Surgical Treatment of Malignant Tumors at Caudate Lobe of Liver in 51 Cases_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

 SUZi-ting ,  ZENGZhong , DUANJian , HUANGHan-fei , LINJie , XUWang-gang , HUANGZhi

Department of Organ Transplantation Center, The First Affiliated Hospital of Kunming Medical University, Kunming 650032, Yunnan Province, China;

Corresponding author：

ZENGZhong, Email: zzong1111@126.com

Keywords：

malignant tumor at caudate lobe of liver; Caudate lobectomy; Retrograde caudate lobectomy

DOI：

10.7507/1007-9424.20150174

Video：

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Objective To review the clinical experience and evaluate the results in patients who underwent caudate lobectomy for malignant tumor at caudate lobe of liver. Methods Clinicopathological characteristics of 51 patients who underwent caudate lobectomy because of malignant tumors at caudate lobe of liver in our hospital from May 2007 to December 2013 were reviewed retrospectively, and operative detail, complication rate, and survival rate were described. Results The cancer were resected successfully in 51 patients with malignant tumors at caudate lobe of liver. Thirty patients were performed isolated caudate lobectomy and 21 patients performed combined lobectomy. Of the 51 patients, 9 patients were treated with retrograde caudate lobectomy. The operation time was 180.0-360.0 min, with the average value of 244.0 min. The bleeding volume was 400.0-1 000.0 mL, with the average value of 630.0 mL. In all patients, there was no perioperative death and no postoperative bleeding happened, and 17 patients who suffered from interrelated complications were cured or got better by conservative treatments. Fifty-one patients were followed up for 6-60 months, and the median survival time was 38.0 months. During the follow-up period, 29 patients dead, 21 patients suffered from recurrence, and 12 patients suffered from metastasis. The cumulative survival rates of 1-, 3-, and 5-year were 76.1%, 54.7%, and 31.8% respectively after caudate lobectomy. Conclusion The caudate lobectomy in treatment of malignant tumor at caudate lobe of liver is effective and feasible.

Citation： SUZi-ting, ZENGZhong, DUANJian, HUANGHan-fei, LINJie, XUWang-gang, HUANGZhi. Surgical Treatment of Malignant Tumors at Caudate Lobe of Liver in 51 Cases. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2015, 22(6): 671-675. doi: 10.7507/1007-9424.20150174 Copy

1.	Peng SY. Hepatic caudate lobe resection. Heidelberg:Springer Berlin Heidelberg, 2010:1-14.
2.	Wahab MA, Fathy O, Elhanafy E, et al. Caudate lobe resection for hepatocellular carcinoma. Hepatogastroenterology, 2011, 58(112):1904-1908.
3.	Midorikawa Y, Takayama T. Caudate lobectomy (segmentectomy 1). J Hepatobiliary Pancreat Sci, 2012, 19(1):48-53.
4.	Kumon M. Anatomy of the caudate lobe with special reference to portal vein and bile duct. Acta Hepatol Jpn, 1985, 26(9):1193-1199.
5.	Bartlett D, Fong Y, Blumgart LH. Complete resection of the caudate lobe of the liver:technique and results. Br J Surg, 1996, 83(8):1076-1081.
6.	Kogure K, Kuwano H, Fujimaki N, et al. Relation among portal segmentation, proper hepatic vein, and external notch of the caudate lobe in the human liver. Ann Surg, 2000, 231(2):223-228.
7.	Sato TJ, Hirai I, Murakami G, et al. An anatomical study of short hepatic veins, with special reference to delineation of the caudate lobe for hanging maneuver of the liver without the usual mobilization. J Hepatobiliary Pancreat Surg, 2002, 9(1):55-60.
8.	Kapoor S. Caudate lobectomy:tumor location, topographic classification, and technique using right-and left-sided approaches to the liver. Am J Surg, 2009, 198(2):298-299.
9.	Wang ZG, Lau W, Fu SY, et al. Anterior hepatic parenchymal transection for complete caudate lobectomy to treat liver cancer situated in or involving the paracaval portion of the caudate lobe. J Gastrointest Surg, 2015, [Epub ahead of print].
10.	Sakamoto Y, Nara S, Hata S, et al. Prognosis of patients undergoing hepatectomy for solitary hepatocellular carcinoma originating in the caudate lobe. Surgery, 2011, 150(5):959-967.
11.	Shimizu H, Kimura F, Yoshidome H, et al. Aggressive surgical resection for hilar cholangiocarcinoma of the left-side predominance:radicality and safety of left-sided hepatectomy. Ann Surg, 2010, 251(2):281-286.
12.	Yang JH, Gu J, Dong P, et al. Isolated complete caudate lobectomy for hepatic tumor of the anterior transhepatic approach:surgical approaches and perioperative outcomes. World J Surg Oncol, 2013, 11:197.
13.	Lee SG, Hwang S, Jung JP, et al. Outcome of patients with huge hepatocellular carcinoma after primary resection and treatment of recurrent lesions. Br J Surg, 2007, 94(3):320-326.
14.	王许安, 吴向嵩, 李茂岚, 等.单独肝尾状叶切除术策略更新(附21例报告).中国实用外科杂志, 2014, 34(8):754-756.
15.	黄志强.单独肝尾状叶全切除术.消化外科, 2002, 1(1):62-65.
16.	黄志强, 周宁新, 黄晓强, 等.尾状叶外科——肝外科的最后领域.消化外科, 2004, 3(1):1-17.
17.	Peng SY, Liu YB, Wang JW, et al. Retrograde resection of caudate lobe of liver. J Am Coll Surg, 2008, 206(3):1232-1238.
18.	汪珍光, 傅思源, 周伟平, 等.逆行右半肝联合全尾状叶肿瘤切除术.中华消化外科杂志, 2013, 12(9):655-658.
19.	Nanashima A, Tobinaga S, Abo T, et al. Left hepatectomy accompanied by a resection of the whole caudate lobe using the dorsally fixed liver-hanging maneuver. Surg Today, 2011, 41(3):453-458.
20.	Oya H, Sato Y, Yamamoto S, et al. A new technique of lateral approach for laparoscopy-assisted donor left hepatectomy. Hepatogastroenterology, 2011, 58(110-111):1765-1768.
21.	匡铭, 汤地, 王晔, 等.三维手术模拟系统在肝癌患者精准肝切除中的应用.中国普外基础与临床杂志, 2011, 18(7):682-687.
22.	皮勇, 谢飞, 寇丽.尾状叶与非尾状叶肝癌手术切除疗效对比观察.安徽医药, 2014, 18(9):1686-1689.
23.	娄尧强, 江献川, 彭淑牖, 等.肝脏恶性肿瘤682例手术治疗分析.中华外科杂志, 2004, 42(9):513-516.
24.	王培培, 王军, 齐曼, 等.直肠癌术后三维适形/调强放疗联合化疗与单纯辅助化疗的疗效比较.肿瘤防治研究, 2014, 45(5):468-473.
25.	Jones RM, Moulton CE, Hardy KJ. Central venous pressure and its effect on blood loss during liver resection. Br J Surg, 1998, 85(8):1058-1060.
26.	彭淑牖, 刘颖斌, 许斌, 等.肝静脉和下腔静脉血流控制在高难度肝肿瘤切除中的应用.中华外科杂志, 2004, 42(5):260-264.

1. Peng SY. Hepatic caudate lobe resection. Heidelberg:Springer Berlin Heidelberg, 2010:1-14.
2. Wahab MA, Fathy O, Elhanafy E, et al. Caudate lobe resection for hepatocellular carcinoma. Hepatogastroenterology, 2011, 58(112):1904-1908.
3. Midorikawa Y, Takayama T. Caudate lobectomy (segmentectomy 1). J Hepatobiliary Pancreat Sci, 2012, 19(1):48-53.
4. Kumon M. Anatomy of the caudate lobe with special reference to portal vein and bile duct. Acta Hepatol Jpn, 1985, 26(9):1193-1199.
5. Bartlett D, Fong Y, Blumgart LH. Complete resection of the caudate lobe of the liver:technique and results. Br J Surg, 1996, 83(8):1076-1081.
6. Kogure K, Kuwano H, Fujimaki N, et al. Relation among portal segmentation, proper hepatic vein, and external notch of the caudate lobe in the human liver. Ann Surg, 2000, 231(2):223-228.
7. Sato TJ, Hirai I, Murakami G, et al. An anatomical study of short hepatic veins, with special reference to delineation of the caudate lobe for hanging maneuver of the liver without the usual mobilization. J Hepatobiliary Pancreat Surg, 2002, 9(1):55-60.
8. Kapoor S. Caudate lobectomy:tumor location, topographic classification, and technique using right-and left-sided approaches to the liver. Am J Surg, 2009, 198(2):298-299.
9. Wang ZG, Lau W, Fu SY, et al. Anterior hepatic parenchymal transection for complete caudate lobectomy to treat liver cancer situated in or involving the paracaval portion of the caudate lobe. J Gastrointest Surg, 2015, [Epub ahead of print].
10. Sakamoto Y, Nara S, Hata S, et al. Prognosis of patients undergoing hepatectomy for solitary hepatocellular carcinoma originating in the caudate lobe. Surgery, 2011, 150(5):959-967.
11. Shimizu H, Kimura F, Yoshidome H, et al. Aggressive surgical resection for hilar cholangiocarcinoma of the left-side predominance:radicality and safety of left-sided hepatectomy. Ann Surg, 2010, 251(2):281-286.
12. Yang JH, Gu J, Dong P, et al. Isolated complete caudate lobectomy for hepatic tumor of the anterior transhepatic approach:surgical approaches and perioperative outcomes. World J Surg Oncol, 2013, 11:197.
13. Lee SG, Hwang S, Jung JP, et al. Outcome of patients with huge hepatocellular carcinoma after primary resection and treatment of recurrent lesions. Br J Surg, 2007, 94(3):320-326.
14. 王许安, 吴向嵩, 李茂岚, 等.单独肝尾状叶切除术策略更新(附21例报告).中国实用外科杂志, 2014, 34(8):754-756.
15. 黄志强.单独肝尾状叶全切除术.消化外科, 2002, 1(1):62-65.
16. 黄志强, 周宁新, 黄晓强, 等.尾状叶外科——肝外科的最后领域.消化外科, 2004, 3(1):1-17.
17. Peng SY, Liu YB, Wang JW, et al. Retrograde resection of caudate lobe of liver. J Am Coll Surg, 2008, 206(3):1232-1238.
18. 汪珍光, 傅思源, 周伟平, 等.逆行右半肝联合全尾状叶肿瘤切除术.中华消化外科杂志, 2013, 12(9):655-658.
19. Nanashima A, Tobinaga S, Abo T, et al. Left hepatectomy accompanied by a resection of the whole caudate lobe using the dorsally fixed liver-hanging maneuver. Surg Today, 2011, 41(3):453-458.
20. Oya H, Sato Y, Yamamoto S, et al. A new technique of lateral approach for laparoscopy-assisted donor left hepatectomy. Hepatogastroenterology, 2011, 58(110-111):1765-1768.
21. 匡铭, 汤地, 王晔, 等.三维手术模拟系统在肝癌患者精准肝切除中的应用.中国普外基础与临床杂志, 2011, 18(7):682-687.
22. 皮勇, 谢飞, 寇丽.尾状叶与非尾状叶肝癌手术切除疗效对比观察.安徽医药, 2014, 18(9):1686-1689.
23. 娄尧强, 江献川, 彭淑牖, 等.肝脏恶性肿瘤682例手术治疗分析.中华外科杂志, 2004, 42(9):513-516.
24. 王培培, 王军, 齐曼, 等.直肠癌术后三维适形/调强放疗联合化疗与单纯辅助化疗的疗效比较.肿瘤防治研究, 2014, 45(5):468-473.
25. Jones RM, Moulton CE, Hardy KJ. Central venous pressure and its effect on blood loss during liver resection. Br J Surg, 1998, 85(8):1058-1060.
26. 彭淑牖, 刘颖斌, 许斌, 等.肝静脉和下腔静脉血流控制在高难度肝肿瘤切除中的应用.中华外科杂志, 2004, 42(5):260-264.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Surgical Treatment of Malignant Tumors at Caudate Lobe of Liver in 51 Cases

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