• 1. Shaanxi University of Chinese Medicine, Xianyang, Shaanxi 712046, P. R. China;
  • 2. Department of General Surgery, Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi 712000, P. R. China;
ZHOU Jun, Email: 13629106789@163.com
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Objective To analyze risk factors of rebleeding after laparoscopic selective pericardial devascularization combined with splenectomy.Methods The clinical data of 147 cases of portal hypertension treated by the laparoscopic selective devascularization combined with splenectomy from February 2014 to September 2018 were retrospectively analyzed. The univariate analysis was used to find the difference between the rebleeding group (n=20) and the non-bleeding group (n=127), then the multivariate logistic regression analysis was selected for screening out the most closely related risk factors for the rebleeding.Results The rebleeding occurred in 20 of 147 patients (13.6%). There were differences in the platelet count, prothrombin time, serum albumin, diameter of main portal vein, classification of liver function, ascites, hepatic encephalopathy, and portal hypertensive gastropathy between the rebleeding group and the non-bleeding group (P<0.050). The classification of liver function [OR=3.444, 95% CI (1.211. 9.793), P=0.020], ascites [OR=2.859, 95% CI (1.069, 7.645), P=0.036], hepatic encephalopathy [OR=4.265, 95% CI(1.121, 16.230), P=0.033], and portal hypertensive gastropathy [OR=6.744, 95% CI (1.675, 27.156), P=0.007], and platelet count [OR=4.744, 95% CI (1.073, 20.969), P=0.040] were the independent factors for the postoperative rebleeding by the logistic regression analysis.Conclusion For patients with risk factors of rebleeding, preoperative treatment should be actively taken and postoperative prevention of rebleeding should be highly vigilant.

Citation: ZHANG Kang, ZHOU Jun, LEI Ting, JIA Zipei. Multivariate regression analysis of rebleeding related factors after laparoscopic selective pericardial devascularization combined with splenectomy. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2019, 26(7): 798-802. doi: 10.7507/1007-9424.201902061 Copy

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