Experience of Laparoscopic Pancreaticoduodenectomy in Treatment of 45 Patients with Periampullary Diseases_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

 ZHANGHua , WANGMing-jun , WANGXin , ALi ,  PENGBing

Department of Hepatopancreatobiliary Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China;

Corresponding author：

PENGBing, Email: pengbing84@hotmail.Com

Keywords：

Periampullary disease; Laparoscope; Pancreaticoduodenectomy; Pylorus preserving pancreaticoduodenectomy

DOI：

10.7507/1007-9424.20140226

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To investigate the feasibility and security of laparoscopic Whipple pancreaticoduodenectomy(LPD)or laparoscopic pylorus preserving pancreaticoduodenectomy(LPPPD)for the patients with periampullary diseases, estimate the ratio of postoperative complications between LPD and LPPPD. Methods Fourty-five patients who underwent the LPD or LPPPD from January 2010 to March 2014 were reviewed retrospectively. These patients were divided into LPD group and LPPPD group basing on the Whipple or polyrus preservation. Results Among these 45 patients, 25 patients were performed the LPD, the other 20 patients were performed the LPPPD. There were 25(55.56%)complications after operation, including 10 cases of pancreatic fistula, 1 case of bile leakage, 6 cases of delayed gastric emptying, 3 cases of infection, 2 cases of stomach intestine stomatorrhagia, 1 case of mesenteric venous thrombosis, 1 case of ascites, 1 case of chylous fistula. The complication rate had no significant difference between two groups. One patient died after operation in the LPPPD group. Conclusion Laparoscopic pancreaticoduodenectomy is safe and feasible in the treatment of periampullary diseases, the LPPPD could partly prevent the occurrence of reflux of the digestive juice following the resection of pylorus and improve the quality of life.

Citation： ZHANGHua, WANGMing-jun, WANGXin, ALi, PENGBing. Experience of Laparoscopic Pancreaticoduodenectomy in Treatment of 45 Patients with Periampullary Diseases. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2014, 21(8): 940-945. doi: 10.7507/1007-9424.20140226 Copy

1.	Tran KT, Smeenk HG, van Eijck CH, et al. Pylorus preserving pancreaticoduodenectomy versus standard Whipple procedure: a prospective, randomized, multicenter analysis of 170 patients with pancreatic and periampullary tumors[J]. Ann Surg, 2004, 240(5): 738-745.
2.	刘战培, 蒲青凡, 周勇. 233例胰十二指肠切除术后并发症及死亡危险因素多因素分析[J].中国普外基础与临床杂志, 2008, 15(3): 195-200.
3.	Alsaif F. Pylorus preserving pancreaticoduodenectomy for periampullary carcinoma, is it a good option?[J]. Saudi J Gastroenterol, 2010, 16(2): 75-78.
4.	Kohsari MR, Riazi H, Akbar MH. Outcome of pancreaticoduodenectomy: comparing the classic Whipple with pyloric preservation[J]. Saudi J Gastroenterol, 2004, 10(3): 144-149.
5.	张超, 龚昭, 夏辉.腹腔镜与开腹胰十二指肠切除术效果比较[J].现代中西医结合杂志, 2014, 23(7): 719-721.
6.	Gagner M, Pomp A. Laparoscopic pylorus-preserving pancreatoduodenectomy[J]. Surg Endosc, 1994, 8(5): 408-410.
7.	卢榜裕, 陆文奇, 李杰, 等.电视腹腔镜胰十二指肠切除术5例报告[J].中国微创外科杂志, 2005, 5(11): 877-879.
8.	袁涛, 邓少丽, 顾红光, 等. 156例胰十二指肠切除术临床分析[J].中国现代医学杂志, 2009, 19(19): 3035-3037.
9.	蒋金伟, 黄国强, 唐勇, 等. 68例胰十二指肠切除术后早期并发症危险因素分析[J].重庆医科大学学报, 2010, 35(3): 457-460.
10.	纪伟平, 邵卓, 沈力, 等.胰十二指肠切除术后乳糜漏的成因分析和治疗手段[J].肝胆胰外科杂志, 2013, 26(1): 12-15.
11.	刘强.胰十二指肠切除术并发症临床分析[J].中外医学研究, 2014, 12(13): 122-123.
12.	王志才.胰十二指肠切除61例临床分析[J].临床和实验医学杂志, 2007, 6(10): 111.
13.	Kendrick ML, Cusati D. Total laparoscopic pancreaticoduodenectomy: feasibility and outcome in an early experience[J]. Arch Surg, 2010, 145(1): 19-23.
14.	周涛, 郝伏龙, 张伟.完全腹腔镜与开腹手术行胰十二指肠切除的临床效果比较[J].实用医院临床杂志, 2013, 10(4): 185-187.
15.	Adam U, Makowiec F, Riediger H, et al. Risk factors for complications after pancreatic head resection[J]. Am J Surg, 2004, 187(2): 201-208.
16.	吴传有, 刘长安, 李生伟, 等.胰十二指肠切除术后胰瘘的预防[J].现代临床医学, 2014, 40(2): 86-88.
17.	Cameron JL. Whipple or pylorus preservation? A critical reappraisal and some new insights into pancreaticoduodenectomy[J]. Ann Surg, 2000, 231(3): 301-302.
18.	Kozuschek W. Cephalic duodenopancreatectomy with pylorus preservation. An experience of 52 surgically-treated cases[J]. Chirurgie, 1991, 117(5/6): 423-430.
19.	Karanicolas PJ, Davies E, Kunz R, et al. The pylorus: take it or leave it? Systematic review and meta-analysis of pylorus-preserving versus standard Whipple pancreaticoduodenectomy for pancreatic or periampullary cancer[J]. Ann Surg Oncol, 2007, 14(6): 1825-1834.
20.	Seiler CA, Wagner M, Bachmann T, et al. Randomized clinical trial of pylorus-preserving duodenopancreatectomy versus classical Whipple resection-long term results[J]. Br J Surg, 2005, 92(5): 547-556.
21.	Horstmann O, Markus PM, Ghadimi MB, et al. Pylorus preservation has no impact on delayed gastric emptying after pancreatic head resection[J]. Pancreas, 2004, 28(1): 69-74.
22.	Akizuki E, Kimura Y, Nobuoka T, et al. Prospective nonrandomized comparison between pylorus-preserving and subtotal stomachpreserving pancreaticoduodenectomy from the perspectives of DGE occurrence and postoperative digestive functions[J]. J Gastrointest Surg, 2008, 12(7): 1185-1192.
23.	Iqbal N, Lovegrove RE, Tilney HS, et al. A comparison of pancreaticoduodenectomy with pylorus preserving pancreaticoduodenectomy: a meta-analysis of 2822 patients[J]. Eur J Surg Oncol, 2008, 34(11): 1237-1245.
24.	Zerbi A, Balzano G, Patuzzo R, et al. Comparison between pylorus-preserving and Whipple pancreatoduodenectomy[J]. Br J Surg, 1995, 82(7): 975-979.
25.	Yamaguchi K, Kishinaka M, Nagai E, et al. Pancreatoduodenectomy for pancreatic head carcinoma with or without pylorus preservation[J]. Hepatogastroenterology, 2001, 48(41): 1479-1485.
26.	黄泽坚, 张磊, 彭孝雄, 等.降低胰十二指肠切除术后外科并发症的临床体会[J].岭南现代临床外科, 2010, 10(4): 256-258.
27.	Bell RH Jr. Pancreaticoduodenectomy with or without pylorus preservation have similar outcomes[J]. Cancer Treat Rev, 2005, 31(4): 328-331.
28.	Mosca F, Giulianotti PC, Balestracci T, et al. Long-term survival in pancreatic Cancer: pylorus-preserving versus Whipple pancreatoduodenectomy[J]. Surgery, 1997, 122(3): 553-566.

1. Tran KT, Smeenk HG, van Eijck CH, et al. Pylorus preserving pancreaticoduodenectomy versus standard Whipple procedure: a prospective, randomized, multicenter analysis of 170 patients with pancreatic and periampullary tumors[J]. Ann Surg, 2004, 240(5): 738-745.
2. 刘战培, 蒲青凡, 周勇. 233例胰十二指肠切除术后并发症及死亡危险因素多因素分析[J].中国普外基础与临床杂志, 2008, 15(3): 195-200.
3. Alsaif F. Pylorus preserving pancreaticoduodenectomy for periampullary carcinoma, is it a good option?[J]. Saudi J Gastroenterol, 2010, 16(2): 75-78.
4. Kohsari MR, Riazi H, Akbar MH. Outcome of pancreaticoduodenectomy: comparing the classic Whipple with pyloric preservation[J]. Saudi J Gastroenterol, 2004, 10(3): 144-149.
5. 张超, 龚昭, 夏辉.腹腔镜与开腹胰十二指肠切除术效果比较[J].现代中西医结合杂志, 2014, 23(7): 719-721.
6. Gagner M, Pomp A. Laparoscopic pylorus-preserving pancreatoduodenectomy[J]. Surg Endosc, 1994, 8(5): 408-410.
7. 卢榜裕, 陆文奇, 李杰, 等.电视腹腔镜胰十二指肠切除术5例报告[J].中国微创外科杂志, 2005, 5(11): 877-879.
8. 袁涛, 邓少丽, 顾红光, 等. 156例胰十二指肠切除术临床分析[J].中国现代医学杂志, 2009, 19(19): 3035-3037.
9. 蒋金伟, 黄国强, 唐勇, 等. 68例胰十二指肠切除术后早期并发症危险因素分析[J].重庆医科大学学报, 2010, 35(3): 457-460.
10. 纪伟平, 邵卓, 沈力, 等.胰十二指肠切除术后乳糜漏的成因分析和治疗手段[J].肝胆胰外科杂志, 2013, 26(1): 12-15.
11. 刘强.胰十二指肠切除术并发症临床分析[J].中外医学研究, 2014, 12(13): 122-123.
12. 王志才.胰十二指肠切除61例临床分析[J].临床和实验医学杂志, 2007, 6(10): 111.
13. Kendrick ML, Cusati D. Total laparoscopic pancreaticoduodenectomy: feasibility and outcome in an early experience[J]. Arch Surg, 2010, 145(1): 19-23.
14. 周涛, 郝伏龙, 张伟.完全腹腔镜与开腹手术行胰十二指肠切除的临床效果比较[J].实用医院临床杂志, 2013, 10(4): 185-187.
15. Adam U, Makowiec F, Riediger H, et al. Risk factors for complications after pancreatic head resection[J]. Am J Surg, 2004, 187(2): 201-208.
16. 吴传有, 刘长安, 李生伟, 等.胰十二指肠切除术后胰瘘的预防[J].现代临床医学, 2014, 40(2): 86-88.
17. Cameron JL. Whipple or pylorus preservation? A critical reappraisal and some new insights into pancreaticoduodenectomy[J]. Ann Surg, 2000, 231(3): 301-302.
18. Kozuschek W. Cephalic duodenopancreatectomy with pylorus preservation. An experience of 52 surgically-treated cases[J]. Chirurgie, 1991, 117(5/6): 423-430.
19. Karanicolas PJ, Davies E, Kunz R, et al. The pylorus: take it or leave it? Systematic review and meta-analysis of pylorus-preserving versus standard Whipple pancreaticoduodenectomy for pancreatic or periampullary cancer[J]. Ann Surg Oncol, 2007, 14(6): 1825-1834.
20. Seiler CA, Wagner M, Bachmann T, et al. Randomized clinical trial of pylorus-preserving duodenopancreatectomy versus classical Whipple resection-long term results[J]. Br J Surg, 2005, 92(5): 547-556.
21. Horstmann O, Markus PM, Ghadimi MB, et al. Pylorus preservation has no impact on delayed gastric emptying after pancreatic head resection[J]. Pancreas, 2004, 28(1): 69-74.
22. Akizuki E, Kimura Y, Nobuoka T, et al. Prospective nonrandomized comparison between pylorus-preserving and subtotal stomachpreserving pancreaticoduodenectomy from the perspectives of DGE occurrence and postoperative digestive functions[J]. J Gastrointest Surg, 2008, 12(7): 1185-1192.
23. Iqbal N, Lovegrove RE, Tilney HS, et al. A comparison of pancreaticoduodenectomy with pylorus preserving pancreaticoduodenectomy: a meta-analysis of 2822 patients[J]. Eur J Surg Oncol, 2008, 34(11): 1237-1245.
24. Zerbi A, Balzano G, Patuzzo R, et al. Comparison between pylorus-preserving and Whipple pancreatoduodenectomy[J]. Br J Surg, 1995, 82(7): 975-979.
25. Yamaguchi K, Kishinaka M, Nagai E, et al. Pancreatoduodenectomy for pancreatic head carcinoma with or without pylorus preservation[J]. Hepatogastroenterology, 2001, 48(41): 1479-1485.
26. 黄泽坚, 张磊, 彭孝雄, 等.降低胰十二指肠切除术后外科并发症的临床体会[J].岭南现代临床外科, 2010, 10(4): 256-258.
27. Bell RH Jr. Pancreaticoduodenectomy with or without pylorus preservation have similar outcomes[J]. Cancer Treat Rev, 2005, 31(4): 328-331.
28. Mosca F, Giulianotti PC, Balestracci T, et al. Long-term survival in pancreatic Cancer: pylorus-preserving versus Whipple pancreatoduodenectomy[J]. Surgery, 1997, 122(3): 553-566.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Experience of Laparoscopic Pancreaticoduodenectomy in Treatment of 45 Patients with Periampullary Diseases

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content