Imaging diagnosis of non<b>-</b>tumor diseases of gallbladder_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

CHEN Zhixia , ZHANG Dian , CHEN Weixia ,  LU Chunyan

1. Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, P. R. China;

Corresponding author：

LU Chunyan, Email: luchunyan@wchscu.cn

Keywords：

non-tumor diseases of gallbladder; gallbladder stones; cholecystitis; gallbladder polyps; gallbladder adenomyomatosis; imaging signs

DOI：

10.7507/1007-9424.202401048

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

With the development and popularization of imaging technology, the discovery of gallbladder lesions has become common, among which non-neoplastic lesions (such as gallbladder stones, cholecystitis, gallbladder polyps, gallbladder adenomyosis, etc.) are common but sometimes the imaging manifestations are not specific, and there are many kinds of such diseases, so accurate imaging diagnosis is still quite challenging. Familiarity and understanding of the typical imaging manifestations of these diseases will help to improve the early and accurate diagnosis and help to distinguish them from gallbladder malignant diseases, which is of great significance to the diagnosis, guiding treatment and prognosis of patients.

Citation： CHEN Zhixia, ZHANG Dian, CHEN Weixia, LU Chunyan. Imaging diagnosis of non-tumor diseases of gallbladder. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2024, 31(3): 278-284. doi: 10.7507/1007-9424.202401048 Copy

1.	Chatterjee A, Lopes Vendrami C, Nikolaidis P, et al. Uncommon intraluminal tumors of the gallbladder and biliary tract: spectrum of imaging appearances. Radiographics, 2019, 39(2): 388-412.
2.	Lim J H, Jang K T, Kim J H. Neoplasms of the biliary tract: radiologic and pathologic correlations. Singapore: Springer Singapore, 2021: 4-5.
3.	Lopes Vendrami C, Magnetta MJ, Mittal PK, et al. Gallbladder carcinoma and its differential diagnosis at MRI: What radiologists should know. Radiographics, 2021, 41(1): 78-95.
4.	Bazira PJ. Anatomy of the gallbladder and bile ducts. Surgery (Oxford), 2023, 41(6): 319-324.
5.	Gupta P, Kumar M, Sharma V, et al. Evaluation of gallbladder wall thickening: a multimodality imaging approach. Expert Rev Gastroenterol Hepatol, 2020, 14(6): 463-473.
6.	Gupta P, Marodia Y, Bansal A, et al. Imaging-based algorithmic approach to gallbladder wall thickening. World J Gastroenterol, 2020, 26(40): 6163-6181.
7.	Klimkowski SP, Fung A, Menias CO, et al. Gallbladder imaging interpretation pearls and pitfalls: ultrasound, computed tomography, and magnetic resonance imaging. Radiol Clin North Am, 2022, 60(5): 809-824.
8.	Lammert F, Gurusamy K, Ko CW, et al. Gallstones. Nat Rev Dis Primers, 2016, 2: 16024.
9.	Bortoff GA, Chen MY, Ott DJ, et al. Gallbladder stones: imaging and intervention. Radiographics, 2000, 20(3): 751-766.
10.	Yu MH, Kim YJ, Park HS, et al. Benign gallbladder diseases: Imaging techniques and tips for differentiating with malignant gallbladder diseases. World J Gastroenterol, 2020, 26(22): 2967-2986.
11.	Ratanaprasatporn L, Uyeda JW, Wortman JR, et al. Multimodality imaging, including dual-energy CT, in the evaluation of gallbladder disease. Radiographics, 2018, 38(1): 75-89.
12.	Gandhi D, Ojili V, Nepal P, et al. A pictorial review of gall stones and its associated complications. Clin Imaging, 2020, 60(2): 228-236.
13.	Cao Z, Wei J, Zhang N, Liu W, et al. Risk factors of systematic biliary complications in patients with gallbladder stones. Ir J Med Sci, 2020, 189(3): 943-947.
14.	索运生, 肖宏, 尹思能. 胆囊十二指肠瘘的腹腔镜治疗. 中国普外基础与临床杂志, 2008, 15(11): 847-848.
15.	Middleton WD, Fung C, Dahiya N, et al. Survey study on the experience, practice patterns, and preferences of the fellows of the society of radiologists in ultrasound for evaluation and management of gallbladder polyps detected with ultrasound. Ultrasound Q, 2022, 38(2): 96-102.
16.	Szpakowski JL, Tucker LY. Outcomes of gallbladder polyps and their association with gallbladder cancer in a 20-year cohort. JAMA Netw Open, 2020, 3(5): e205143.
17.	Liu K, Lin N, You Y, et al. Risk factors to discriminate neoplastic polypoid lesions of gallbladder: A large-scale case-series study. Asian J Surg, 2021, 44(12): 1515-1519.
18.	Konstantinoff KS, Feister KF, Mellnick VM. RadioGraphics update: new follow-up and management recommendations for polypoid lesions of the gallbladder. Radiographics, 2023, 43(3): e220189.
19.	Dursun N, Memis B, Pehlivanoglu B, et al. Adenomyomas of the gallbladder: an analysis of frequency, clinicopathologic associations, and relationship to carcinoma of a malformative lesion. Arch Pathol Lab Med, 2024, 148(2): 206-214.
20.	Pang L, Zhang Y, Wang Y, et al. Pathogenesis of gallbladder adenomyomatosis and its relationship with early-stage gallbladder carcinoma: an overview. Braz J Med Biol Res, 2018, 51(6): e7411.
21.	Mellnick VM, Menias CO, Sandrasegaran K, et al. Polypoid lesions of the gallbladder: disease spectrum with pathologic correlation. Radiographics, 2015, 35(2): 387-399.
22.	Riddell ZC, Corallo C, Albazaz R, et al. Gallbladder polyps and adenomyomatosis. Br J Radiol, 2023, 96(1142): 20220115.
23.	Bonde AA, Virarkar M, Zahid M, et al. Imaging update on gallbladder adenomyomatosis and its mimics. Clin Imaging, 2024, 105: 109997.
24.	Yang HK, Lee JM, Yu MH, et al. CT diagnosis of gallbladder adenomyomatosis: importance of enhancing mucosal epithelium, the “cotton ball sign”. Eur Radiol, 2018, 28(9): 3573-3582.
25.	Gallaher JR, Charles A. Acute cholecystitis: a review. JAMA, 2022, 327(10): 965-975.
26.	Tran A, Hoff C, Polireddy K, et al. Beyond acute cholecystitis-gallstone-related complications and what the emergency radiologist should know. Emerg Radiol, 2022, 29(1): 173-186.
27.	Maddu K, Phadke S, Hoff C. Complications of cholecystitis: a comprehensive contemporary imaging review. Emerg Radiol, 2021, 28(5): 1011-1027.
28.	Clemente G, Nuzzo G, De Rose AM, et al. Unexpected gallbladder cancer after laparoscopic cholecystectomy for acute cholecystitis: a worrisome picture. J Gastrointest Surg, 2012, 16(8): 1462-1468.
29.	Catalano OA, Sahani DV, Kalva SP, et al. MR imaging of the gallbladder: a pictorial essay. Radiographics, 2008, 28(1): 135-155.
30.	Guzmán-Valdivia G. Xanthogranulomatous cholecystitis: 15 years’ experience. World J Surg, 2004, 28(3): 254-257.
31.	Runde R, Auyang ED, Ng R, et al. The gallbladder: what’s new in 2022? Abdom Radiol (NY), 2023, 48(1): 2-28.
32.	Ichikawa S, Oishi N, Kondo T, et al. Key imaging findings for the prospective diagnosis of rare diseases of the gallbladder and cystic duct. Korean J Radiol, 2021, 22(9): 1462-1474.
33.	Huang EY, Reeves JJ, Broderick RC, et al. Distinguishing characteristics of xanthogranulomatous cholecystitis and gallbladder adenocarcinoma: a persistent diagnostic dilemma. Surg Endosc, 2024, 38(1): 348-355.
34.	Makimoto S, Takami T, Hatano K, et al. Xanthogranulomatous cholecystitis: a review of 31 patients. Surg Endosc, 2021, 35(7): 3874-3880.
35.	Goshima S, Chang S, Wang JH, et al. Xanthogranulomatous cholecystitis: diagnostic performance of CT to differentiate from gallbladder cancer. Eur J Radiol, 2010, 74(3): e79-e83.
36.	Wu S, Wang H. IgG4-related digestive diseases: diagnosis and treatment. Front Immunol, 2023, 14: 1278332.
37.	Harada Y, Mihara K, Amemiya R, et al. Isolated IgG4-related cholecystitis with localized gallbladder wall thickening mimicking gallbladder cancer: a case report and literature review. BMC Gastroenterol, 2022, 22(1): 99.
38.	Watanabe K, Kamisawa T, Chiba K, et al. Gallbladder wall thickening in patients with IgG4-related diseases, with special emphasis on IgG4-related cholecystitis. Scand J Gastroenterol, 2021, 56(12): 1456-1461.
39.	Kuwatani M, Sakamoto N. Clinical and image characteristics of IgG4-related sclerosing cholecystitis. Diagnostics (Basel), 2021, 11(8): 1358.
40.	Son JY, Kim YJ, Park HS, et al. Diffuse gallbladder wall thickening on computed tomography in patients with liver cirrhosis: correlation with clinical and laboratory variables. J Comput Assist Tomogr, 2011, 35(5): 535-538.
41.	Bremer SCB, Knoop RF, Porsche M, et al. Pathological gallbladder wall thickening is associated with advanced chronic liver disease and independent of serum albumin. J Clin Ultrasound, 2022, 50(3): 367-374.
42.	Liu Y, Wang K, Liu H. Gallbladder tuberculosis mimicking gallbladder carcinoma: A case report and literature review. Case Reports Hepatol, 2016, 2016: 3629708.
43.	Xu XF, Yu RS, Qiu LL, et al. Gallbladder tuberculosis: CT findings with histopathologic correlation. Korean J Radiol, 2011, 12(2): 196-202.
44.	Lee YH, Kim SH, Cho MY, et al. Actinomycosis of the gallbladder mimicking carcinoma: a case report with US and CT findings. Korean J Radiol, 2007, 8(2): 169-172.

1. Chatterjee A, Lopes Vendrami C, Nikolaidis P, et al. Uncommon intraluminal tumors of the gallbladder and biliary tract: spectrum of imaging appearances. Radiographics, 2019, 39(2): 388-412.
2. Lim J H, Jang K T, Kim J H. Neoplasms of the biliary tract: radiologic and pathologic correlations. Singapore: Springer Singapore, 2021: 4-5.
3. Lopes Vendrami C, Magnetta MJ, Mittal PK, et al. Gallbladder carcinoma and its differential diagnosis at MRI: What radiologists should know. Radiographics, 2021, 41(1): 78-95.
4. Bazira PJ. Anatomy of the gallbladder and bile ducts. Surgery (Oxford), 2023, 41(6): 319-324.
5. Gupta P, Kumar M, Sharma V, et al. Evaluation of gallbladder wall thickening: a multimodality imaging approach. Expert Rev Gastroenterol Hepatol, 2020, 14(6): 463-473.
6. Gupta P, Marodia Y, Bansal A, et al. Imaging-based algorithmic approach to gallbladder wall thickening. World J Gastroenterol, 2020, 26(40): 6163-6181.
7. Klimkowski SP, Fung A, Menias CO, et al. Gallbladder imaging interpretation pearls and pitfalls: ultrasound, computed tomography, and magnetic resonance imaging. Radiol Clin North Am, 2022, 60(5): 809-824.
8. Lammert F, Gurusamy K, Ko CW, et al. Gallstones. Nat Rev Dis Primers, 2016, 2: 16024.
9. Bortoff GA, Chen MY, Ott DJ, et al. Gallbladder stones: imaging and intervention. Radiographics, 2000, 20(3): 751-766.
10. Yu MH, Kim YJ, Park HS, et al. Benign gallbladder diseases: Imaging techniques and tips for differentiating with malignant gallbladder diseases. World J Gastroenterol, 2020, 26(22): 2967-2986.
11. Ratanaprasatporn L, Uyeda JW, Wortman JR, et al. Multimodality imaging, including dual-energy CT, in the evaluation of gallbladder disease. Radiographics, 2018, 38(1): 75-89.
12. Gandhi D, Ojili V, Nepal P, et al. A pictorial review of gall stones and its associated complications. Clin Imaging, 2020, 60(2): 228-236.
13. Cao Z, Wei J, Zhang N, Liu W, et al. Risk factors of systematic biliary complications in patients with gallbladder stones. Ir J Med Sci, 2020, 189(3): 943-947.
14. 索运生, 肖宏, 尹思能. 胆囊十二指肠瘘的腹腔镜治疗. 中国普外基础与临床杂志, 2008, 15(11): 847-848.
15. Middleton WD, Fung C, Dahiya N, et al. Survey study on the experience, practice patterns, and preferences of the fellows of the society of radiologists in ultrasound for evaluation and management of gallbladder polyps detected with ultrasound. Ultrasound Q, 2022, 38(2): 96-102.
16. Szpakowski JL, Tucker LY. Outcomes of gallbladder polyps and their association with gallbladder cancer in a 20-year cohort. JAMA Netw Open, 2020, 3(5): e205143.
17. Liu K, Lin N, You Y, et al. Risk factors to discriminate neoplastic polypoid lesions of gallbladder: A large-scale case-series study. Asian J Surg, 2021, 44(12): 1515-1519.
18. Konstantinoff KS, Feister KF, Mellnick VM. RadioGraphics update: new follow-up and management recommendations for polypoid lesions of the gallbladder. Radiographics, 2023, 43(3): e220189.
19. Dursun N, Memis B, Pehlivanoglu B, et al. Adenomyomas of the gallbladder: an analysis of frequency, clinicopathologic associations, and relationship to carcinoma of a malformative lesion. Arch Pathol Lab Med, 2024, 148(2): 206-214.
20. Pang L, Zhang Y, Wang Y, et al. Pathogenesis of gallbladder adenomyomatosis and its relationship with early-stage gallbladder carcinoma: an overview. Braz J Med Biol Res, 2018, 51(6): e7411.
21. Mellnick VM, Menias CO, Sandrasegaran K, et al. Polypoid lesions of the gallbladder: disease spectrum with pathologic correlation. Radiographics, 2015, 35(2): 387-399.
22. Riddell ZC, Corallo C, Albazaz R, et al. Gallbladder polyps and adenomyomatosis. Br J Radiol, 2023, 96(1142): 20220115.
23. Bonde AA, Virarkar M, Zahid M, et al. Imaging update on gallbladder adenomyomatosis and its mimics. Clin Imaging, 2024, 105: 109997.
24. Yang HK, Lee JM, Yu MH, et al. CT diagnosis of gallbladder adenomyomatosis: importance of enhancing mucosal epithelium, the “cotton ball sign”. Eur Radiol, 2018, 28(9): 3573-3582.
25. Gallaher JR, Charles A. Acute cholecystitis: a review. JAMA, 2022, 327(10): 965-975.
26. Tran A, Hoff C, Polireddy K, et al. Beyond acute cholecystitis-gallstone-related complications and what the emergency radiologist should know. Emerg Radiol, 2022, 29(1): 173-186.
27. Maddu K, Phadke S, Hoff C. Complications of cholecystitis: a comprehensive contemporary imaging review. Emerg Radiol, 2021, 28(5): 1011-1027.
28. Clemente G, Nuzzo G, De Rose AM, et al. Unexpected gallbladder cancer after laparoscopic cholecystectomy for acute cholecystitis: a worrisome picture. J Gastrointest Surg, 2012, 16(8): 1462-1468.
29. Catalano OA, Sahani DV, Kalva SP, et al. MR imaging of the gallbladder: a pictorial essay. Radiographics, 2008, 28(1): 135-155.
30. Guzmán-Valdivia G. Xanthogranulomatous cholecystitis: 15 years’ experience. World J Surg, 2004, 28(3): 254-257.
31. Runde R, Auyang ED, Ng R, et al. The gallbladder: what’s new in 2022? Abdom Radiol (NY), 2023, 48(1): 2-28.
32. Ichikawa S, Oishi N, Kondo T, et al. Key imaging findings for the prospective diagnosis of rare diseases of the gallbladder and cystic duct. Korean J Radiol, 2021, 22(9): 1462-1474.
33. Huang EY, Reeves JJ, Broderick RC, et al. Distinguishing characteristics of xanthogranulomatous cholecystitis and gallbladder adenocarcinoma: a persistent diagnostic dilemma. Surg Endosc, 2024, 38(1): 348-355.
34. Makimoto S, Takami T, Hatano K, et al. Xanthogranulomatous cholecystitis: a review of 31 patients. Surg Endosc, 2021, 35(7): 3874-3880.
35. Goshima S, Chang S, Wang JH, et al. Xanthogranulomatous cholecystitis: diagnostic performance of CT to differentiate from gallbladder cancer. Eur J Radiol, 2010, 74(3): e79-e83.
36. Wu S, Wang H. IgG4-related digestive diseases: diagnosis and treatment. Front Immunol, 2023, 14: 1278332.
37. Harada Y, Mihara K, Amemiya R, et al. Isolated IgG4-related cholecystitis with localized gallbladder wall thickening mimicking gallbladder cancer: a case report and literature review. BMC Gastroenterol, 2022, 22(1): 99.
38. Watanabe K, Kamisawa T, Chiba K, et al. Gallbladder wall thickening in patients with IgG4-related diseases, with special emphasis on IgG4-related cholecystitis. Scand J Gastroenterol, 2021, 56(12): 1456-1461.
39. Kuwatani M, Sakamoto N. Clinical and image characteristics of IgG4-related sclerosing cholecystitis. Diagnostics (Basel), 2021, 11(8): 1358.
40. Son JY, Kim YJ, Park HS, et al. Diffuse gallbladder wall thickening on computed tomography in patients with liver cirrhosis: correlation with clinical and laboratory variables. J Comput Assist Tomogr, 2011, 35(5): 535-538.
41. Bremer SCB, Knoop RF, Porsche M, et al. Pathological gallbladder wall thickening is associated with advanced chronic liver disease and independent of serum albumin. J Clin Ultrasound, 2022, 50(3): 367-374.
42. Liu Y, Wang K, Liu H. Gallbladder tuberculosis mimicking gallbladder carcinoma: A case report and literature review. Case Reports Hepatol, 2016, 2016: 3629708.
43. Xu XF, Yu RS, Qiu LL, et al. Gallbladder tuberculosis: CT findings with histopathologic correlation. Korean J Radiol, 2011, 12(2): 196-202.
44. Lee YH, Kim SH, Cho MY, et al. Actinomycosis of the gallbladder mimicking carcinoma: a case report with US and CT findings. Korean J Radiol, 2007, 8(2): 169-172.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Imaging diagnosis of non-tumor diseases of gallbladder

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content