关于乳腺癌根治术后局部复发的一点思考（附1例报道）_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

 罗妍 ,  周平

中国人民解放军空军总医院肿瘤放疗科（北京 100142）;

Corresponding author：

周平, Email: zhouping4946@163.com

Keywords：

乳腺癌; 局部复发; 治疗; 文献复习

DOI：

10.7507/1007-9424.20150193

Video：

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Abstract Full text Figures/Tables Video References Cited by

目的探讨乳腺癌根治术后局部复发治疗方法的选择。方法回顾性分析中国人民解放军空军总医院收治的1例乳腺癌根治术后局部复发患者的临床资料，并进行文献复习。结果本例患者行左乳腺癌改良根治术后8年出现复发并转移，接受“化疗-放疗-化疗”综合治疗后，取得了良好的治疗效果，复查胸部CT检查示术区未见异常软组织影及肿瘤复发。结论有多种因素影响乳腺癌局部复发患者治疗方法的选择，通过制定个体化治疗方案，可以局部控制局部复发乳腺癌，并减少肿瘤的远处转移，提高患者的生存率。

Citation： 罗妍, 周平. 关于乳腺癌根治术后局部复发的一点思考（附1例报道）. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2015, 22(6): 740-741. doi: 10.7507/1007-9424.20150193 Copy

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2.	Pierce LJ. The use of radiotherapy after mastectomy:a review of the literature. J Clin Oncol, 2005, 23(8):1706-1717.
3.	Pennery E. The role of endocrine therapies in reducing risk of recurrence in postmenopausal women with hormone receptor-positive breast cancer. Eur J Oncol Nurs, 2008, 12(3):233-243.
4.	Fodor J, Major T, Polgár C, et al. Prognosis of patients with local recurrence after mastectomy or conservative surgery for early-stage invasive breast cancer. Breast, 2008, 17(3):302-308.
5.	Dinh P, Cardoso F, Sotiriou C, et al. New tools for assessing breast cancer recurrence. Cancer Treat Res, 2008, 141:99-118.
6.	Brewster AM, Do KA, Thompson PA, et al. Relationship between epidemiologic risk factors and breast cancer recurrence. J Clin Oncol, 2007, 25(28):4438-4444.
7.	Paepke S, Jacobs VR, Ohlinger R, et al. Treatment strategies that effectively reduce early recurrence risk in postmenopausal women with endocrine-sensitive breast cancer:AIs upfront vs. switching. J Cancer Res Clin Oncol, 2007, 133(12):905-916.
8.	Pisansky TM, Ingle JN, Schaid DJ, et al. Patterns of tumor relapse following mastectomy and adjuvant systemic therapy in patients with axillary lymph node-positive breast cancer. Impact of clinical, histopathologic, and flow cytometric factors. Cancer, 1993, 72(4):1247-1260.
9.	Wenger CR, Clark GM. S-phase fraction and breast cancer-a decade of experience. Breast Cancer Res Treat, 1998, 51(3):255-265.
10.	Halverson KJ, Perez CA, Kuske RR, et al. Locoregional recurrence of breast cancer:a retrospective comparison of irradiation alone versus irradiation and systemic therapy. Am J Clin Oncol, 1992, 15(2):93-101.
11.	陈佳艺, 郭小毛, 章真, 等.影响乳腺癌根治术后局部-区域性复发放射治疗后局部控制的因素.中华放射肿瘤学杂志, 2008, 17(1):11-16.
12.	陈佳艺, 冯炎.乳腺癌术后胸壁复发的放射治疗.中华放射肿瘤学杂志, 2004, 13(3):196-200.
13.	Hannoun-Levi JM, Houvenaeghel G, Ellis S, et al. Partial breast irradiation as second conservative treatment for local breast cancer recurrence. Int J Radiat Oncol Biol Phys, 2004, 60(5):1385-1392.
14.	王晓庆, 张晟, 刘艳, 等.乳腺癌术后局部复发的治疗及预后分析.中华普通外科杂志, 2011, 26(6):489-492.

1. Katz A, Strom EA, Buchholz TA, et al. Locoregional recurrence patterns after mastectomy and doxorubicin-based chemotherapy:implications for postoperative irradiation. J Clin Oncol, 2000, 18 (15):2817-2827.
2. Pierce LJ. The use of radiotherapy after mastectomy:a review of the literature. J Clin Oncol, 2005, 23(8):1706-1717.
3. Pennery E. The role of endocrine therapies in reducing risk of recurrence in postmenopausal women with hormone receptor-positive breast cancer. Eur J Oncol Nurs, 2008, 12(3):233-243.
4. Fodor J, Major T, Polgár C, et al. Prognosis of patients with local recurrence after mastectomy or conservative surgery for early-stage invasive breast cancer. Breast, 2008, 17(3):302-308.
5. Dinh P, Cardoso F, Sotiriou C, et al. New tools for assessing breast cancer recurrence. Cancer Treat Res, 2008, 141:99-118.
6. Brewster AM, Do KA, Thompson PA, et al. Relationship between epidemiologic risk factors and breast cancer recurrence. J Clin Oncol, 2007, 25(28):4438-4444.
7. Paepke S, Jacobs VR, Ohlinger R, et al. Treatment strategies that effectively reduce early recurrence risk in postmenopausal women with endocrine-sensitive breast cancer:AIs upfront vs. switching. J Cancer Res Clin Oncol, 2007, 133(12):905-916.
8. Pisansky TM, Ingle JN, Schaid DJ, et al. Patterns of tumor relapse following mastectomy and adjuvant systemic therapy in patients with axillary lymph node-positive breast cancer. Impact of clinical, histopathologic, and flow cytometric factors. Cancer, 1993, 72(4):1247-1260.
9. Wenger CR, Clark GM. S-phase fraction and breast cancer-a decade of experience. Breast Cancer Res Treat, 1998, 51(3):255-265.
10. Halverson KJ, Perez CA, Kuske RR, et al. Locoregional recurrence of breast cancer:a retrospective comparison of irradiation alone versus irradiation and systemic therapy. Am J Clin Oncol, 1992, 15(2):93-101.
11. 陈佳艺, 郭小毛, 章真, 等.影响乳腺癌根治术后局部-区域性复发放射治疗后局部控制的因素.中华放射肿瘤学杂志, 2008, 17(1):11-16.
12. 陈佳艺, 冯炎.乳腺癌术后胸壁复发的放射治疗.中华放射肿瘤学杂志, 2004, 13(3):196-200.
13. Hannoun-Levi JM, Houvenaeghel G, Ellis S, et al. Partial breast irradiation as second conservative treatment for local breast cancer recurrence. Int J Radiat Oncol Biol Phys, 2004, 60(5):1385-1392.
14. 王晓庆, 张晟, 刘艳, 等.乳腺癌术后局部复发的治疗及预后分析.中华普通外科杂志, 2011, 26(6):489-492.

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CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

关于乳腺癌根治术后局部复发的一点思考（附1例报道）

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