Scope and Techniques of Lymphadenectomy Associated with Pancreaticoduodenectomy in Surgical Treatment of Adenocarcinoma of The Head of Pancreas_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

 孙备 , 苏维宏

哈尔滨医科大学附属第一医院胰胆外科（黑龙江哈尔滨 150001）;

Corresponding author：

孙备, Email: sunbei70@tom.com

Keywords：

胰十二指肠切除术; 淋巴结清扫; 手术

DOI：

10.7507/1007-9424.20140190

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Citation： 孙备, 苏维宏. Scope and Techniques of Lymphadenectomy Associated with Pancreaticoduodenectomy in Surgical Treatment of Adenocarcinoma of The Head of Pancreas. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2014, 21(7): 789-793. doi: 10.7507/1007-9424.20140190 Copy

1.	Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013[J]. CA Cancer J Clin, 2013, 63(1): 11-30.
2.	Japanese Pancreas Society. Classification of Pancreatic Carcinoma[M]. 2nd ed. English edn. Tokyo: Kanehara & Co, Ltd., 2003.
3.	Nakao A, Harada A, Nonami T, et al. Lymph node metastases in carcinoma of the head of the pancreas region[J]. Br J Surg, 1995, 82(3): 399-402.
4.	Ishikawa O, Ohigashi H, Sasaki Y, et al. Practical grouping of positive lymph nodes in pancreatic head cancer treated by an extended pancreatectomy[J]. Surgery, 1997, 121(3): 244-249.
5.	倪泉兴, 张延龄, 蒋永剑.胰头癌淋巴结转移的临床研究[J].中国现代普通外科进展, 2004, 7(4): 232-234.
6.	崔云甫.胰腺癌淋巴转移规律的研究进展[J].肝胆胰外科杂志, 2009, 21(3): 169-172.
7.	Samra JS, Gananadha S, Hugh TJ. Surgical management of carcinoma of the head of pancreas: extended lymphadenectomy or modified en bloc resection?[J]. ANZ J Surg, 2008, 78(4): 228-236.
8.	Beger HG, Thorab FC, Liu Z, et al. Pathogenesis and treatment of neoplastic diseasesof the papilla of Vater: Kausch-Whipple procedure with lymph node dissection in cancer ofthe papilla of Vater[J]. J Hepatobiliary Pancreat Surg, 2004, 11(4): 232-238.
9.	Zacharias T, Jaeck D, Oussoultzoglou E, et al. Impact of lymph node involvement on longterm survival after R0 pancreaticoduodenectomy for ductal adenocarcinoma of the pancreas[J]. J Gastrointest Surg, 2007, 11(3): 350-356.
10.	Murakami Y, Uemura K, Sudo T, et al. Number of metastatic lymph nodes, but not lymph node ratio, is an independent prognostic factor after resection of pancreatic carcinoma[J]. J Am Coll Surg, 2010, 211(2): 196-204.
11.	Kurahara H, Takao S, Maemura K, et al. Impact of lymph node micrometastasis in patients with pancreatic head cancer[J]. World J Surg, 2007, 31(3): 483-490.
12.	Fortner JG. Regional resection of cancer of the pancreas: a newsurgical approach[J]. Surgery, 1973, 73(2): 307-320.
13.	Pedrazzoli S, Beger HG, Obertop H, et al. A surgical and pathological based classification of resective treatment of pancreatic cancer[J]. Dig Surg, 1999, 16(4): 337-345.
14.	Kawarada Y, Yokoi H, Isaji S, et al. Modified standard pancreaticoduodenectomy for the treatment of pancreatic head cancer[J]. Digestion, 1999, 60(Suppl 1): s120-s125.
15.	Nakao A, Takeda S, Inoue S, et al. Indications and techniques of extended resection for pancreatic cancer[J]. World J Surg, 2006, 30(6): 976-982.
16.	Farnell MB, Pearson RK, Sarr MG, et al. A prospective randomized trial comparing standard pancreatoduodenectomy with pancreatoduodenectomy with extended lymphadenectomy in resectable pancreatic head adenocarcinoma[J]. Surgery, 2005, 138(4): 618-630.
17.	Yeo CJ, Cameron JL, Lillemoe KD, et al. Pancreaticoduodenectomy with or without distal gastrectomy and extended retroperitoneal lymphadenectomy for periampullary adenocarcinoma, part 2: randomized controlled trial evaluating survival, morbidity, and mortality[J]. Ann Surg, 2002, 236(3): 355-368.
18.	Pedrazzoli S, DiCarlo V, Dionigi R, et al. Standard versus extended lymphadenectomy associated with pancreatoduodenectomy in the surgical treatment of adenocarcinoma of the head of the pancreas: a multicenter, prospective, randomized study. Lymphadenectomy Study Group[J]. Ann Surg, 1998, 228(4): 508-517.
19.	Nimura Y, Nagino M, Takao S, et al. Standard versus extended lymphadenectomy in radical pancreatoduodenectomy for ductal adenocarcinoma of the head of the pancreas[J]. J Hepatobiliary Pancreat Sci, 2012, 19(3): 230-241.
20.	Capussotti L, Massucco P, Ribero D, et al. Extended lymphadenectomy and vein resection for pancreatic head cancer: outcomes and implications for therapy[J]. Arch Surg, 2003, 138(12): 1316-1322.
21.	Xu X, Zhang H, Zhou P, et al. Meta-analysis of the efficacy of pancreatoduodenectomy with extended lymphadenectomy in the treatment of pancreatic cancer[J]. World J Surg Oncol, 2013, 11(1): 311.
22.	Michalski CW, Kleeff J, Wente MN, et al. Systematic review and meta-analysis of standard and extended lymphadenectomy in pancreaticoduodenectomy for pancreatic cancer[J]. Br J Surg, 2007, 94(3): 265-273.
23.	National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology; version 2. 2012.[Accessed April 16, 2013]. Available at http://www.nccn.org//professionals/physician_gls/pdf/pancreatic.pdf.
24.	郭克建.从胰腺癌生物学特性判定肿瘤的可切除性[J].中华消化外科杂志, 2007, 6(4): 252-254.
25.	Kawarada Y, Isaji S. Modified standard (D1+α) pancreaticoduodenectomy for pancreatic cancer[J]. J Gastrointest Surg, 2000, 4(3): 227-228.
26.	Jang JY, Kang MJ, Heo JS, et al. A prospective randomized controlled study comparing outcomes of standard resection and extedned resection including dissection of the nerve plexus and various lymph nodes, in patients with pancteatic head cancer[J]. Ann Surg, 2014, 259(4): 656-664.
27.	杨尹默.胰腺癌外科治疗新进展[J].中华消化外科杂志, 2013, 12(1): 16-20.
28.	Nagakawa T, Nagamori M, Futakami F, et al. Results of extensive surgery for pancreatic carcinoma[J]. Cancer, 1996, 77(4): 640-645.

1. Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013[J]. CA Cancer J Clin, 2013, 63(1): 11-30.
2. Japanese Pancreas Society. Classification of Pancreatic Carcinoma[M]. 2nd ed. English edn. Tokyo: Kanehara & Co, Ltd., 2003.
3. Nakao A, Harada A, Nonami T, et al. Lymph node metastases in carcinoma of the head of the pancreas region[J]. Br J Surg, 1995, 82(3): 399-402.
4. Ishikawa O, Ohigashi H, Sasaki Y, et al. Practical grouping of positive lymph nodes in pancreatic head cancer treated by an extended pancreatectomy[J]. Surgery, 1997, 121(3): 244-249.
5. 倪泉兴, 张延龄, 蒋永剑.胰头癌淋巴结转移的临床研究[J].中国现代普通外科进展, 2004, 7(4): 232-234.
6. 崔云甫.胰腺癌淋巴转移规律的研究进展[J].肝胆胰外科杂志, 2009, 21(3): 169-172.
7. Samra JS, Gananadha S, Hugh TJ. Surgical management of carcinoma of the head of pancreas: extended lymphadenectomy or modified en bloc resection?[J]. ANZ J Surg, 2008, 78(4): 228-236.
8. Beger HG, Thorab FC, Liu Z, et al. Pathogenesis and treatment of neoplastic diseasesof the papilla of Vater: Kausch-Whipple procedure with lymph node dissection in cancer ofthe papilla of Vater[J]. J Hepatobiliary Pancreat Surg, 2004, 11(4): 232-238.
9. Zacharias T, Jaeck D, Oussoultzoglou E, et al. Impact of lymph node involvement on longterm survival after R0 pancreaticoduodenectomy for ductal adenocarcinoma of the pancreas[J]. J Gastrointest Surg, 2007, 11(3): 350-356.
10. Murakami Y, Uemura K, Sudo T, et al. Number of metastatic lymph nodes, but not lymph node ratio, is an independent prognostic factor after resection of pancreatic carcinoma[J]. J Am Coll Surg, 2010, 211(2): 196-204.
11. Kurahara H, Takao S, Maemura K, et al. Impact of lymph node micrometastasis in patients with pancreatic head cancer[J]. World J Surg, 2007, 31(3): 483-490.
12. Fortner JG. Regional resection of cancer of the pancreas: a newsurgical approach[J]. Surgery, 1973, 73(2): 307-320.
13. Pedrazzoli S, Beger HG, Obertop H, et al. A surgical and pathological based classification of resective treatment of pancreatic cancer[J]. Dig Surg, 1999, 16(4): 337-345.
14. Kawarada Y, Yokoi H, Isaji S, et al. Modified standard pancreaticoduodenectomy for the treatment of pancreatic head cancer[J]. Digestion, 1999, 60(Suppl 1): s120-s125.
15. Nakao A, Takeda S, Inoue S, et al. Indications and techniques of extended resection for pancreatic cancer[J]. World J Surg, 2006, 30(6): 976-982.
16. Farnell MB, Pearson RK, Sarr MG, et al. A prospective randomized trial comparing standard pancreatoduodenectomy with pancreatoduodenectomy with extended lymphadenectomy in resectable pancreatic head adenocarcinoma[J]. Surgery, 2005, 138(4): 618-630.
17. Yeo CJ, Cameron JL, Lillemoe KD, et al. Pancreaticoduodenectomy with or without distal gastrectomy and extended retroperitoneal lymphadenectomy for periampullary adenocarcinoma, part 2: randomized controlled trial evaluating survival, morbidity, and mortality[J]. Ann Surg, 2002, 236(3): 355-368.
18. Pedrazzoli S, DiCarlo V, Dionigi R, et al. Standard versus extended lymphadenectomy associated with pancreatoduodenectomy in the surgical treatment of adenocarcinoma of the head of the pancreas: a multicenter, prospective, randomized study. Lymphadenectomy Study Group[J]. Ann Surg, 1998, 228(4): 508-517.
19. Nimura Y, Nagino M, Takao S, et al. Standard versus extended lymphadenectomy in radical pancreatoduodenectomy for ductal adenocarcinoma of the head of the pancreas[J]. J Hepatobiliary Pancreat Sci, 2012, 19(3): 230-241.
20. Capussotti L, Massucco P, Ribero D, et al. Extended lymphadenectomy and vein resection for pancreatic head cancer: outcomes and implications for therapy[J]. Arch Surg, 2003, 138(12): 1316-1322.
21. Xu X, Zhang H, Zhou P, et al. Meta-analysis of the efficacy of pancreatoduodenectomy with extended lymphadenectomy in the treatment of pancreatic cancer[J]. World J Surg Oncol, 2013, 11(1): 311.
22. Michalski CW, Kleeff J, Wente MN, et al. Systematic review and meta-analysis of standard and extended lymphadenectomy in pancreaticoduodenectomy for pancreatic cancer[J]. Br J Surg, 2007, 94(3): 265-273.
23. National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology; version 2. 2012.[Accessed April 16, 2013]. Available at http://www.nccn.org//professionals/physician_gls/pdf/pancreatic.pdf.
24. 郭克建.从胰腺癌生物学特性判定肿瘤的可切除性[J].中华消化外科杂志, 2007, 6(4): 252-254.
25. Kawarada Y, Isaji S. Modified standard (D1+α) pancreaticoduodenectomy for pancreatic cancer[J]. J Gastrointest Surg, 2000, 4(3): 227-228.
26. Jang JY, Kang MJ, Heo JS, et al. A prospective randomized controlled study comparing outcomes of standard resection and extedned resection including dissection of the nerve plexus and various lymph nodes, in patients with pancteatic head cancer[J]. Ann Surg, 2014, 259(4): 656-664.
27. 杨尹默.胰腺癌外科治疗新进展[J].中华消化外科杂志, 2013, 12(1): 16-20.
28. Nagakawa T, Nagamori M, Futakami F, et al. Results of extensive surgery for pancreatic carcinoma[J]. Cancer, 1996, 77(4): 640-645.

Next Article
Application on Evaluation of Resectable Range of 3D Imaging Technology Before Pancreatoduodenectomy

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Scope and Techniques of Lymphadenectomy Associated with Pancreaticoduodenectomy in Surgical Treatment of Adenocarcinoma of The Head of Pancreas

Abstract Full text Figures/Tables Video References Cited by

Next Article

Format

Content