WU Zhiyuan 1 , ZHAO Wenxin 1,2 , MIAO Yuqing 1,2 , LI Zhichao 1,3 , ZHANG Xihao 1,3 , LI Ruihao 1,2 , CHEN Zuoguan 1 , DIAO Yongpeng 1 , LAN Yong 1,2 , LI Yongjun 1,2,3
  • 1. Department of Vascular Surgery, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, P. R. China;
  • 2. Chinese Academy of Medical Sciences, Peking Union Medical College Graduate School, Beijing 100730, P. R. China;
  • 3. Peking University Health Science Center, Beijing 100191, P. R. China;
LI Yongjun, Email: liyongjun4679@bjhmoh.cn
abdominal aortic aneurysm; Neutrophil-to-lymphocyte ratio; endovascular repair; postoperative complication; forecast
10.7507/1007-9424.202211002
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Objective  To explore the predictive value of neutrophil-to-lymphocyte ratio (NLR) in peripheral blood for postoperative complications of elective endovascular repair for abdominal aortic aneurysm (AAA). Methods  From August 2016 to November 2021, the clinical data of patients with AAA who received endovascular isolation repair for the first time in the Department of Vascular Surgery of Beijing Hospital were retrospectively analyzed, including the basic information of the patients, comorbid diseases, and the largest diameter of AAA, preoperative blood labotry test, postoperative complications, long-term survival rate and other indicators. The optimal NLR in peripheral blood was determined, and the differences in postoperative complications and long-term survival rates between the high NLR group and the low NLR group were analysed. Results  A total of 120 patients with AAA underwent endovascular isolation for the first time were included in this study, including 105 males and 15 females. The age ranged from 52 to 94 years, with an average of (73.3 ± 8.26) years. The largest diameter of abdominal aortic aneurysm was 35 to 100 mm, with an average of (58.5 ± 12.48) mm. The best cut-off value of NLR for predicting postoperative complications of AAA was 2.45 by using Yoden index screening. Those with NLR ≥2.45 were in the high NLR group (n=66), and those with NLR <2.45 were in the low NLR group (n=54). There was no statistically significant difference between the two groups in the incidence of overall complications and the incidence of sub-complications (P>0.05). The results of logistic regression analysis suggested that NLR was an independent risk factor for complications after endovascular repair of AAA (P<0.05). The median survival time of patients in the high NLR group and the low NLR group was 31.47 months and 35.28 months, respectively, and there was no statistically significant difference between the two groups (P>0.05). Conclusion  NLR can be used as a reference predictor of complications after elective endovascular repair of AAA, but more research results are still needed to confirm.

Citation： WU Zhiyuan, ZHAO Wenxin, MIAO Yuqing, LI Zhichao, ZHANG Xihao, LI Ruihao, CHEN Zuoguan, DIAO Yongpeng, LAN Yong, LI Yongjun. Predictive value of the neutrophil-to-lymphocyte ratio in peripheral blood for complications after elective endovascular repair of abdominal aortic aneurysm. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2023, 30(6): 703-708. doi: 10.7507/1007-9424.202211002 Copy

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