• 1. Department of Thyroid Surgery, Affiliated Hospital of Guizhou Medical University, Guiyang 550004, Guizhou Province, China;
  • 2. Guizhou Medical University, Guiyang 550004, Guizhou Province, China;
  • 3. Department of Thyroid Surgery, Second Affiliated Hospital of Guizhou Medical University, Kaili 556000, Guizhou Province, China;
ZHAODai-wei, Email: zhaodw@hotmail.com
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Objective To summarize the domestic and abroad articles related to the research on the relation between miRNA-221/222 and thyroid cancer, and explore the important effects of miRNA-221/222 in diagnosis and treatment of thyroid cancer. Methods Domestic and international publications involving the relationship of miRNA-221/222 to thyroid cancer were screened and reviewed. Results MiRNA-221/222 is a tumor marker with high specificity and sensitivity in thyroid cancer. It has important significance for diagnosis, treatment and prognosis of thyroid cancer. Conclusion MiRNA-221/222 is not only related to diagnosis of thyroid cancer, but also have provided a new research direction and method for gene therapy of thyroid cancer.

Citation: WANGYun-sheng, GAOQing-jun, ZHAODai-wei. Function of MiRNA-221/222 in Thyroid Cance. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2016, 23(7): 887-890. doi: 10.7507/1007-9424.20160232 Copy

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