The newly designed transcatheter edge-to-edge mitral repair system in treating patients with severe mitral regurgitation: Two cases report_Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Authors：

ZHU Da ¹ , PAN Jiahua ¹ , LUO Zhiling ² , WANG Shouzheng ^1,3 , ZHANG Gejun ^1,3 ,  PAN Xiangbin ^1,3

1. Structural Heart Center, Fuwai Yunnan Cardiovascular Hospital, Kunming, 650102, P. R. China;
2. Department of Echocardiogram, Fuwai Yunnan Cardiovascular Hospital, Kunming, 650102, P. R. China;
3. Structural Heart Center, National Center for Cardiovascular Diseases, Fuwai Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100037, P. R. China;

Corresponding author：

PAN Xiangbin, Email: xiangbin428@hotmail.com

Keywords：

Mitral regurgitation; transcatheter edge-to-edge mitral valve repair; transfemoral vein access; case report

DOI：

10.7507/1007-4848.202110082

Video：

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Mitral regurgitation (MR) is the most common valvular heart disease, however, majority of patients are not suitable for open heart surgery due to comorbidity such as organ and heart dysfunction. Transcatheter edge-to-edge mitral valve repair has become an effective treatment option for high-risk patients with MR. Two patients were enrolled in this study inlcuding one 60-year degenerative mitral regurgitation patient and one 72-year functional mitral regurgitation patient. Transcatheter repair procedure was successfully done for the two patients without postoperative complication.

Citation： ZHU Da, PAN Jiahua, LUO Zhiling, WANG Shouzheng, ZHANG Gejun, PAN Xiangbin. The newly designed transcatheter edge-to-edge mitral repair system in treating patients with severe mitral regurgitation: Two cases report. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2022, 29(8): 1083-1086. doi: 10.7507/1007-4848.202110082 Copy

1.	Nkomo VT, Gardin JM, Skelton TN, et al. Burden of valvular heart diseases: A population-based study. Lancet, 2006, 368(9540): 1005-1011.
2.	Mauri L, Foster E, Glower DD, et al. 4-year results of a randomized controlled trial of percutaneous repair versus surgery for mitral regurgitation. J Am Coll Cardiol, 2013, 62(4): 317-328.
3.	Stone GW, Lindenfeld J, Abraham WT, et al. Transcatheter mitral-valve repair in patients with heart failure. N Engl J Med, 2018, 379(24): 2307-2318.
4.	Chakravarty T, Makar M, Patel D, et al. Transcatheter edge-to-edge mitral valve repair with the MitraClip G4 system. JACC Cardiovasc Interv, 2020, 13(20): 2402-2414.
5.	Besler C, Noack T, von Roeder M, et al. Transcatheter edge-to-edge mitral valve repair with the PASCAL system: Early results from a real-world series. EuroIntervention, 2020, 16(10): 824-832.
6.	Lee CW, Sung SH, Tsai YL, et al. Initial experience with percutaneous edge-to-edge transcatheter mitral valve repair in a tertiary medical center in Taiwan. J Chin Med Assoc, 2018, 81(4): 305-310.
7.	葛均波, 周达新, 潘文志, 等. 经导管二尖瓣修复术治疗重度二尖瓣反流的初步经验. 中华心血管病杂志, 2013, 41(2): 99-102.
8.	刘先宝, 蒲朝霞, 余蕾, 等. 经导管二尖瓣夹合术的临床结果介绍. 中国介入心脏病学杂志, 2014, 22(7): 448-451.
9.	王斌, 陈翔, 苏茂龙, 等. 新一代国产经股静脉入径经导管二尖瓣缘对缘修复系统治疗高风险功能性二尖瓣反流首例报道. 中国介入心脏病学杂志, 2021, 29(7): 416-418.
10.	Chhatriwalla AK, Vemulapalli S, Holmes DR, et al. Institutional experience with transcatheter mitral valve repair and clinical outcomes: Insights from the TVT Registry. JACC Cardiovasc Interv, 2019, 12(14): 1342-1352.

1. Nkomo VT, Gardin JM, Skelton TN, et al. Burden of valvular heart diseases: A population-based study. Lancet, 2006, 368(9540): 1005-1011.
2. Mauri L, Foster E, Glower DD, et al. 4-year results of a randomized controlled trial of percutaneous repair versus surgery for mitral regurgitation. J Am Coll Cardiol, 2013, 62(4): 317-328.
3. Stone GW, Lindenfeld J, Abraham WT, et al. Transcatheter mitral-valve repair in patients with heart failure. N Engl J Med, 2018, 379(24): 2307-2318.
4. Chakravarty T, Makar M, Patel D, et al. Transcatheter edge-to-edge mitral valve repair with the MitraClip G4 system. JACC Cardiovasc Interv, 2020, 13(20): 2402-2414.
5. Besler C, Noack T, von Roeder M, et al. Transcatheter edge-to-edge mitral valve repair with the PASCAL system: Early results from a real-world series. EuroIntervention, 2020, 16(10): 824-832.
6. Lee CW, Sung SH, Tsai YL, et al. Initial experience with percutaneous edge-to-edge transcatheter mitral valve repair in a tertiary medical center in Taiwan. J Chin Med Assoc, 2018, 81(4): 305-310.
7. 葛均波, 周达新, 潘文志, 等. 经导管二尖瓣修复术治疗重度二尖瓣反流的初步经验. 中华心血管病杂志, 2013, 41(2): 99-102.
8. 刘先宝, 蒲朝霞, 余蕾, 等. 经导管二尖瓣夹合术的临床结果介绍. 中国介入心脏病学杂志, 2014, 22(7): 448-451.
9. 王斌, 陈翔, 苏茂龙, 等. 新一代国产经股静脉入径经导管二尖瓣缘对缘修复系统治疗高风险功能性二尖瓣反流首例报道. 中国介入心脏病学杂志, 2021, 29(7): 416-418.
10. Chhatriwalla AK, Vemulapalli S, Holmes DR, et al. Institutional experience with transcatheter mitral valve repair and clinical outcomes: Insights from the TVT Registry. JACC Cardiovasc Interv, 2019, 12(14): 1342-1352.

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The newly designed transcatheter edge-to-edge mitral repair system in treating patients with severe mitral regurgitation: Two cases report

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