• Department of General Surgery, Central Hospital of Huangpu District, Shanghai 200002, China;
CAILin-gang, Email: clg1980628@aliyun.com
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Objective To review the research progress of the relationship between the insulin resistance, insulin-like growth factor-Ⅰ(IGF-Ⅰ), insulin-like growth factor-Ⅱ(IGF-Ⅱ), and colorectal cancer, and to explore the future research trends. Methods The related literatures in recent 5 years from abroad databases (PubMed, Web of Science, and EMBASE)and domestic databases (CNKI, WANFANG, and WEIPU)were collected and reviewed. Results The research on the correlation between the changes and colorectal cancer with insulin resistance and IGF-Ⅰand IGF-Ⅱlevels, epidemiological studies and the mechanism research, indicates that there are complex and close relationship between them. Conclusions The research about the relationship between the insulin resistance, IGF-Ⅰ, IGF-Ⅱ, and colorectal cancer is promising.However, many issues need to be further investigated.

Citation: CAILin-gang, LIQi-ju. Research Progress of The Relationship Between The Insulin Resistance, IGF-Ⅰ, IGF-Ⅱ, and Colorectal Cancer. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2015, 22(4): 509-512. doi: 10.7507/1007-9424.20150135 Copy

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