肿瘤大小对各T分期胃癌患者预后影响的分析_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

 李小宝 ¹ , 姬乐 ¹ , 曹波 ¹ , 黄江 ¹ , 刘勇峰 ¹ , 白铁成 ¹ , 梅乐园 ¹ , 车向明 ²

1. ;
2. ;

Corresponding author：

李小宝, Email: lixiaobao2007@126.com

Keywords：

胃癌; 肿瘤大小; T分期; 预后

DOI：

10.7507/1007-9424.20160323

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

目的探讨肿瘤大小对各T分期胃癌患者预后的影响。方法收集535例行根治术胃癌患者的临床资料，采用ROC曲线下面积取截断点，根据肿瘤直径分为＜4.5 cm组和≥4.5 cm组。应用Kaplan-Meier生存曲线比较相同T分期中不同肿瘤大小对胃癌患者预后的影响。结果肿瘤直径＜4.5 cm组和≥4.5 cm组患者术后5年累积生存率分别为66.9%和28.3%，其差异有统计学意义（P＜0.05）。在T1期患者中，肿瘤直径≥4.5 cm组与＜4.5 cm组之间预后差异无统计学意义（P＞0.05）；在T2及T3期患者中，肿瘤直径≥4.5 cm组和＜4.5 cm组之间预后差异有统计学意义（P＜0.05）；在T4期患者中，肿瘤直径≥4.5 cm组和＜4.5 cm组之间预后差异无统计学意义（P＞0.05）。结论肿瘤大小是影响T2及T3期胃癌患者预后的重要因素之一。

Citation： 李小宝, 姬乐, 曹波, 黄江, 刘勇峰, 白铁成, 梅乐园, 车向明. 肿瘤大小对各T分期胃癌患者预后影响的分析. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2016, 23(10): 1262-1264. doi: 10.7507/1007-9424.20160323 Copy

1.	Jemal A, Bray F, Center MM, et al. Global cancer statistics. CA Cancer J Clin, 2011, 61(2):69-90.
2.	Saito H, Fukumoto Y, Osaki T, et al. Prognostic signifcance of level and number of lymph node metastases in patients with gastric cancer. Ann Surg Oncol, 2007, 14(5):1688-1693.
3.	Liu X, Xu Y, Long Z, et al. Prognostic significance of tumor size in T3 gastric cancer. Ann Surg Oncol, 2009, 16(7):1875-1882.
4.	Japanese Gastric Cancer Association. Janpanese classification of gastric carcinoma:3rd English edition. Gastric Cancer, 2011, 14(2):101-112.
5.	Yokota T, Ishiyama S, Saito T, et al. Is tumor size a prognostic indicator for gastric carcinoma? Anticancer Res, 2002, 22(6B):3673-3677.
6.	Im WJ, Kim MG, Ha TK, et al. Tumor size as a prognostic factor in gastric cancer patient. J Gastric Cancer, 2012, 12(3):164-172.
7.	Mohri Y, Tanaka K, Ohi M, et al. Prognostic significance of host- and tumor-related factors in patients with gastric cancer. World J Surg, 2010, 34(2):285-290.
8.	张梅玲,王建,施伟,等. 肿瘤直径对胃癌患者预后判断价值的分析. 南京医科大学学报:自然科学版,2011, 31(2):229-234.
9.	Lu J, Huang CM, Zheng CH, et al. Prognostic value of tumor size in patients with remnant gastric cancer:is the seventh UICC stage sufficient for predicting prognosis? PLoS One, 2014, 9(12):e115776.
10.	Li XB, Cao B, Mei LY, et al. Mulitivariate analysis of prognostic factors in 549 patients undergoing surgical treatment of gastric cancer. Hepatogastroenterology, 2014, 130(61):535-542.
11.	Li C, Oh SJ, Kim S, et al. Risk factors of survival and surgical treatment for advanced gastric cancer with large tumor size. J Gastrointest Surg, 2009, 13(5):881-885.
12.	Kikuchi S, Katada N, Sakuramoto S, et al. Survival after surgical treatment of early gastric cancer:surgical techniques and long term survival. Langenbecks Arch Surg, 2004, 389(2):69-74.
13.	Zu H, Wang F, Ma Y, et al. Stage-stratified analysis of prognostic significance of tumor size in patients with gastric cancer. PLoS One, 2013, 8(1):e54502.
14.	Huang CM, Xu M, Wang JB, et al. Is tumor size a predictor of preoperative N staging in T2-T4a stage advanced gastric cancer? Surg Oncol, 2014,23(1):5-10.
15.	Hyung WJ, Noh SH, Yoo CH, et al. Prognostic significance of metastatic lymph node ration in T3 gastric cancer. World J Surg, 2002, 26(3):323-329.
16.	Wang HM, Huang CM, Zheng CH, et al. Tumor size as a prognostic factor in patients with advanced gastric cancer in the lower third of the stomach. World J Gastroenterol, 2012, 18(38):5470-5475.

1. Jemal A, Bray F, Center MM, et al. Global cancer statistics. CA Cancer J Clin, 2011, 61(2):69-90.
2. Saito H, Fukumoto Y, Osaki T, et al. Prognostic signifcance of level and number of lymph node metastases in patients with gastric cancer. Ann Surg Oncol, 2007, 14(5):1688-1693.
3. Liu X, Xu Y, Long Z, et al. Prognostic significance of tumor size in T3 gastric cancer. Ann Surg Oncol, 2009, 16(7):1875-1882.
4. Japanese Gastric Cancer Association. Janpanese classification of gastric carcinoma:3rd English edition. Gastric Cancer, 2011, 14(2):101-112.
5. Yokota T, Ishiyama S, Saito T, et al. Is tumor size a prognostic indicator for gastric carcinoma? Anticancer Res, 2002, 22(6B):3673-3677.
6. Im WJ, Kim MG, Ha TK, et al. Tumor size as a prognostic factor in gastric cancer patient. J Gastric Cancer, 2012, 12(3):164-172.
7. Mohri Y, Tanaka K, Ohi M, et al. Prognostic significance of host- and tumor-related factors in patients with gastric cancer. World J Surg, 2010, 34(2):285-290.
8. 张梅玲,王建,施伟,等. 肿瘤直径对胃癌患者预后判断价值的分析. 南京医科大学学报:自然科学版,2011, 31(2):229-234.
9. Lu J, Huang CM, Zheng CH, et al. Prognostic value of tumor size in patients with remnant gastric cancer:is the seventh UICC stage sufficient for predicting prognosis? PLoS One, 2014, 9(12):e115776.
10. Li XB, Cao B, Mei LY, et al. Mulitivariate analysis of prognostic factors in 549 patients undergoing surgical treatment of gastric cancer. Hepatogastroenterology, 2014, 130(61):535-542.
11. Li C, Oh SJ, Kim S, et al. Risk factors of survival and surgical treatment for advanced gastric cancer with large tumor size. J Gastrointest Surg, 2009, 13(5):881-885.
12. Kikuchi S, Katada N, Sakuramoto S, et al. Survival after surgical treatment of early gastric cancer:surgical techniques and long term survival. Langenbecks Arch Surg, 2004, 389(2):69-74.
13. Zu H, Wang F, Ma Y, et al. Stage-stratified analysis of prognostic significance of tumor size in patients with gastric cancer. PLoS One, 2013, 8(1):e54502.
14. Huang CM, Xu M, Wang JB, et al. Is tumor size a predictor of preoperative N staging in T2-T4a stage advanced gastric cancer? Surg Oncol, 2014,23(1):5-10.
15. Hyung WJ, Noh SH, Yoo CH, et al. Prognostic significance of metastatic lymph node ration in T3 gastric cancer. World J Surg, 2002, 26(3):323-329.
16. Wang HM, Huang CM, Zheng CH, et al. Tumor size as a prognostic factor in patients with advanced gastric cancer in the lower third of the stomach. World J Gastroenterol, 2012, 18(38):5470-5475.

Previous Article
腹腔镜手术对中低位直肠癌患者免疫功能和切口感染的影响
Next Article
腹腔镜胆囊切除术意外胆囊癌22例报道

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

肿瘤大小对各T分期胃癌患者预后影响的分析

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content