acute respiratory distress syndrome. Intensive Care Med, 2020, 46(12): 2464-2476.
2. Peek GJ, Mugford M, Tiruvoipati R, et al. Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): A multicentre randomised controlled trial. Lancet, 2009, 374(9698): 1351-1363.
3. Combes A, Hajage D, Capellier G, et al. Extracorporeal membrane oxygenation for severe acute respiratory distress syndrome. N Engl J Med, 2018, 378(21): 1965-1975.
4. McRae K, de Perrot M. Principles and indications of extracorporeal life support in general thoracic surgery. J Thorac Dis, 2018, 10(Suppl 8): S931-S946.
5. Hoetzenecker K, Klepetko W, Keshavjee S, et al. Extracorporeal support in airway surgery. J Thorac Dis, 2017, 9(7): 2108-2117.
6. Rinieri P, Peillon C, Bessou JP, et al. National review of use of extracorporeal membrane oxygenation as respiratory support in thoracic surgery excluding lung transplantation. Eur J Cardiothorac Surg, 2015, 47(1): 87-94.
7. Malpas G, Hung O, Gilchrist A, et al. The use of extracorporeal membrane oxygenation in the anticipated difficult airway: A case report and systematic review. Can J Anaesth, 2018, 65(6): 685-697.
8. Johannesen S, Deb SJ. Intraoperative extracorporeal membrane oxygenation in thoracic surgery. Ann Thorac Surg, 2020, 110(3): e157-e159.
9. Lang G, Ghanim B, Hötzenecker K, et al. Extracorporeal membrane oxygenation support for complex tracheo-bronchial procedures. Eur J Cardiothorac Surg, 2015, 47(2): 250-255.
10. Koryllos A, Lopez-Pastorini A, Galetin T, et al. Use of extracorporeal membrane oxygenation for major cardiopulmonary resections. Thorac Cardiovasc Surg, 2021, 69(3): 231-239.
11. Redwan B, Ziegeler S, Freermann S, et al. Intraoperative veno-venous extracorporeal lung support in thoracic surgery: A single-centre experience. Interact Cardiovasc Thorac Surg, 2015, 21(6): 766-772.
12. Heward E, Hayes T, Evison M, et al. Extracorporeal membrane oxygenation assisted segmentectomy for metachronous lung cancer after pneumonectomy. Ann Thorac Surg, 2016, 102(3): e187-e189.
13. Gillon SA, Toufektzian L, Harrison-Phipps K, et al. Perioperative extracorporeal membrane oxygenation to facilitate lung resection after contralateral pneumonectomy. Ann Thorac Surg, 2016, 101(3): e71-e73.
14. Oey IF, Peek GJ, Firmin RK, et al. Post-pneumonectomy video-assisted thoracoscopic bullectomy using extra-corporeal membrane oxygenation. Eur J Cardiothorac Surg, 2001, 20(4): 874-876.
15. You B, Zhao Y, Hou S, et al. Lung volume reduction surgery in hypercapnic patients: A single-center experience from China. J Thorac Dis, 2018, 10(Suppl 23): S2698-S2703.
16. Akil A, Ziegeler S, Reichelt J, et al. Veno-venous extracorporeal lung support as a bridge to or through lung volume reduction surgery in patients with severe hypercapnia. ASAIO J, 2020, 66(8): 952-959.
17. Felten ML, Michel-Cherqui M, Puyo P, et al. Extracorporeal membrane oxygenation use for mediastinal tumor resection. Ann Thorac Surg, 2010, 89(3): 1012.
18. Raza HA, Nokes BT, Jaroszewski D, et al. VV-ECMO for surgical cure of a critical central airway obstruction. Respir Med Case Rep, 2019, 28: 100890.
19. Kodia K, Liu Y, Ghodsizad A, et al. Use of venovenous extracorporeal membrane oxygenation for resection of a large paratracheal mass causing critical tracheal stenosis: A case report. J Card Surg, 2021, 36(1): 367-370.
20. Zhang S, Tan D, Wu W, et al. Extracorporeal membrane oxygenation (ECMO) assisted mediastinal tumor resection and superior vena cava replacement are safe and feasible. Thorac Cancer, 2019, 10(9): 1846-1851.
21. Schiff JH, Köninger J, Teschner J, et al. Veno-venous extracorporeal membrane oxygenation (ECMO) support during anaesthesia for oesophagectomy. Anaesthesia, 2013, 68(5): 527-530.
22. Xu HC, Ye P, Bao FC, et al. ECMO-assisted esophagectomy after left pneumonectomy. Int J Artif Organs, 2013, 36(4): 259-262.
23. Machuca TN, Cypel M, Keshavjee S. Cardiopulmonary bypass and extracorporeal life support for emergent intraoperative thoracic situations. Thorac Surg Clin, 2015, 25(3): 325-334.
24. Martin AK, Jayaraman AL, Nabzdyk CG, et al. Extracorporeal membrane oxygenation in lung transplantation: Analysis of techniques and outcomes. J Cardiothorac Vasc Anesth, 2021, 35(2): 644-661.
25. Hayanga JWA, Chan EG, Musgrove K, et al. Extracorporeal membrane oxygenation in the perioperative care of the lung transplant patient. Semin Cardiothorac Vasc Anesth, 2020, 24(1): 45-53.
26. Tsiouris A, Budev MM, Yun JJ. Extracorporeal membrane oxygenation as a bridge to lung transplantation in the United States: A multicenter survey. ASAIO J, Sep/Oct 2018, 64(5): 689-693.
27. Hayanga JWA, Hayanga HK, Holmes SD, et al. Mechanical ventilation and extracorporeal membrane oxygenation as a bridge to lung transplantation: Closing the gap. J Heart Lung Transplant, 2019, 38(10): 1104-1111.
28. Lindholm JA. Ambulatory veno-venous extracorporeal membrane oxygenation. J Thorac Dis, 2018, 10(Suppl 5): S670-S673.
29. Fuehner T, Kuehn C, Hadem J, et al. Extracorporeal membrane oxygenation in awake patients as bridge to lung transplantation. Am J Respir Crit Care Med, 2012, 185(7): 763-768.
30. Nosotti M, Rosso L, Tosi D, et al. Extracorporeal membrane oxygenation with spontaneous breathing as a bridge to lung transplantation. Interact Cardiovasc Thorac Surg, 2013, 16(1): 55-59.
31. Funamoto M, Moonsamy P, Ong CS, et al. "Awake" extracorporeal membrane oxygenation as a bridge to lung transplant. J Heart Lung Transplant, 2020, 39(4s): S218.
32. Machuca TN, Collaud S, Mercier O, et al. Outcomes of intraoperative extracorporeal membrane oxygenation versus cardiopulmonary bypass for lung transplantation. J Thorac Cardiovasc Surg, 2015, 149(4): 1152-1157.
33. Magouliotis DE, Tasiopoulou VS, Svokos AA, et al. Extracorporeal membrane oxygenation versus cardiopulmonary bypass during lung transplantation: A meta-analysis. Gen Thorac Cardiovasc Surg, 2018, 66(1): 38-47.
34. Ius F, Sommer W, Tudorache I, et al. Five-year experience with intraoperative extracorporeal membrane oxygenation in lung transplantation: Indications and midterm results. J Heart Lung Transplant, 2016, 35(1): 49-58.
35. Hoetzenecker K, Schwarz S, Muckenhuber M, et al. Intraoperative extracorporeal membrane oxygenation and the possibility of postoperative prolongation improve survival in bilateral lung transplantation. J Thorac Cardiovasc Surg, 2018, 155(5): 2193-2206.
36. Van Raemdonck D, Hartwig MG, Hertz MI, et al. Report of the ISHLT Working Group on primary lung graft dysfunction Part Ⅳ: Prevention and treatment: A 2016 Consensus Group statement of the International Society for Heart and Lung Transplantation. J Heart Lung Transplant, 2017, 36(10): 1121-1136.
37. Bermudez CA, Adusumilli PS, McCurry KR, et al. Extracorporeal membrane oxygenation for primary graft dysfunction after lung transplantation: Long-term survival. Ann Thorac Surg, 2009, 87(3): 854-860.
38. Hartwig MG, Walczak R, Lin SS, et al. Improved survival but marginal allograft function in patients treated with extracorporeal membrane oxygenation after lung transplantation. Ann Thorac Surg, 2012, 93(2): 366-371.
39. Jacobs JV, Hooft NM, Robinson BR, et al. The use of extracorporeal membrane oxygenation in blunt thoracic trauma: A study of the Extracorporeal Life Support Organization database. J Trauma Acute Care Surg, 2015, 79(6): 1049-1053.
40. Mulder L, Keelan S, Kang D, et al. Early use of extracorporeal membrane oxygenation after penetrating thoracic trauma. Am Surg, 2018, 84(9): e416-e417.
41. Sugiyama T, Ishida T, Yokoyama H, et al. The use of veno-venous extracorporeal membrane oxygenation for massive hemoptysis following a traumatic lung injury: A case report. Acute Med Surg, 2020, 7(1): e492.
42. Zhang BY, Chen XC, You Y, et al. Massive pulmonary haemorrhage due to severe trauma treated with repeated alveolar lavage combined with extracorporeal membrane oxygenation: A case report. World J Clin Cases, 2020, 8(18): 4245-4251.
43. Thiagarajan RR, Barbaro RP, Rycus PT, et al. Extracorporeal Life Support Organization Registry International Report 2016. ASAIO J, 2017, 63(1): 60-67.
44. Mazzeffi M, Greenwood J, Tanaka K, et al. Bleeding, transfusion, and mortality on extracorporeal life support: ECLS Working Group on Thrombosis and Hemostasis. Ann Thorac Surg, 2016, 101(2): 682-689.
45. Sklar MC, Sy E, Lequier L, et al. Anticoagulation practices during venovenous extracorporeal membrane oxygenation for respiratory failure. A systematic review. Ann Am Thorac Soc, 2016, 13(12): 2242-2250.

Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Application and progress of extracorporeal membrane oxygenation in general thoracic surgery

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content