肝内胆管囊腺癌7例诊治分析_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

 姚俊超 , 郭大伟 , 姜堃 , 郭金帅 , 孙文郁 , 林琳 , 梁健 ,  姜晓峰

中国医科大学附属第四医院普外科（辽宁沈阳 110032）;

Corresponding author：

姜晓峰, Email: jxf0426@hotmail.com

Keywords：

肝内胆管囊腺癌; 临床特点; 诊断; 治疗

DOI：

10.7507/1007-9424.20150091

Video：

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目的总结肝内胆管囊腺癌的诊断及治疗方法。方法回顾性分析笔者所在医院2000年4月至2013年7月期间收治的7例肝内胆管囊腺癌患者的临床资料。结果 7例患者均经实验室检查和影像学检查初步诊断为肝脏占位，但确诊依据的是术后病理学检查。5例行根治性手术切除，其中4例行半肝切除术（非浸润型），随访期间均存活，1例行囊壁完整切除术（浸润型）者于术后18个月死亡；1例行囊壁大部分切除术（浸润型），于术后12个月死亡；1例行彩超引导下的肝脏穿刺囊内积液引流、细针穿刺活检术（浸润型），于术后7个月死亡。结论肝内胆管囊腺癌的影像学表现多为肝脏囊性病变，但确诊仍需病理学检查。肝内胆管囊腺癌局限于囊内者，通过行完整切除即可获得较满意的临床疗效；而癌细胞向囊壁外肝组织浸润生长者的预后差，生存时间短。

Citation： 姚俊超, 郭大伟, 姜堃, 郭金帅, 孙文郁, 林琳, 梁健, 姜晓峰. 肝内胆管囊腺癌7例诊治分析. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2015, 22(3): 343-345. doi: 10.7507/1007-9424.20150091 Copy

1.	Zen Y, Fujii T, Itatsu K, et al. Biliary cystic tumors with bile duct communication:a cystic variant of intraductal papillary neoplasm of the bile duct. Mod Pathol, 2006, 19(9):1243-1254.
2.	Tucek S, Tomasek J, Halámkova J, et al. Bile duct malignancies. Klin Onkol, 2010, 23(4):231-241.
3.	Chen YW, Li CH, Liu Z, et al. Surgical management of biliary cystadenoma and cystadenocarcinoma of the liver. Genet Mol Res, 2014, 13(3):6383-6390.
4.	Suh JI, Kim JH, Lee DJ, et al. A case of biliary cystadenocarcinoma. Korean J Intern Med, 1997, 12(1):109-113.
5.	Nakajima T, Sugano I, Matsuzaki O, et al. Biliary cystadenocarci-noma of the liver. A clinicopathologic and histochemical evaluation of nine cases. Cancer, 1992, 69(10):2426-2432.
6.	Kubota E, Katsumi K, Iida M, et al. Biliary cystadenocarcinoma followed up as benign cystadenoma for 10 years. J Gastroenterol, 2003, 38(3):278-282.
7.	Erdogan D, Busch OR, Rauws EA, et al. Obstructive jaundice due to hepatobiliary cystadenoma or cystadenocarcinoma. World J Gastroenterol, 2006, 12(35):5735-5738.
8.	Kim HG. Biliary cystic neoplasm:biliary cystadenoma and biliary cystadenocarcinoma. Korean J Gastroenterol, 2006, 47(1):5-14.
9.	Salerno S, Florena AM, Romano I, et al. Multifocal biliary cystadenocarcinoma of the liver:CT and pathological findings. Tumori, 2006, 92(4):358-360.
10.	Wang C, Miao R, Liu H, et al. Intrahepatic biliary cystadenoma and cystadenocarcinoma:an experience of 30 cases. Dig Liver Dis, 2012, 44(5):426-431.
11.	李鑫, 张佳林, 宋少伟, 等. 肝胆管囊腺瘤和囊腺癌诊治7例. 世界华人消化杂志, 2008, 16(11):1244-1247.
12.	Koffron A, Rao S, Ferrario M, et al. Intrahepatic biliary cystadenoma:role of cyst fluid analysis and surgical management in the laparos-copic era. Surgery, 2004, 136(4):926-933.
13.	Delis SG, Touloumis Z, Bakoyiannis AA, et al. Intrahepatic biliary cystadenoma:a need for radical resection. Eur J Gastroenterol Hepatol, 2008, 20(1):10-14.
14.	Soares KC, Arnaoutakis DJ, Kamel I, et al. Cystic neoplasms of the liver:biliary cystadenoma and cystadenocarcinoma. J Am Coll Surg, 2014, 218(1):119-128.
15.	Thomas KT, Welch D, Trueblood A, et al. Effective treatment of biliary cystadenoma. Ann Surg, 2005, 241(5):769-775.

1. Zen Y, Fujii T, Itatsu K, et al. Biliary cystic tumors with bile duct communication:a cystic variant of intraductal papillary neoplasm of the bile duct. Mod Pathol, 2006, 19(9):1243-1254.
2. Tucek S, Tomasek J, Halámkova J, et al. Bile duct malignancies. Klin Onkol, 2010, 23(4):231-241.
3. Chen YW, Li CH, Liu Z, et al. Surgical management of biliary cystadenoma and cystadenocarcinoma of the liver. Genet Mol Res, 2014, 13(3):6383-6390.
4. Suh JI, Kim JH, Lee DJ, et al. A case of biliary cystadenocarcinoma. Korean J Intern Med, 1997, 12(1):109-113.
5. Nakajima T, Sugano I, Matsuzaki O, et al. Biliary cystadenocarci-noma of the liver. A clinicopathologic and histochemical evaluation of nine cases. Cancer, 1992, 69(10):2426-2432.
6. Kubota E, Katsumi K, Iida M, et al. Biliary cystadenocarcinoma followed up as benign cystadenoma for 10 years. J Gastroenterol, 2003, 38(3):278-282.
7. Erdogan D, Busch OR, Rauws EA, et al. Obstructive jaundice due to hepatobiliary cystadenoma or cystadenocarcinoma. World J Gastroenterol, 2006, 12(35):5735-5738.
8. Kim HG. Biliary cystic neoplasm:biliary cystadenoma and biliary cystadenocarcinoma. Korean J Gastroenterol, 2006, 47(1):5-14.
9. Salerno S, Florena AM, Romano I, et al. Multifocal biliary cystadenocarcinoma of the liver:CT and pathological findings. Tumori, 2006, 92(4):358-360.
10. Wang C, Miao R, Liu H, et al. Intrahepatic biliary cystadenoma and cystadenocarcinoma:an experience of 30 cases. Dig Liver Dis, 2012, 44(5):426-431.
11. 李鑫, 张佳林, 宋少伟, 等. 肝胆管囊腺瘤和囊腺癌诊治7例. 世界华人消化杂志, 2008, 16(11):1244-1247.
12. Koffron A, Rao S, Ferrario M, et al. Intrahepatic biliary cystadenoma:role of cyst fluid analysis and surgical management in the laparos-copic era. Surgery, 2004, 136(4):926-933.
13. Delis SG, Touloumis Z, Bakoyiannis AA, et al. Intrahepatic biliary cystadenoma:a need for radical resection. Eur J Gastroenterol Hepatol, 2008, 20(1):10-14.
14. Soares KC, Arnaoutakis DJ, Kamel I, et al. Cystic neoplasms of the liver:biliary cystadenoma and cystadenocarcinoma. J Am Coll Surg, 2014, 218(1):119-128.
15. Thomas KT, Welch D, Trueblood A, et al. Effective treatment of biliary cystadenoma. Ann Surg, 2005, 241(5):769-775.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

肝内胆管囊腺癌7例诊治分析

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